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ACR 2022 - Day 1 Report

Jack Cush, MD

The masses have returned to ACR22, a live, face-to-face, and virtual, meeting that began Saturday in Philadelphia. There were hassles and glitches, yet the education and sessions were as you’d expect with many good presentations worth recapping.

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Puzzle pieces

Where are we with treating Pre-Rheumatoid Arthritis?

Richard Conway, MBBChBAO, PhD

The ability to prevent RA in individuals at risk is a holy grail in rheumatology. There is a long history dating back to the PROMPT trial of methotrexate and PRAIRIE trial of rituximab. Both otrials showed an effect, but it seemed more likely to be a delaying of RA than prevention or modulation. Framing it another way, there were better outcomes in pre-RA because we were actually treating RA as it emerged with a proven effective treatment. It is in this setting that three trials of ongoing studies in RA preventative therapy are presented at ACR.

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EULAR19.abstract.jpg (keep)

ACR Best Abstracts - Day 1

Jack Cush, MD

The RheumNow faculty reporters have been scouring the meeting and online presentations to find the best abstracts from ACR22. Here are some of their choice abstracts reported today on day 1 of ACR 2022 (#ACRbest).



 

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Are we really treating Psoriatic disease if we only address active disease domains and T2T?

Rachel Tate, DO

It’s widely accepted that Psoriatic disease has multi-system, multi-domain potential that can lead to life altering complications if left untreated or undertreated. Rheumatologists have shifted the way we discuss treatment options and disease state expectations with patients. Two #ACR22 abstracts stood out to me regarding the Psoriatic disease patient experience and will, ultimately, add to what I do in clinic. 

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pregnant, pregnancy, mother, fertility

Updates on Reproductive Health in Women with SLE

Catherine Sims, MD

Is patient-administered cervical cancer screening an option for women with SLE? Should I prescribe estrogen containing contraceptives to SLE women with APL antibodies? What complications should I be aware of in pregnant women with SLE? Here are three abstracts that provide insight.





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bacteria,infection,color

Infections in pre-RA: a cause or a consequence?

Aurelie Najm, MD, PhD

Rheumatoid arthritis is known to be associated with a higher risk of infections. In abstract 0535, Porter and colleagues have assessed infection rates in the pre-RA and early RA phases as defined by antibiotics prescription and hospital admissions with an infection main diagnostic code in the UK National database.

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Stop repeating the #ANA test! 46% of all ANA tests were repeat tests in this study. #HealthCareCost #NoUtility #ChooseWisely abst#1278 @rheumnow #ACR22 https://t.co/K7oyqJYvi9

Links:

TheDaoIndex KDAO2011 ( View Tweet)

#ACR22 Advancing Telemedicine in Rheumatology '60% prefer telemedicine for routine visits and review lab results' https://t.co/HUgoocXodE @RheumNow #ACR22

Links:

Akhil Sood MD AkhilSoodMD ( View Tweet)

#abs0948 #acr22 @rheumnow perception on fertility&ART in pts w/rheum Dx: 60% believe their Dx affects fertility/25% believe meds do: most cited MTX, steroids, TNFi, HCQ, NSAIDs. 92% heard of ART but unsure if safe or successful w/their Dx. Hx of infertility 29%/only 52% go w/ART https://t.co/lmaM773gP5
Olga Petryna DrPetryna ( View Tweet)
Abs 0698 at #ACR22 finds that a 20 pack-year or more of cigarette smoking assoc'd w/ a modestly higher risk of incident PMR among women. Yet another reason to encourage smoking cessation in patients. @RheumNow https://t.co/HOVTIPSjOi https://t.co/Akuukxb90Q

Links:

Dr. Rachel Tate uptoTate ( View Tweet)
Did you know that the first virus, the tobacco mosaic virus, was described in 1892? @AdamJBrownMD gave a fascinating lecture today regarding that included the history of viruses. #ACR22 @RheumNow

Dr. Rachel Tate uptoTate ( View Tweet)

Do you know the 3 types of Y. Pestis plague? @AdamJBrownMD reviews the Bubonic, Pneumonic, and Septicemia plagues at #ACR22 @RheumNow. Most recently, there was an outbreak of Pneumonic plague in Madagascar in the 2010s!

Dr. Rachel Tate uptoTate ( View Tweet)

MEFV mutation protected against the plague. Protected against deactivation of inflammasome by yersinia pestis. @RheumNow #ACR22 #rheuminations https://t.co/OqBay6Svdb
Julian Segan JulianSegan ( View Tweet)
Ab0574 #ACR22: Osteoporosis in Men - Under-recognized? Under-Screened? Under-Diagnosed! @AMollaeianMD: Retrosp study >65 yo <1% M have DEXA compared to 7-10% in F in 2010, 2018, and 2021 Hip fx 4.1% F, 3% M DEXA declined in M between 2010-2018, no change in 2021 🦴🦴🩻 @RheumNow https://t.co/LbmxLnIX1Q
Eric Dein ericdeinmd ( View Tweet)
In-person meetings are tough. Virtual meetings are tough. But hybrid meetings are logistical nightmares Would've liked better WiFi and a live poster hall, but a HUGE credit to @ACRheum on planning a great #ACR22 hybrid meeting. Really amazing job @RheumNow

Eric Dein ericdeinmd ( View Tweet)

GPA pts can have dacryoadenitis (ddx 👇) where pt's lateral eye/s can be curved due to swelling. How to examine? Use thumb to retract eyelid & reveal lacrimal gland underneath, ask pt to look medially #ACR22 @RheumNow @rheumarhyme @doktora_ging @PhRheumaJr #RheumTwitter https://t.co/pJYMffhYWx
sheila RHEUMarampa ( View Tweet)
ACR Best Abstracts - Day 1 The RheumNow faculty reporters have been scouring the meeting and online presentations to find the best abstracts from ACR22. Here are some of their choice abstracts reported today on day 1 of ACR 2022 (#ACRbest). https://t.co/ndSBqYszlo https://t.co/vOHtLTFux6

Links:

Dr. John Cush RheumNow ( View Tweet)
How can we differentiate statin-assoc autoimmune necrotizing myopathy from toxic statin #myopathy?🔎 Remember this important slide👇 #ACR22 @Rheumnow #acrreview https://t.co/hKMJuGDJWt
sheila RHEUMarampa ( View Tweet)
Abstr #0195 examined acceptance of Virtual Reality among pts w/ rheumatic diseases (RD) - VR naïve & experienced were willing to use VR to manage their RD - VR experienced pts had ↑ % of perceived usefulness & anticipated enjoyment of VR in dx and mgmt of RD @RheumNow #ACR22 https://t.co/r7X8Kqp8UN
Akhil Sood MD AkhilSoodMD ( View Tweet)
This year, as every year, at ACR (and EULAR) I am amazed by some of what are oral presentations vs what is in the posters. Please check out the poster sessions, there are some absolute gems in there! I will amplify the ones I find that I feel competent to discuss #ACR22

Richard Conway RichardPAConway ( View Tweet)

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