Lupus Linked With Greater Risk of Cardiovascular Complications of Childbirth

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Pregnant women with systemic lupus erythematosus (SLE) were more prone to cardiovascular complications during delivery, and their risk seems to have increased over the past 15 years, according to national administrative data.

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Rheum Manpower Needs - More Programs! (12.2.2022)

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Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.

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The spicy topic of turmeric in RA Curcumin has increasingly been promoted as a potential RA therapy, but data presented at #ACR22 suggests it is unable to do any better than placebo in replacing conventional rheumatoid arthritis therapies. https://t.co/C0O0DyXn34 https://t.co/kv3dw476dT

Dual target blockade may be better than one in SLE Inhibition of B-cell Activating Factor (BAFF) has revolutionised the treatment of patients with systemic lupus erythematosus (SLE).https://t.co/uu6ygb4l8B https://t.co/nLO3oSiEVa

JAK inhibitors in rheumatic diseases Dr. Antoni Chan ( @synovialjoints) discusses abstracts 0510 and 0404 at #ACR22 https://t.co/7SSJITLrRT https://t.co/utjf8vlJof

AI Future of Sacroiliitis Assessment Dr. Rachel Tate ( @uptoTate) speaks with Dr. Fabian Proft about Abstract 0383 at #ACR22 Convergence. https://t.co/pfeW4iQBLq https://t.co/0lFx6CpWCx

Can I stop Methotrexate in RA? Dr. Pope and Dr. Meng discuss Abstract 0916 at #ACR22. https://t.co/0hK5kNHlrS https://t.co/AXJija7Yzo

Remibrutinib in Sjogren's Syndrome Dr. Putman reports on abstract 1113 presented at #ACR22 Convergence Abstract 1113: Remibrutinib (LOU064) in Sjögren’s Syndrome: Safety and Efficacy Results from a 24‑Week Placebo-controlled Proof-of-Concept Study https://t.co/ymFkNWPaXo https://t.co/0k6vLIu0Ku

Rheum Drugs & IDSA Guidelines to Treat COVID-19 https://t.co/39wTAKW83E https://t.co/ir1x66FSQ8

RECITAL Trial: RTX vs. CTX in CTD-ILD A UK study suggests the equivalent outcomes when patients with ILD associated with CTD are treated with either intravenous RTX or CTX, but with fewer adverse events with RTX. https://t.co/5yaPDaw8pZ https://t.co/kcKLkIv1bK

Recent CDC/MMWR report shows Paxlovid x 5days (including those w/ prior COVID or vaccination), had a 51% lower hospitalization rate within 30 days after diagnosis than those not prescribed Paxlovid. Use it irrespective of vaccination status https://t.co/CBc1VBSDFR https://t.co/EC8QGaFrb3

Future therapy? Nanoparticles laced with rapamycin to nanoparticle stimulate regulatory T cells to suppress autoimmune disease (tested in a mouse model). https://t.co/JHFh82siff https://t.co/Y8itPXiPho

Impressive free read and review of Neutrophils and Netosis in Autoimmune and Autoinflammatory disorders (Nature Reviews) from Kapland & Wigerblad at the NIH. https://t.co/w4cIwcQMkt https://t.co/ReA9xM2X4j

Rheum Drugs & IDSA Guidelines to Treat COVID-19

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The Infectious Diseases Society of America has recently updated its recommendations with regards to the treatment of severely ill, hospitalized COVID-19 infected patients and also about the appropriate use of anti-IL-6, JAKs and colchicine.

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Topic Podcasts - Lupus Part2 #ACR22 Daily Recap: Saturday Recap New Treatments for SLE? https://t.co/uRI3Q3eI6E https://t.co/wBXfXw7z8J

Just Can’t Get Enough of Hydroxychloroquine Several studies on HCQ dosing were presented in the poster and abstract sessions. HCQ has numerous benefits backed by evidence and unless absolutely contraindicated, patients should be maintained on it. Yet...https://t.co/n8drUDDDjh https://t.co/AIoV3s2VhJ

Steroid injections worsen knee arthritis Two studies comparing injections commonly used to relieve the pain of knee osteoarthritis found that corticosteroid injections were associated with the progression of the disease. https://t.co/v7cDBKfM9c https://t.co/sbJ1ro0orW

Low Dose IL-2 Therapy in Sjögren’s There is a large, unmet need in treating Sjögren’s syndrome, yet a new randomized clinical trial has shown that lLD-IL-2 was effective and well tolerated in patients with pSS, with evidence of restored immune balance. https://t.co/0obaV0wnGX https://t.co/vgy91cYYvp

Topic Podcasts - Lupus Part1 -A Novel Treatment Response Measurement Tool for Lupus -Breakthrough COVID infection in SLE during Omicron era Effect of voclosporin in class V lupus nephritis and more.https://t.co/RVhpZtoo6b https://t.co/jjOZbLZN9m

Pre-RA Pharmacological Interventions: Delaying is not Enough Dr. Aurelie Najm reports on both the Great Debate as well as abstracts 0530, 1603 at #ACR22 https://t.co/n8hzJMpmWO https://t.co/8OISSK34No