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A prospective analysis of newly diagnosed, inflammatory arthritis (IA) patients suggests that perceived distress (stress) increases the odds of incident IA.
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A study of 527 patients receiving daily hydroxychloroquine (HCQ) concluded that hydroxychloroquine blood levels may predict future HCQ retinopathy.
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Highlights from Tuesday and Wednesday (days 3 and 4) from the ACR annual meeting include: the important and impactful abstracts covered by the Rheumatology Roundup session; upadacitinib clinical trials; and the baricitinib CV and VTE safety analysis.
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Arthritis Care & Research reports that juvenile arthritis (JA) patients may have a higher risk if coronary artery disease (CAD) in adulthood.
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Dr. Jack Cush delivers select commentary on select news and journal articles from the past week on RheumNow.com.
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The National Rheumatoid Arthritis Society's (NRAS) annual audit has identified significant treatment delays for patients with suspected early inflammatory arthritis could result in unnecessary harm.
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Intra-articular sprifermin given to patients with symptomatic and radiographic knee osteoarthritis has been shown to significantly improve total femorotibial joint cartilage thickness after 2 years, but without significant clinical benefits. Which begs the question, why is there a disconnect between radiographic disease modification (cartilage thickness) and symptomatic improvement?
Dr. John Cush
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RheumNow Survey for Rheumatologists – In Giant Cell Arteritis - When do you add a steroid sparing agent? https://t.co/qhpOxYhsYV
Dr. John Cush
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RISE registry: among 7,274 RA pts w/ serial data [RAPID3 (78.9%) & CDAI (34.2%)]. Amongst those w/ moderate/high disease activity, frequency of DMARD change was low (36%-55%). Less likely to change was elderly, Combo DMARDs or biologics. https://t.co/IppHCxJWk1
Dr. John Cush
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Followup of 783 tofacitinib‐treated psoriatic arthritis patients finds increases in LDL and HDL 9% to 14% after 3 and 6 months of therapy with a low risk of HTN or MACE events https://t.co/fh6UbmF3lr
Dr. John Cush
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RheumNow LIVE VOTE Survey: When treating a patient for GCA, when might you add a steroid-sparing agent?? If youre a RHEUMATOLOGIST - please vote in our quick 4Q survey https://t.co/qhpOxYhsYV
Dr. John Cush
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Comparison of 69 SLE pts w/ C/S+ infection vs 69 SLE without infx shows that serum procalitonin did not distinguish those w/ infection, BUT C-reactive protein did successfully identify those SLE patients with infection https://t.co/HMHqfaP0Cg
Dr. John Cush
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Taiwanese Claims data study shows the risk of opportunistic infection in ~77K autoimmune pts shows OI highes in PM/DM cases (61.3/1000PY), followed by SLE (43.1/1000PY), SSc (31.6), RA (25), and pSS (24.1). OI risk highest during 1st year https://t.co/YKP7ZF7FIx
Dr. John Cush
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Study of 179 RA pts achieving remission on TCZ- SC 162 mg qwk randomized to continue qWk or space out to q2Wk -- Weekly Actemra better maintained remission (90% versus 73%; P = 0.004), but then again 73% did well w/ spacing to every other week. https://t.co/ywvsDMxS6M
Dr. John Cush
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Logical + Data-driven = Annoying. (If you have high standards does that make you arrogant?)
Dr. John Cush
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RheumNow Podcast is up! When you're hot you're hot! Watch it on youtube>> https://t.co/GlqMzjUnhE or listen to the podcast on iTues, Apple podcast or on Stitcher or SoundCloud>> https://t.co/a1zE7VXtog
Dr. John Cush
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China retrospective study of 727 SoA abd 857 RA pts shows risk of H. Zoster same between SpA & RA (aHZ=0.97), but was significantly higher with MTX (adj HR 3.47) and infliximab (adj HR 10.67) https://t.co/gpictKPpIT
Dr. John Cush
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RheumNow Podcast is up! When youre hot youre hot! Watch it on youtube>> https://t.co/GlqMzjUnhE or listen to the podcast in your car on iTues, Apple podcast or on Stitcher or SoundCloud>> https://t.co/a1zE7VXtog
Dr. John Cush
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How would you describe your "BEST" patient in just 3 words? https://t.co/j1CEAiUdvo
Bharat Kumar
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How I feel when I switch a patient from a biologic to a biosimilar. #Rheum https://t.co/6pbdJ3u3U6
