A Microneedle Pill as an Alternative to Injectable Drug

Save

Carl Schoellhammerhas just won the Lemelson-MIT National Collegiate Student Prize for his invention - the microneedle pill.

Adalimumab Gets FDA Orphan Drug Status for Use in Hidradenitis Suppurativa

Save

The FDA has granted adalimumab (Humira) orphan drug designation for the investigational treatment of moderate-to-severe hidradenitis suppurativa (HS) (Hurley Stage II and Hurley Stage III disease).

Early DMARD Therapy Averts Cardiovascular Risk in RA

Save

A Finnish early RA register studied 14,878 incident RA patients from 2000-2008 and identified 1157 deaths.  Patients receiving DMARDs and MTX had lower mortality rates. The standardized moratility ratio for the entire cohort was reduced (0.57, 95% CI 0.52 to 0.62).

Communication Gap Between MDs and Lupus Patients

Save

May 10 was World Lupus Day.

Economic Impact of Biosimilars

Save

According to the Federal Trade Commission biosimilars have the potential to save the U.S. healthcare system $250 billion through 2022.

Hepatotoxicity and TNF Inhibitors

Save

Hepatic enzyme elevations with TNF inhibitor use is not uncommon.

RA Compliance Undermines Treatment Success

Save

Researchers at MD Anderson Cancer Center in Houston prospectively studied 107 RA patients with regard to oral medication (DMARDs, steroids) adherence. They report that adherence was low, ranging from 58-71% overall.

Zoster Risk is Similar Among Different MOA Biologics

Save

The risk of new H zoster infection was studied among nearly 30,000 new biologic starts and compared rates seen with abatacept, adalimumab, rituximab, infliximab, etanercept, tocilizumab, certolizumab or golimumab initiation.

AS vs. SpA Responses with Combination Treatment

Save

Patients in a large Swedish registry with ankylosing spondylitis (AS) and spondyloarthritis (SpA) who started a TNF inhibitor were followed for comedication use and TNF inhibitor survival.

Comorbidities Abound in Fibromyalgia

Save

Fibromyalgia is a highly prevalent disorder with different studies and populations showing a prevalence of 2.1% to 6.4% in the general population.  A retrospective review from Olmstead county revealed that among 1

Communication is the Best Medicine

Save

Patients rate communication as one of the most important factors in choosing and sticking with a physician. The end product in at least 2/3 of visits is the prescription, yet prescription adherence is substandard in half of our patients. The key is communication.

The Risk of Listeriosis in RA

Save

In the mid-1990s, our Rheumatology Division at the University of Texas Southwestern Medical School became involved with an early trial of a brand new TNF inhibitor.

Medical Marijuana for Osteoarthritis in Illinois

Save

An advisory board has recommended osteoarthritis and a host of disorders for inclusion in the Illinois new medical marijuana program.

Most Prescribed Branded Drugs Through March 2015

Save

In the last 12 months, levothyroxine (Synthroid) was the most prescribed drug in the USA  with 21.6 million prescriptions. Adalimumab (Humira) had 8.3 billion in sales, followed by etanercept (Enbrel) at nearly $6 billion. 

Who Should Pay for Drug 'Take-Back' Programs

Save

Unused pills and prescriptions pose a significant safety risk in the home and may contribute to dosing errors or inadvertent drug use. The issue has led the DEA to sponsor national drug disposal programs and local municipalities have followed with similar programs. At issue is who shoul

Drug-Induced Lupus is Rare with TNF inhibitor Therapy

Save

Real World Biologic Success in Systemic JIA

Save

A retrospective review of 77 SoJIA patients revealed that 50-70% achieved inactive disease or remission when treated with IL-1 inhibitors (anakinra, canakinumab). Good responses were seen with tocilizumab or abatacept, but only 8% responded to etanercept.

Medicare Spends $2.5 billion on Prescription Nexium in 2013

Save

Medicare released its list of the most costly medicines presribed in 2013.

The Science and Faith of Herpes Zoster Management

Save

Celebrex Goes Generic

Save

The generic drug manufactuer Actavis joins Teva and Mylan with their lauch of celecoxib (Celebrex)in 50 mg, 100 mg, 200 mg and 400 mg capsules. In 2013 celecoxib was the 21st leading prescribed drug in the U.S. with $2.4 billion in sales as of mid 2014.