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Neuropsychiatric SLE - 2/3 Improved at 12 Months
The management and outcomes of neuropsychiatric systemic lupus erythematosus (NPSLE) can be challenging as there is limited data.
Best Imaging in Giant Cell Arteritis - US, PET, MRI?
Imaging is often instrumental in diagnosing and staging patients diagnosed with giant cell arteritis (GCA).
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Seasonal Pathogens and Henoch-Schönlein Purpura
Epidemiologic studies of Henoch-Schönlein purpura (HSP) have suggested seasonal variation in occurrence rates (higher from September-April, lower in June-August), suggesting a role for infectious triggers.
https://t.co/MmuVVziqv8 https://t.co/PhidOFTbFV
Dr. John Cush RheumNow ( View Tweet)
Pearl: Patients with persistent TMJ pain are more likely to have fibromyalgia than inflammatory or degenerative arthritis (as the underlying cause of their chronic pain) https://t.co/gCEm8A3RAT https://t.co/bvK2ii4fXP
Dr. John Cush RheumNow ( View Tweet)
IL-1 recept accessory protein (IL1RAP) shown to block mediators (IL-1, IL33, IL36) that may drive systemic sclerosis. In vitro, IL1RAP inhibited fibroblasts and endothelial cells; in mouse models of SSc anti-IL1RAP decr dermal & pulmonary fibrosis. https://t.co/jWjUMKdqGw https://t.co/O3o5iDHD6X
Dr. John Cush RheumNow ( View Tweet)
ICYMI: Top 5 Clinical Pearls in RA Management
https://t.co/DphF8HcuHD https://t.co/CF9UuBCUxS
Dr. John Cush RheumNow ( View Tweet)
SLE in JAMA (authored by Drs Siegel & Sammaritano at HSS), impressive, full-read review, Covers:
- Presentations: skin, Jts, brain, heme, etc
- Treatments
- Prognosis
- Complications: CV, infx, CA
- FAQs
https://t.co/TPkm3BlrSw https://t.co/FqN1ZXyv4Y
Links:
Dr. John Cush RheumNow ( View Tweet)
JAMA: SLE Review
Drs. Caroline Siegel and Lisa Sammaritano (from HSS in NYC) have published an impressive overview of systemic lupus erythematosus (SLE) in JAMA. This timely, well-written review covers the many complexities of this multi-organ disorder that affects nearly 3.4 million people worldwide.
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1/600 Falls May Die (4.5.2024)
Dr. Jack Cush reviews the news and Journal reports from this past week on RheumNow- including problems w/ falls, pain and treatment of Dupuytren’s contractures.
https://t.co/37JSS1fbLi https://t.co/WEwjntAQEt
Dr. John Cush RheumNow ( View Tweet)
Serious Infections in Takayasu arteritis
The large vessel vasculitis, Takayasu arteritis (TAK), carries a significant morbid risk and a cohort analysis shows these patients are also at high risk of serious infection with resultant higher risk of death.
https://t.co/qqtpCMYnZf https://t.co/ZlxATKVQIA
Dr. John Cush RheumNow ( View Tweet)
Canadian OBRI study in 692 RA pts shows pts treated w/ triple DMARD (MSH) stayed on Rx longer (15 mos) compared to MTX+LEF (9.6 mos); not significant but MTX/SSZ/HCQ had signif lower DAS28 @ 6 mos (3.4 vs 3.9) & at 12 mos (3.2 vs 3.5, p=0.0005) https://t.co/tuIigaswDK https://t.co/DAh3lgRufA
Links:
Dr. John Cush RheumNow ( View Tweet)
Primary care pop. study pts shows poor health literacy in gout pts assoc. w/ more gout flares. Study of 551pts; 30% w/ 2+ flares in 12 mos; 9.4% w/ poor health literacy. pts had more flares (OR 4.1) & hx of oligo/polyarticular flares (OR 1.93) https://t.co/tDiFqixbLV https://t.co/Kb75iJwTZE
Dr. John Cush RheumNow ( View Tweet)
#RNL2024 @RheumNow
@AlexisOgdie
Many therapies for SpA - but ONLY TNFi, IL17i, and JAKi for AxSpA
Check out https://t.co/3918uYvdFj to help guide treatment decisions: Prior therapies? enthesitis? concomitant IBD/uveitis? comorbidities? Pt preferences? https://t.co/6ugueBPMTy
Dr. John Cush RheumNow ( View Tweet)
#RNL2024 @RheumNow
@AlexisOgdie
Many therapies for SpA - but ONLY TNFi, IL17i, and JAKi for AxSpA
Check out https://t.co/3918uYvdFj to help guide treatment decisions: Prior therapies? enthesitis? concomitant IBD/uveitis? comorbidities? Pt preferences? https://t.co/6ugueBPMTy
Links:
Dr. John Cush RheumNow ( View Tweet)
TAPIR study shows that GPA patients treated with rituximab can be safely weaned off low dose prednisone. But. 20% risk of relapse in those treated with non-RTX regimens @VasculitisBCN24 #vasculitis https://t.co/jDy0lOQQIP
Catherine Hill CatherineL_Hill ( View Tweet)
Human touch. A systematic review that underscores the physical and mental health benefits. The essence of medicine that will not be provided by #AI
https://t.co/OvCDJYAsoS @NatureHumBehav @j_packheiser @helenahhartmann
@FredericMichon @GazzolaValeria @sbl_nin https://t.co/YuAiKtq87p https://t.co/Sxj1LfO5ZG
Eric Topol EricTopol ( View Tweet)
Human touch. A systematic review that underscores the physical and mental health benefits. The essence of medicine that will not be provided by #AI
https://t.co/OvCDJYAsoS @NatureHumBehav @j_packheiser @helenahhartmann
@FredericMichon @GazzolaValeria @sbl_nin https://t.co/YuAiKtq87p https://t.co/Sxj1LfO5ZG
Eric Topol EricTopol ( View Tweet)
Human touch. A systematic review that underscores the physical and mental health benefits. The essence of medicine that will not be provided by #AI
https://t.co/OvCDJYAsoS @NatureHumBehav @j_packheiser @helenahhartmann
@FredericMichon @GazzolaValeria @sbl_nin https://t.co/YuAiKtq87p https://t.co/Sxj1LfO5ZG
Eric Topol EricTopol ( View Tweet)
Expert Review
Rheumatoid Arthritis: The Continuum of Disease and Strategies for Prediction, Early Intervention, and Prevention
📰 https://t.co/JfkO8WpELc
#rheumatoidarthritis #prediction #prevention https://t.co/3xqHalhjCV
The Journal of Rheumatology jrheum ( View Tweet)
Expert Review
Rheumatoid Arthritis: The Continuum of Disease and Strategies for Prediction, Early Intervention, and Prevention
📰 https://t.co/JfkO8WpELc
#rheumatoidarthritis #prediction #prevention https://t.co/3xqHalhjCV
The Journal of Rheumatology jrheum ( View Tweet)