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COLCHICORT Trial

Jack Cush, MD

The COLCHICORT trial in acute calcium pyrophosphate (CPP) crystal arthritis patients showed that colchicine was inferior to prednisone treatment and that responses were also influenced by other factors.

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Sjögren's Graduates (8.22.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news, journal reports, FDA approvals, drug safety, and more from this week.

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A New RA Approval (8.1.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news, journal reports and a new treatment for RA from the FDA.

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NHANES, Numbers, & Risk (7.18.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com along with interesting case questions from "Ask Cush Anything".

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Hmmm Really? (7.11.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from this past week - some obvious, other new thoughts and some - hmmm, reallly?

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ICYMI: Proinflammatory Diet Increases Gout Risk

MedPage Today

Some dietary habits are worse than others when it comes to gout risk for women, a large study indicated. Data from the two iterations of the Nurses' Health Study, in which more than 170,000 women were followed for more than two decades, indicated that diets scoring high on the Empirical Dietary Inflammatory Pattern (EDIP) index nearly doubled the risk for new-onset gout after adjusting for body mass index.

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Nurse-Led Treat-to-Target Clinics

EurekAlert!

New studies shared at the 2025 annual EULAR congress in Barcelona highlight the benefits that nurse-led care can bring for both patients and healthcare systems.

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Colchicine for #gout patients with CV risk: - since it has a purely anti-inflammatory effect, risk of acute CV events in pts w/ high CV risk is reduced. vs. NSAIDs/steroids, colchicine remains to be a safer option for gout prophylaxis @rheumnow #APLAR25 https://t.co/WgfTcIleMd

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sheila RHEUMarampa ( View Tweet)
SGLT2 inhibitors exert their anti-inflammatory effects by inhibiting activation of the NLRP3 inflammasome. Secondary analyses of RCTs show that SGLT2is can reduce the risk of incident #gout @RheumNow #ACR25 https://t.co/IWgyDYEQoZ

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sheila RHEUMarampa ( View Tweet)
Gout Education Card for Patients - Info & Rules #1 https://t.co/uppST8OBLZ https://t.co/3Ry3erNJCL

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Dr. John Cush RheumNow ( View Tweet)
Gout Education Card for Patients - Diagnosis & Management #2 https://t.co/uppST8OBLZ https://t.co/sLF5WPeuA5

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Dr. John Cush RheumNow ( View Tweet)
RA & GOUT? S. Korean study of 34,356 new RA pts vs 103,068 controls. RA had 2.7 X higher risk of gout vs non-RA. Seropos & Seroneg equal incr risk (aHR 2.8 & 2.6), slightly higher in SPRA(aHR 1.07). RA on b/tsDMARDs had lower risk (aHR, 1.93) vs Untreated (aHR, 2.78). https://t.co/P0oqq5bVnq
Dr. John Cush RheumNow ( View Tweet)
NEJM images: 55-year-old man with metastatic squamous-cell lung cancer Hx& 6-wk Hx firm, painful swelling RToe1 & RDIP3 w/ ulceration. Xray showed lytic lesions due to acrometastases - rare bony metastases distal to elbow or knee, that may may mimic gout or osteomyelitis https://t.co/1Fh1Cp9dm9
Dr. John Cush RheumNow ( View Tweet)
Rheums! Question or case for Jack Cush? Record it here and we may feature it on an upcoming podcast. https://t.co/HsqM9xLNtP https://t.co/voONsOLeSK

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Dr. John Cush RheumNow ( View Tweet)
Global burden of dz study - UN statistics show post-Menopausal women (PMW) are 20% of all women in 2021 (vs 13.7% 1990). From 1990 to 2021, the prevalence of MSK Dz in PMW significantly risen, especially for RA, OA, and gout. https://t.co/HdkopkxLdv https://t.co/wsGhg0P1tL

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Dr. John Cush RheumNow ( View Tweet)
New ideas in gout management Gout flares are associated with cardiovascular events. Treating gout to target serum urate level prevents flares, but whether such treatment can also prevent cardiovascular events is unknown. https://t.co/C8G39JzP9Y https://t.co/NAClL0JLGX

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Dr. John Cush RheumNow ( View Tweet)
Multinational metanalyses of 24 studies & 1,173,410 participants shows alcohol increases risk of hyperuricemia (OR 1.51) and gout (OR 1.81) - more so in males > females. Little effect of age, country, study type, type of alcohol, Dx criteria in regression analyses. https://t.co/NSYTppcKzV
Dr. John Cush RheumNow ( View Tweet)
The ‘iron fist’ of haemochromatosis arthropathy, and other key features: Patrick Kiely #EULAR2025 @RheumNow https://t.co/grs1Tq3GAk

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David Liew drdavidliew ( View Tweet)
1st #recommendations for #Hemochromatosis #arthropathy #psuedogout #CPPD #calcium #pyrophosphate #arthritis #EULAR2025 #Recommenadations II @RheumNow @eular_org https://t.co/AnE4T2wYoa

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Janet Pope Janetbirdope ( View Tweet)
URAT1 inhibitors look like the way to go in Gout! Presented in multiple abstracts at #EULAR2025 Pozdeutinurad Ph2 long term safety data chronic gouty arthritis + tophi OP0300 Ph3 RCT of Ruzinurad in hyperuricemia/primary gout OP0302 Ph 2b RCT of SAP-001 Refractory Gout +/-

Aurelie Najm AurelieRheumo ( View Tweet)

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