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Articles By Jack Cush, MD

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Racial and Ethnic Determinants of Psoriatic Arthritis

A study from a large metropolitan registry of psoriatic arthritis (PsA) patients showed several racial and/or ethnic groups are underrepresented and demonstrate differences in disease activity.

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Leaving Academia (2.2.24)

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. This week we discuss hipsters undergoing hip replacement, pregnancy outcomes in RA and the future of academic clinicians.

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Pre-Treatment Testing with Biologics Falls Short

US commercial insurance claim analysis of laboratory screening and monitoring practices in chronic inflammatory skin disease (CISD) patients shows that < 60% received the recommended pretreatment testing when starting systemic immunomodulatory treatment.

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One-Third of Physicians Intend to Leave Academia

A cross-sectional survey of academic physicians shows that approximately one-third intend to leave their institutions in the next two years. Burnout, lack of professional fulfillment, and other personal and organizational factors were associated with intention to leave.

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Half of Subclinical Synovitis Patients May Remit

Ultrasound subclinical synovitis is found in a third of individuals at risk of rheumatoid arthritis (RA) patients; in half of these, subclinical synovitis resolves with a favorable outcome.

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Dead Words Eulogy

The trouble with rheumatology may be the words we live by. Welcome to the eulogy for rheumatology 'dead words'. We're here today to celebrate the loss of rheumatology past. These are dead words in rheumatology, words fortified unfortunately by history and habit. The lexicon of rheumatology is unique, it's challenging and it's mostly incomprehensible to those who don't know...but those are the cornerstones of the greatest of medical subspecialties. 

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Anti-Drug Antibodies and Biologic Drug Responses

A prospective cohort study suggests the presence of antidrug antibodies may be associated with bDMARDs nonresponse in rheumatoid arthritis (RA). Should we be monitoring ADAbs (especially in nonresponders)?

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Prevalence of Cardiovascular Disease in Rheumatoid Arthritis

A prospective study of the BioSTAR registry estimates the prevalence of cardiovascular disease in rheumatoid arthritis (RA) to be 4.6%.

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Best Treatments for COVID-Related MIS-C

The RECOVERY trial focused on pediatric MIS-C patients treated with immunomodulators and anti-cytokine therapy demonstrated the benefits of first-line therapy with intravenous methylprednisolone or second-line tocilizumab in children refractory to initial treatment.

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Severe Hypocalcemia Risk with Denosumab and CKD Patients

On 1-19-2024, the Food and Drug Administration (FDA) issued a Drug Safety Communication about the risk of severe hypocalcemia in chronic kidney disease (CKD) patients taking denosumab for osteoporosis, with an accentuated risk in older women who are dialysis-dependent. This report is an update to their November 2022 investigation, the results of a related study being recently reported in JAMA.

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