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RheumNow Podcast – Better Ways to Treat Gout (11.8.19)
Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.
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One thing that really impressed me from RITAZAREM (ritux vs azathioprine maintenance following ritux induction in AAV) apart from fewer relapses with ritux, is how well it was tolerated. Not even a hypogammaglob signal! #ACR19 ABST0806 @RheumNow https://t.co/9l1jqlX0jg
David Liew drdavidliew ( View Tweet)
RITAZAREM Trial
Fixed interval 4 monthly repeat dose Rituximab vs Aza for maintenance
Pop: AAV at relapse, given 375mg/m2
Rituximab seemed superior
#ACR19 @rheumnow
More details Abst0806
Dr Irwin Lim _connectedcare ( View Tweet)
EMA has approved the subcutaneous version of CT-P13 an infliximab biosimilar based on this trial by Rene Westhovens. Equal efficacy of IV and SC CT-P13 with great maintenance on SC form. Interestingly high trough levels with SC CT-P13. #ACR19 @RheumNow Abst 807 https://t.co/hfrtJRMPdt
Dr. John Cush RheumNow ( View Tweet)
In you #SLE pts how do you routinely assess CV risk
Dr. John Cush RheumNow ( View Tweet)
Great data on reducing low benefit care in rheum pathology ordering. Reducing dsDNA requests in patients with a negative ANA #ACR19 @RheumNow Abstract 0265 https://t.co/b5gWwPi487
Philip Robinson philipcrobinson ( View Tweet)
RheumNow’s expanded coverage of the #ACR2019 annual meeting is sponsored in part by Sanofi Genzyme and Regeneron. All content chosen by RheumNow and its faculty.
Dr. John Cush RheumNow ( View Tweet)
Abstract 0348 #gout Details of the changes over time in gout medications in US RISE database.
Allopurinol and pegloticase slowly grinding higher… Lesinurad increased significantly in comparison
@RheumNow #ACR19 https://t.co/VcqNtB2eXN
Philip Robinson philipcrobinson ( View Tweet)
CVS risk in black patients with SLE (retro cohort)
18x higher in early SLE & over long-term, 6x
Highest risk at 1 and 10yrs after SLE diagnosis
Discoid rash 3x assoc with CVD
#ACR19 @rheumnow Abst0805
Dr Irwin Lim _connectedcare ( View Tweet)
Holy smokes! 18x higher risk of cardiovascular disease in Black SLE patients, highest at 1 and 10 years after diagnosis - Dr Shivani Garg #ACR19 @rheumnow #Abstr #ACRBest https://t.co/kXoMNu4QKb
Jonathan Hausmann MD hausmannMD ( View Tweet)
Pneumococcal vaccine recommendations for pts with AID are confusing and data is C level - but we still recommend prime/boost administration of PCV13 followed by PPSV23 @RheumNow @LCalabreseDO @BetsyKirch #ACR19 #cleclinicrheum https://t.co/WFBjQRRgmb
Cassandra Calabrese CCalabreseDO ( View Tweet)
Plenary session shows AA/blacks at higher risk for #SLE & that blacks have 16 fold increased risk for IHD, CVD. CV risk accelerated at yrs 1 & 10. Copy & paste. #ACR19 @RheumNow Abst 805 #ACRBest https://t.co/kgfwjd1XOc
Dr. John Cush RheumNow ( View Tweet)
RheumNow’s expanded coverage of the #ACR2019 annual meeting is sponsored in part by Horizon Therapeutics. All content chosen by RheumNow and its faculty.
Dr. John Cush RheumNow ( View Tweet)
What percentage of your SLE and RA patients receive HCQ above the 5mg/kg recommended by AAO? #ACR19 @rheumnow #Abstr #ACRBest
Jonathan Hausmann MD hausmannMD ( View Tweet)
How do you taper steroids in RA?
I take a personalised approach i.e. I guess based on experience of similar pt situations & what I think the pt will tolerate.
Is it evidence-based? Not really.
Is there any evidence to guide it? Well...😐
@umichmedicine #ACR19 ABST0554 @RheumNow https://t.co/YFlvyYuBee
David Liew drdavidliew ( View Tweet)
MTX and RTX significantly reduce immunogenicity it flu and pneumonia vaccines. When possible, time appropriately! @RheumNow @LCalabreseDO #ACR19 https://t.co/udmqkbLG64
Cassandra Calabrese CCalabreseDO ( View Tweet)
@RheumNow #ACR19 https://t.co/fmLAr2X4y5
Olga Petryna DrPetryna ( View Tweet)
Black vs White US data
2-3x incidence in black patients
Deaths 13yrs sooner with 2-3x higher mortality
#ACR19 @rheumnow Abst0805
Dr Irwin Lim _connectedcare ( View Tweet)
By the way, how many of you use low dose aspirin routinely in SLE pregnancies?
#ACR19 @rheumnow
Dr Irwin Lim _connectedcare ( View Tweet)
What imaging do you use in gout? Check out the updated PANLAR recommendations abst#301 @RheumNow #ACR19
Dr. Rachel Tate uptoTate ( View Tweet)