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RheumNow Live Preview (1.30.2026)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from RheumNow.com 

Top 5 reasons to attend RheumNow Live 2026 

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Aorta

Aortitis in Giant Cell Arteritis Treated with Tocilizumab

d Jack Cush, MD

The The Toci

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errors.doctor

Retractions in Rheumatology

d Jack Cush, MD

Retraction of rheumatology studies is not uncommon; a recent analysis shows retractions have risen substantially.

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Notch and TGFβ Signaling in Refractory Rheumatoid Arthritis

d EurekAlert!

Spatial transcriptomic profiling of rheumatoid arthritis (RA) synovial biopsies (pre- and post-treatment) has revealed new insights into the pathobiology or treatment resistent RA. 

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D2T RA Cover

Difficult to Treat Rheumatoid Arthritis

d Jack Cush, MD

Dr. Cush addresses the management of difficult-to-treat rheumatoid arthritis (D2TRA).

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TOPKAT Trial: Partial vs Total Knee Replacement

d MedPage Today

Patients with osteoarthritis (OA) primarily affecting only one knee joint compartment did just as well with partial knee replacement (PKR) as with total arthroplasty after 10 years in a randomized trial -- and maybe a little bit better.

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DMARD Responses in Localized Scleroderma

d Jack Cush, MD

JAMA Dermatology has published the results of a juvenile localized scleroderma (JLS) trial showing that mycophenolate mofetil (MMF) and methotrexate (MTX) are equally effective in treating JLS, noting low flare rates and possibly better tolerability with MMF.

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Remission? Single center study of 100 RA, 100 SLE pts assessed by SLEDAI-2K, SDAI, VAS. Remission/LDA found in 88% of 392 SLE visits & 91% of 389 RA visits(p=NS). Remission was more common in SLE vs RA (79% vs 69%; p= 0.0018). https://t.co/ZPRrYQMsCT

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UK NHS has cut use of physician associates over ‘substitute doctor’ fear. The reduction in roles is being blamed by union leaders for an increasing in waiting times and consultants’ workload. Plus 76% of PAs said their scope of practice had been restricted in recent months. GMC https://t.co/i0l4x9UVhZ
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Physical activity (PA) is assoc w/ reduced all-cause mortality in RA pts. Study of 1493 NHANES & 1724 UK Biobank RA cohorts showing robust inverse association between PA and all-cause mortality (HR: active = 0.48, highly active = 0.61) https://t.co/K6ALzqP3QQ https://t.co/2XJ0zD7FA3

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PA Assn President position on DES/gov Proposed Rule on Federal Student Loans "... loan rule is deeply flawed, outside the Dept’s authority...inconsistent w/.. Trumps rural healthcare workforce priorities.. excluding PAs will decimate US healthcare workforce pipeline" https://t.co/p5owv3Ui2B
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Electronic EHR reminders to deprescribe works! EHR study of 1146 pts(mean 74 yrs) showed 2 methods of E-reminder notifications resulted in either a 10.4% or 6.5% deprescribing (vs usual care); deprescribing was 40% more likely (RR 1.40; 95% CI, 1.14-1.73) https://t.co/sXnW5gUP0q https://t.co/n9LhUG612M

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APP Survey Results: 2017 and 2025 https://t.co/UEfYsKL74u https://t.co/SYTA7OOOvV

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Full read review of the Mechanistic Effects of Methotrexate in the Treatment of Rheumatoid Arthritis. https://t.co/PrMyZ7q3wX download here: https://t.co/fvEocwsXIv https://t.co/ZWVctochHV

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B Cells at the Brink in Sjögren Disease The current issue of Arthritis & Rheumatology reviews the current understanding of the immunopathogenesis of Sjögren disease (SjD) and how this understanding has informed drug development for this systemic autoimmune disorder. https://t.co/zI7lQ5N54o
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Consensus on Managing Vertebral Fractures in Advanced CKD A coalition of leading international experts has released the first comprehensive Consensus Statement on the Management of Vertebral Fractures in Chronic Kidney Disease (CKD) Stages G4–G5D. The statement highlights a https://t.co/gilX13EaUi
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Japanese nationwide survey of 1943 RMD pts taking Azathioprine (AZA) 34% had adverse events: hepatobiliary (149%), GI (10%), blood/lymphatic (9%), infections (5%), & skin (2.4%). AEs lead to 71% D/C AZA. Serious AEs (Gr ≥3) higher w/ older (OR 2.5), & SLE (OR 2.3) https://t.co/lVNYVQATfx
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Minnesota Mayo clinic retrospective, population study of RF & CCP in 1373 incident RA pts. At Dx, 37% dual seropositive, 13% +CCP only, 12% +RF only, & 38% seronegative. zDual seropositives had more erosions (31%) & flares (69% vs 51%). But +RF only highest mortality (adj 2.18) https://t.co/hPQewVgPoq
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IXCHIQ - a live-attenuated chikungunya virus vaccine: 10-30% have mild-moderate adverse effects, w/ headache, fatigue, & myalgia. <3% have severe AEs. Rare reports of encephalitis in elderly post Ixchiq, due to type I IFN-neutralizing autoantibodies (same w/ yellow-fever Vax) https://t.co/3VlZCd4sGc
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2026 SPARTAN Annual Meeting (May 14-16; Toronto) is now accepting abstract submissions! A premier mtg brings together cutting-edge researchers and teachers in spondyloarthritis (SpA). Submit your abstracts by Feb 1st!! https://t.co/IBXEkSxpDy https://t.co/cS7exDUc9H

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