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Article

Autoimmune Risk of Death Up during COVID

Jack Cush, MD

A population-based study in the UK shows that patients with rare autoimmune rheumatic diseases (RAIRD) were 44% more likely to die during the 2020 COVID-19 pandemic (March - April) compared to either the general population or their pre-COVID risk.

Article

MDA-5 Antibodies and Juvenile Dermatomyositis

Jack Cush, MD

A multicentre, retrospective study examined MSA profiles (by immunoprecipitation) from 96 juvenile idiopathic inflammatory myopathies (JIIM) at nine pediatric rheumatology centres in Japan. MSA were found in 85 of 96 cases with over 90% of patients having one of the following three MSA

Article

Higher Lupus Mortality Among Minority Populations

Jack Cush, MD

The February 19th MMWR reports that higher mortality rates in certain patients with systemic lupus erythematosus (SLE); data based on recent San Francisco County statistics showing a four fold higher mortality among Asian and Hispanic/Latina females with SLE.

Dr. John Cush Tweet
RheumNow
Study of 207 Pediatric pts treated w/ Rituxan (for Rheum, Cancer, CNS, Renal dz) and 40% developed hypogammaglobulinemia post-RTX; hypo-IgG Pre-RTX 28.7% to Post RTX 42.6%, p=0.009; low IgG levels had higher risk of serious infx (OR 2.3) https://t.co/b91rPYgVV2
Dr. John Cush Tweet
RheumNow
In the UK, NICE has recommended Kineret (anakinra) for use as 1st line biologic Rx in systemic JIA and adult-onset still’s disease (AOSD); but pts must first fail a DMARD - the latter is unfortunate as systemic Sxs of Still's do not respond to usual DMARDs.https://t.co/BNdqhLy9jg
Dr. John Cush Tweet
RheumNow
Analysis of 8416 pts w/ Kawasaki disease (KD) shows older and younger children differ. <10% were under 6 mos, 78%) were 6 mos-4yrs; 11% 5 to 9 yrs. Younger KD had more incomplete KD, coronary aneurysms, while older had more delayed diagnoses, more fever https://t.co/NkSmfg38ru
Dr. John Cush Tweet
RheumNow
Common mucocutaneous findings in 35 kids w/ MIS-C & COVID: 1) conjunctival injection (21), palmoplantar erythema (18), lip hyperemia (17), periorbital erythema/edema (7), strawberry tongue (8), & malar erythema (6) https://t.co/mcSOXtXaEh
Dr. Rachel Tate Tweet
uptoTate
1975: Nixon & Bresnev, in effort of medical diplomacy, cooperated on JRA trials. (Fact: Stalin's personal physician was a rheumatologist.) Dr. Steven's shares an interesting historical slide about this collaboration. #RWCS2021 #RWCS @RWCSmtg @RheumNow https://t.co/Px71qfqDcy
Dr. Rachel Tate Tweet
uptoTate
Some statistics regarding pediatric rheumatologists in the US and abroad. Here in the US we have under 30 fellowship options, 448 pediatric rheumatologists in 2019 (and growing), and patients/families are driving on ave 42.8 miles to get care. #RWCS2021 #RWCS @RheumNow @RWCSmtg https://t.co/RhTroEKcwN
Dr. John Cush Tweet
RheumNow
A serious shortage of pediatric rheumatologists in the USA, where we need at least 1 ped rheum per 400,000 population. @RWCSmtg https://t.co/o8XCkjUOaN
Dr. John Cush Tweet
RheumNow
Dr. Anne Stevens lecturing at @RWCSmtg on the history of pediatric Rheumatology. Sir Eric Bywaters was the Father of meeting day pediatric Rheumatology @RWCSmtg https://t.co/iZtPfgoyxa
Dr. John Cush Tweet
RheumNow
Dr George F Still, among the first to write about children with arthritis, pediatric Rheumatology, in 1898, with his description of 22 kids with arthritis. @RWCSmtg https://t.co/Y6DOzooFjZ
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