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COVID Virus Persistence with DMARD Use

MedPage Today

Drugs commonly used to treat systemic autoimmune rheumatic diseases (SARDs) may keep the SARS-CoV-2 circulating after COVID-19 infection in patients with these conditions, with researchers documenting substantially increased viral antigen persistence compared with other post-COVID patients.

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Review of GLP-1 Receptor Agonists in Psoriasis

Jack Cush, MD

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have transformed cardiometabolic medicine and are now attracting intense interest in inflammatory disorders.

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Tavneos

FDA Targeting the Safety of Avacopan

Jack Cush, MD

The future of avacopan is up in the air. In April, the FDA issued a drug safety warning, previously requesting that Amgen to pull its rare disease drug Tavneos from the market. Now, there appears more pressure to remove it from the market.

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exercise,group

EULAR Recommendations for Physical Activity in Arthritis

Jack Cush, MD

EULAR has published a 2025 update for physical activity recommendations for patients with osteoarthritis (OA) and rheumatoid arthritis (RA). 

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STEROIDS COVER

Steroids

Jack Cush, MD

In this Advanced Practice Rheum, Dr. Jack Cush reviews steroids.

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Switch or Cycle - Upadacitinib vs Adalimumab in Refractory RA After the first tumor necrosis factor inhibitor (TNFi) failure, patients with active rheumatoid arthritis (RA) responded by switching to upadacitinib, compared to cycling to a second TNFi, adalimumab. https://t.co/mEaUcBD2ZK
Dr. John Cush RheumNow ( View Tweet)
Mexico study of SLE mortality in kids. Betw 2000-23, SLE accounted for 637/280,334 child deaths. Females (80%) had 4X higher deaths than males (ASMR 0.13 vs 0.03). No consistent trend in time for mortality. https://t.co/gkoXG90nLx https://t.co/BB0JhTHFKf

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Dr. John Cush RheumNow ( View Tweet)
A man spends 50 years teaching at MIT. He knows his time is running out. So he records one last lecture — everything he knows, distilled into a single hour. He died 5 months later. This is that lecture. The most important hour you'll watch this week. 👇 Bookmark it for later https://t.co/tRUH05ysSt

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Suryansh Tiwari Suryanshti777 ( View Tweet)
APR: Methotrexate Companion slide deck for the Advanced Practice Rheum: Methotrexate video, featuring Dr. Jack Cush. https://t.co/8422FKN4dq https://t.co/6gVS7dA8Gi

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Dr. John Cush RheumNow ( View Tweet)
True or False: Low-dose aspirin given at giant cell arteritis diagnosis is associated with a lower risk of major adverse cardiovascular events. Put your answer to the test in the latest RheumIQ quiz at https://t.co/XLPVoyCbLB. https://t.co/C5CSwuv5mF

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Dr. John Cush RheumNow ( View Tweet)
Study of 216 RA pts - Serum IL-8 independently assoc w/ RA Dz activity. CRP & IL-6 significantly associated w/ higher IL-8 levels, but RF & CCP did not. IL-8 also correlated w/ CV risk (SCORE2) & carotid intima media thickness https://t.co/aqUoAeXFFP https://t.co/ZW7OAx8YGK

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Dr. John Cush RheumNow ( View Tweet)
Dental study from India assessed periodontal Dz (PD) in 170 RA vs 170 non-RA pts. RA had more PD, ^ESR, more mild PD (39% v 29%). DAS-28 correlated w/ PD severity. Pts w/ periodontitis had 3X ods of RA (OR = 2.9) /https://t.co/bvOnFzbRcd https://t.co/cSxfiIR4iS

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Dr. John Cush RheumNow ( View Tweet)
Follow the Money (4.23.2026) Dr. Jack Cush follows the money and all the news that fits the Rheumatology Gab for this past week. https://t.co/nEWINTOw6L https://t.co/a4oZxqwYhv

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Dr. John Cush RheumNow ( View Tweet)
True or False: The DESIR axSpA cohort study found a significant association between NSAID use and incident hypertension over 10 years. See if you got it right in the latest RheumIQ quiz at https://t.co/N5rfozh757. https://t.co/tkj0na3bkh

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Dr. John Cush RheumNow ( View Tweet)
The impact oif obesity on the immune system. Through methylation, obesity imprints memory to CD4+ (helper) T cells, which can last for many years, and promotes immune system dysregulation and inflammation. @emboreports https://t.co/j2tASpZlE0 https://t.co/5CgUrsFZru

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Eric Topol EricTopol ( View Tweet)
APR: Difficult to Treat RA Companion slide deck for the Advanced Practice Rheum: Difficult to Treat Rheumatoid Arthritis video, featuring Dr. Jack Cush. https://t.co/GXnTicNTL6 https://t.co/ojOsMZ4sA7

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Dr. John Cush RheumNow ( View Tweet)
Are uveitis and psoriasis independently associated with greater spinal radiographic progression in ankylosing spondylitis? Test your knowledge in the latest RheumIQ quiz at https://t.co/N5rfozh757 https://t.co/PjY1iuLv0X

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Dr. John Cush RheumNow ( View Tweet)

Danish registry study of truncal (2,260) vs superselective (3,810) vagotomy (1977-95) vs general popul. (10:1). Truncal incr. RA risk (aHR 2.62), but selective did not (aHR 1.05. Neither had effect on OA risk https://t.co/dqejtN9TwY https://t.co/R0OJZTxd5T 

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Dr. John Cush RheumNow ( View Tweet)
Sun Pharma buys out Organon w/ $11.75 billion buyout. Both generated $6.2 billion in 2025 sales. Organon spun off from ‌Merck in 2021, specializes in women’s health and is top 7 in biosimilars. Sun is into dermatology, ophthalmology and oncology-dermatology. https://t.co/zb4hucTqCJ
Dr. John Cush RheumNow ( View Tweet)
Presented at AACE Annual Meeting, FREEDOM Real-World Study looked atypical femoral Fxs & found a low AFF risk - 24 AFFs w/ denosumab (0.89/1KPY) vs 397 AFFs w/ bisphosphonates (0.82/1KPY) but no active comparators & excluded pts w/ comorbidities. https://t.co/vRwkfHSXxh https://t.co/xzgC0D5ZTu

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Dr. John Cush RheumNow ( View Tweet)
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