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William FC Rigby, MD, is Professor of Medicine of Microbiology and Immunology at the Geisel School of Medicine at Dartmouth-Hitchcock Medical Center in Lebanon, NH. He received his medical degree from Harvard Medical School in Boston, MA. He has spent nearly his entire career at Dartmouth. His research interests include the scientific underpinnings of the pathogenesis and treatment of rheumatoid arthritis.
The incredible potential of B cell depletion in rheumatic diseases was heralded by its activity in the treatment of rheumatoid arthritis (RA) over 20 years ago. Rituximab (RTX) was cemented into the armamentarium of RA by its efficacy in TNF-inhibitor inadequate responders (REFLEX).
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