Recent News
Reuters reports that a U.S. appeals court on Friday revived more than 500 lawsuits alleging that Merck failed to warn that patients taking alendronate for osteoporosis may be at increased the risk of atypical femoral fractures.Read Article
Economic and Mental Health Burden of Rheumatoid Arthritis
EurekaAlert!
A University of Mississippi-led comprehensive study of a disorder that affects 4.27 million Americans nationwide is revealing just how significant its burdens are on patients' financial well-being and quality of life. Patients with rheumatoid arthritis pay an average of $3,383 more per year on health care expenditures than those without the disorder, according to the study published in ACR Open Rheumatology, the American College of
Read Article
Is EBV relevant? It's certainly been linked to the etiol of SLE, RA, Sjögrens, & MS. Ronbinson et al suggests "EBV infection as a potentiator of autoimmune rheumatic diseases" and if Rx targeting of EBV may work in EBV-associated autoimmune diseases. https://t.co/RquS63c1st https://t.co/tPO59HW5wz
Dr. John Cush @RheumNow ( View Tweet)
NEJM Review Article on
"Cryoglobulinemia — One Name for Two Diseases "
(sign up for free read)
https://t.co/9FVhlBtDTE https://t.co/a23UygUUs9
Dr. John Cush @RheumNow ( View Tweet)
Cardiovascular health (CVH) is critical in arthritis care. NHANES study 5919 arthritis pts finds 10-point incr, in CVH score yielded significantly lower all-cause mortality risk (adj HR 0.72; 0.67–0.79); best results with OA/DJD, more than inflammatory arthritis.… https://t.co/etBbH7bH1D https://t.co/1is2VlT5sl
Dr. John Cush @RheumNow ( View Tweet)
EULAR has announced its new, open access journal - EULAR Rheumatology Open (ERO) https://t.co/7cueptyluo https://t.co/mRdfqPgmic
Links:
Dr. John Cush @RheumNow ( View Tweet)
ACR and Congress Address “Damaging” Cuts to Medicare MD Payments
The ACR commended the 233 bipartisan representatives who signed a letter urging House Speaker Mike Johnson (R-LA) and Minority Leader Hakeem Jeffries (D-NY) to support legislative action to address “damaging”… https://t.co/nVhRAeBf7y https://t.co/GwQTAi7GR1
Dr. John Cush @RheumNow ( View Tweet)
Inadequate Zoster Vaccination in Immunocompromised Patients
A VA study of shows that recombinant zoster vaccine (RZV) vaccination in immunocompromised patients or those receiving immunosuppressive medications is insufficient, given these are high risk individuals.… https://t.co/TahCte80wv https://t.co/KO0chO5rSD
Dr. John Cush @RheumNow ( View Tweet)
Men and Women Process Pain Differently
EurekAlert!
Men and women experience pain relief differently; a new study may help explain why women have more chronic pain and are less responsive to opioid treatments.
Read Article
Health Disparities in DMARD Use in RA
A UK study shows biological and targeted synthetic DMARD use in newly diagnosed rheumatoid arthritis varies markedly by ethnicity, age and setting - "one-size-fits-all approach" does not apply.
Read Article
Eu Heart J - Cardiometabolic risk factors in RA Pregancy rose in last 15 yrs. RA-Preg at higher risk of preeclampsia, peripartum cardiomyopathy, arrhythmias, acute kidney injury, venous thromboembolism during hospitalizations. https://t.co/7SnjWFluCf https://t.co/H93ELPZWWz
Dr. John Cush @RheumNow ( View Tweet)
GWAS study of 2.6 million people (120,295 w/ prevalent gout) detected 377 loci & 410 independent genes (149 prev unreported), includes genes of inflammation, epigenetic remodeling, cell osmolarity, NLRP3 activity, & clonal hematopoiesis (CHIP) https://t.co/GmXWtTlJkO https://t.co/xPK2Iy3NRj
Dr. John Cush @RheumNow ( View Tweet)
Run-Walk Exercise May Help Lower Back Pain
Adults younger than age 45 with chronic, nonspecific lower back pain saw significant pain relief with a structured run-walk program in a randomized trial.
https://t.co/8U8ovgQQkD https://t.co/zTENGgfJ3b
Dr. John Cush @RheumNow ( View Tweet)
Efficacy of Acupuncture for Sciatica
Real Chinese acupuncture was more effective than a sham version for treating sciatica stemming from herniated spinal disks in a randomized trial conducted in China.
https://t.co/ukfApikSOl https://t.co/6zu5YWPV0L
Dr. John Cush @RheumNow ( View Tweet)
ACR and Congress Address “Damaging” Cuts to Medicare MD Payments
ACR
The American College of Rheumatology (ACR) today commended the 233 bipartisan representatives who signed a letter urging House Speaker Mike Johnson (R-LA) and Minority Leader Hakeem Jeffries (D-NY) to support legislative action to address “damaging” payment cuts to physicians in the Calendar Year 2025 Medicare Physician Fee Schedule (MPFS) Proposed Rule.
Read Article
Inadequate Zoster Vaccination in Immunocompromised Patients
A VA study of shows that recombinant zoster vaccine (RZV) vaccination in immunocompromised patients or those receiving immunosuppressive medications is insufficient, given these are high risk individuals.
Read Article
Biologic (bio-originators) & biosimilar serious Infx rates are low & similar. Retro Study w/ 2+ yrs F/U shows hosp. Infx to be 7% infliximab & 2% etanercept. Similar SIE w/ ETA IR = 11.8 (7.9, 16.8) vs 8.4 (6.9, 10.1) & INFLX SIE IR= 33.4 (27.2, 40.1) vs 29.3 (26.6,… https://t.co/3VI47MjVb2 https://t.co/KHA1m5iefP
Dr. John Cush @RheumNow ( View Tweet)
Early bird registration for RheumNow Live is now open! Join us Feb 8-9 in Dallas, TX.
https://t.co/C2D8JDQNmz https://t.co/fiZamUcEyZ
Links:
Dr. John Cush @RheumNow ( View Tweet)
Metanalysis of 40 papers, 486,465 RA pts & 3,928 incident ILD outcomes shows no signif risk of ILD w/ DMARD use; no ILD risk w/ TOFA or TNFi (Oral Surveillance n=2,911; OR 0.94). MTX use yielded a Lower ILD risk (OR 0.49; 0.32 to 0.76) vs no MTX use. https://t.co/JGf0U3RS9w https://t.co/STDPSXN7zw
Links:
Dr. John Cush @RheumNow ( View Tweet)
Screening to Prevent Multimorbidity in Rheumatic Patients
A population based screening program of patients with chronic inflammatory rheumatic diseases (IRD) demonstrates that systematic screening IRD patients for multimorbidity increased preventive interventions and reduced… https://t.co/qh0mkN8HgD https://t.co/ggz5bafCMt
Dr. John Cush @RheumNow ( View Tweet)
ANA+ consult? 2 Yr study of 207 asymptomatic ANA-pos, found only 11% progressed to systemic autoimmune rheum Dz (89% did not). Progressors developed SLE (48%), Sjögren (22%), scleroderma (13%), RA (4%); Arthritis (RR 1.74) more likly in progressors https://t.co/53bmkQ0qj0 https://t.co/8VUxqxnuGl
Dr. John Cush @RheumNow ( View Tweet)
From the blog
Podcasts
Dot The I, Cross The T (10.11.2024)-
Stop Counting Bugs (10.4.2024)
RA Risk Radar: Heart Disease, Infection, and Malignancy Sponsored by AbbVie Medical Affairs-
Which One Is The Loneliest Number (9.27.2024)
Therapeutic Updates
RA Risk Radar: Heart Disease, Infection, and Malignancy
Sponsored by AbbVie Medical Affairs
Listen as rheumatologists Dr. Jeffery Curtis and Dr. Jon Giles review comorbidities that can occur as a consequence of uncontrolled, or under-controlled, inflammation in rheumatoid arthritis. In this conversation they share their clinical expertise on a range of topics, including risk assessment, risk management, and the importance of disease control.
Read Post
A review of two physician case reports. These cases are patients who presented with severe active manifestations of granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA).
Read Post
Poster Hall
