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EULAR 2023 – Day 2 Report
Day 2 at the international EULAR Congress meeting is always bigger and busier. There were sessions on JIA therapies, crystal arthritis, novel drugs for SLE and Sjogren's, early RA and preclinical RA interventions, IgG4 disease, osteoporosis and the growth and application of artificial intelligence in medicine and rheumatology.
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Better at Predicting RA from MRI: Humans or Computers?
An artificial intelligence model to assess pre-RA hand MRIs has confirmed what human readers have known before: that bone marrow edema and tenosynovitis are objectively the best predictors of future RA development in patients with clinically suspect arthralgias or undiffer
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AOSD: Young vs. Elderly Onset
Adult onset still's disease (AOSD) is an autoinflammatory condition characterized by fevers, arthritis, and rash. It is considered an orphan disease because of its low prevalence - it is reported anywhere between 16 to 40 per ten million.
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#EULAR2023 #OP0289 We need to improve health equity in the care of people with arthritis. An online survey showed that Black, Indigenous and People of Colour (BIPOC) Women in Canada faced a)unique & disproportionate barriers and b) complex experiences of discrimination @RheumNow https://t.co/hnahUIb9Xb
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Reflections on COVID-19 and autoimmunity: post-vaccination autoimmunity is not specific to COVID-19, autoimmunity is not autoimmune disease, the large numbers may result in the perception of increased occurrence of autoimmunity, Schulze-Koops H, COVID-19, #EULAR2023 @RheumNow https://t.co/Rm9OEWrBzo
Dr. Antoni Chan synovialjoints ( View Tweet)
The modern day poster tour #EULAR2023: the posters & speakers come to you, broadcast through a headset (it’s almost like a silent disco, in a hall with lots of background noise).
Definite innovation but at capacity, wish more people could tune in on their own devices @RheumNow https://t.co/sOXnYctsfN
David Liew drdavidliew ( View Tweet)
A shame. Pts with #scleroderma are dying waiting for organ transplant- we should list and work them up for Tx earlier. PAH Pts May do worse @eular_org #EULAR2023 @RheumNow OP0241 https://t.co/8ZlHJmETGA
Janet Pope Janetbirdope ( View Tweet)
Let le introduce you to ARTHUR 🤖
A very skilled robot who scans your hands and wrists in 15 mn 🤚
Amazing to see new #AI developments that will make our lifes’ easier!
#EULAR23 @ROPCA3 @JustSoren Stand M6
@RheumNow https://t.co/7PtR2CGqTt
Aurelie Najm AurelieRheumo ( View Tweet)
Should we use #immunesuppression EARLY in #scleroderma to prevent #ILD? Answer from a study comparing Y vs N immune suppression- there was no difference in FVC decline. Maybe not a long enough study, ? Chanelling bias scleroderma #lung #disease OP0239 @RheumNow #EULAR2023
Janet Pope Janetbirdope ( View Tweet)
#ClinicalPearl Rx of #scleroderma #ILD -add another drug. MMF, then Cyclo, Rituximab, ?tocilizumab; if progressive fibrosis then #Nintedanib ?Pirfenidone Small RCT of MMF v Tacrolimus - looked the same -helpful if MMF fails, future pregnancy OP0240 @RheumNow #EULAR2023 @eular_org https://t.co/XWphyEO2JJ
Janet Pope Janetbirdope ( View Tweet)
An AI algorithm to predict opined related deaths
UK database >1000000 pts, 1200+ opioids related deaths
Risk factors:
Substance used disorder
Hx self harm
Alcohol abuse
Oxycodone
Liver disease
Concomitant gabapentinoids & BZD
*no pictures allowed*
@Rheumnow OP0269 #EULAR23 https://t.co/II96fnhqy3
Aurelie Najm AurelieRheumo ( View Tweet)
Risks for #ILD #SSc lung progression. FVC decline >5% is the gold standard but there are other criteria. OP0236 #EULAR2023 @RheumNow @eular_org #scleroderma Some criteria are stricter - larger PFT changes and/or worsening symptoms or fibrosis, so depends on def’n for % def’n https://t.co/TCuX2KY64w
Janet Pope Janetbirdope ( View Tweet)
Very much looking forward to our joint PRP-HRP-Rheum session later today
How to improve & implement apps for self management in clinical care @ElenaNikiUK @fibrofella @ProfYelizPrior
We will discuss and reveal the results of a survey made for #EULAR23
@RheumNow @eular_org https://t.co/R5vTW3FeWO
Aurelie Najm AurelieRheumo ( View Tweet)
RheumNow Eular 2023 Daily Recap Series https://t.co/oZXuyv8wL5
Dr. John Cush RheumNow ( View Tweet)
Always great to have @EMA_News to come and to talk to us at #EULAR2023
Our meds are very important to us, and the more we can understand how decisions are made and RWE is collected, the better 👍
@RheumNow https://t.co/hSutraUsFD
David Liew drdavidliew ( View Tweet)
• Erdheim-Chester disease (ECD) is associated with Langerhans cell histiocytosis (LCH)
• Bone pain, xanthelasma, hairy kidney
• Differential diagnoses of LCH
• BRAF mutation associated with cardiac and neurological phenotype of ECD
Haroche J, Papo M
#EULAR2023
@RheumNow https://t.co/AzKJKp82nq
Dr. Antoni Chan synovialjoints ( View Tweet)
Do we use too much PNL in GCA (when not using TCZ)? Could we wean quicker?
Salvarini group n=22
26w PNL weaning protocol from GiACTA, but no TCZ
10/26 in relapse free remission at 1y
Much less PNL, still some steroid AEs
Way of the future for some?
POS0728 #EULAR2023 @RheumNow https://t.co/qeZHeCi9vq
David Liew drdavidliew ( View Tweet)
You need to see this! Albert with a Left V1 distribution of #shingles is a ‘bot’ who interacts with #rheumatologists at #EULAR2023 @RheumNow @eular_org #artificial #intelligence https://t.co/gDwzc3NX7v
Janet Pope Janetbirdope ( View Tweet)
#EULAR2023 #POS0627 Researchers in Manchester identified several proteins associated with subclinical cardiovascular abnormalities on Cardiac MRI in Scleroderma using proteomics. Need validation. Could be useful for stratification and identify therapeutic targets @RheumNow https://t.co/55eNGhMu5f
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
#EULAR2023 #POS0618 This is cool! Researchers from Switzerland are developing new Quantitative Radiomic Risk Score (from HRCT) to stratify response to Anti-Fibrotic in #ILD. Data presented in pre-clinical study & paralleled molecular effects. Human study is in progress @RheumNow https://t.co/qAsWew4FEO
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
