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Why should we care about preclinical RA? Goal: to treat once and stop the trajectory of the disease. – Dr. Gabalawy #RNL2024 @rheumnow https://t.co/afbpvrZV8v

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TheDaoIndex KDAO2011 ( View Tweet)
<20% of anti-CCP+ pts without arthralgia with develop RA in 5 years! Dr. H. Gabalawy #RNL2024 @RheumNow https://t.co/OXe7EWfCmc

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Dr. Rachel Tate uptoTate ( View Tweet)
#RNL2024 @RheumNow TREAT-EARLIER - MTX for Clinically Suspect Arthralgias No overall diff vs PBO High risk pts had benefit, but not sustained at 2 yrs But sustained reduction in HAQ & MRI inflammation - Signs for hope? Overall, prevention studies have been disappointing https://t.co/DtBlGaw0Lf

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Eric Dein ericdeinmd ( View Tweet)
Rheums are "all over the map" but tend to skew conservatively when treating pre-clinical RA. Dr. H Gabalawy discusses the results of a case-driven polling question at #RNL2024 @RheumNow. Be sure to register at https://t.co/DXQ0KCelIh to hear his, and other, lectures to weigh… https://t.co/Yo3ChNwNIO https://t.co/wD3AMUDNr9

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Dr. Rachel Tate uptoTate ( View Tweet)
“At 2 years, 50% of patient with +RF/+CCP Ab will develop RA, at 5 years, 70%” – Dr. Gabalawy on can we predict who will get RA, is there a point of no return, can we prevent the progression #RNL2024 @rheumnow https://t.co/G8Rxd3CAoi

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TheDaoIndex KDAO2011 ( View Tweet)
Seropositive RA is a spectrum to disease Hani El Gabalawy @RheumNow #RNL2024 Genetic and environmental factors affecting autoimmunity and leading to disease Clinical suspect arthralgias usually finds "imminent RA", may be too late at that stage for prevention https://t.co/mGclCr3cth

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Eric Dein ericdeinmd ( View Tweet)
Dr. Hani Gabalawy shared his pre-clinical stages of seropositive RA --Break in the immune tolerance > pathogenic autoimmunity > RA Unknowns: timeline, can we arrest pre-clinical stages, etc? #RNL2024 @RheumNow https://t.co/8cMNGKM4rk

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Dr. Rachel Tate uptoTate ( View Tweet)
Using diet to shape the microbiome and to improve outcomes in inflammatory arthritis and response to medication. An anti-inflammatory and Mediterranean diet can help improve outcomes in RA, Monica Guma #RNL2024 @RheumNow https://t.co/x64Tbseuvz

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Dr. Antoni Chan synovialjoints ( View Tweet)
"The gut microbiome may affect how patients respond to their therapies" - Dr. Guma another reason why diet is important #RNL2024 @rheumnow https://t.co/7qI72HWRg0

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TheDaoIndex KDAO2011 ( View Tweet)
“Even a cookie changes the gut microbiota!” – Dr. Guma showing dynamic microbiota changes to the food we eat and even to the medications we take. #RNL2024 @rheumnow https://t.co/5d6Ld39BzG

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TheDaoIndex KDAO2011 ( View Tweet)
Monica Guma at #RNL2024 @RheumNow How does Mediterranean diet help inflammation? Maintains healthy microbiota Enhancing production of anti-inflammatory metabolites Maintains intestinal barrier integrity https://t.co/CyzTGBJzhm

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Eric Dein ericdeinmd ( View Tweet)
You are what you eat! So how does the Mediterranean diet affect the gut? *maintaining/shaping healthy gut microbiota *enhancing anti-inflammatory metabolite production *maintaining intestinal barrier integrity Dr. M. Guma #RNL2024 @RheumNow https://t.co/O9by7CahRW

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Dr. Rachel Tate uptoTate ( View Tweet)
How does the Mediterranean diet affect inflammation? Dr. Guma noted the diet helps to: 1. maintain healthy microbiota 2. enhance production of anti-inflammatory metabolites 3. maintain intestinal barrier integrity. #RNL2024 @rheumnow https://t.co/d3ByStvXyR

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TheDaoIndex KDAO2011 ( View Tweet)
Dr. M Guma noted @ACRheum 2022 Guidelines on RA recommend the #MediterraneanDiet; studies have shown this diet reduces CV risk, RA disease activity #RNL2024 @RheumNow https://t.co/AdKWgME4nD

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TheDaoIndex KDAO2011 ( View Tweet)
#RNL2024 @RheumNow 2022 ACR Guideline for Integrative Interventions for RA - Conditionally recommend Mediterranean diet - Conditionally recommend Against other diets or dietary supplements *Low or very low to moderate evidence due to absence of good studies 🍇🫒 https://t.co/PkZ9ovQ1ON

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Eric Dein ericdeinmd ( View Tweet)
ICYMI: We have an ACR guideline for diet! Luckily, you're likely already recommending the Mediterranean diet (conditionally recommended.) https://t.co/7W1ZIpqo47 Dr. Monica Guma #RNL2024 @RheumNow

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Dr. Rachel Tate uptoTate ( View Tweet)

ICYMI There are 2022 Guidelines for exercise rehab and diet for patients with #RheumatoidArthritis found here https://t.co/PWjPHGqqeM #RNL2024 @RheumNow

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TheDaoIndex KDAO2011 ( View Tweet)

#Cardiorheumatology is an emerging, important field; contact Dr. Weber if interested in learning more. #RNL2024 @Rheumnow https://t.co/WhMlC7AtHU

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TheDaoIndex KDAO2011 ( View Tweet)
#RNL2024 @RheumNow ASCVD Risk Calculators underestimate risk in patients of RA Inflammatory disease was added as a "risk enhancer" in 2019 update "A low ASCVD and/or absence of symptoms may be not be reassuring" https://t.co/XjTuzvvO4v

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Eric Dein ericdeinmd ( View Tweet)
Why is improved plaque identification important? 1. Most stress tests are normal! 2. Most events occur in pts with normal function studies 3. Plaque burden predicts risk, better than stenosis Dr. B. Weber #RNL2024 @RheumNow https://t.co/Qs19qIYj5v

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Dr. Rachel Tate uptoTate ( View Tweet)
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