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Day 3 EULAR Report
Day 3 was an interesting mix of posters, oral presentations, and review sessions on many practical subjects like osteoarthritis, large vessel vasculitis, systemic sclerosis, and pregnancy. Here are a few of my recommended abstracts from Friday at EULAR 2026.
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5 years since Patient ID001: Progress on CAR-T Therapy in RMD
Five years on, are we closer to licensing of the first CAR-T therapy in rheumatic and musculoskeletal diseases (RMD)?
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Failure to achieve early remission RA asso w/ non-inflammatory pain
NORD-STAR 526 early RA pts)
no remission at 24 wks increased risk of 48wk
• unacceptable pain (OR ~6)
• refractory pain (OR ~6)
• fibromyalgic RA (OR ~16)
Signal strongest w/ very early remission wk8 https://t.co/H8iyhIrsJw
Aurelie Najm AurelieRheumo ( View Tweet)
Even with tight T2T, ARCTIC 10yr follow-up (n=170) show 9% had RA-ILD on HRCT, plus another 19% with non-specific interstitial findings. Male sex and older age were risk factors. Seropositivity was not. Vigilance remains essential. @RheumNow #EULAR2026 POS1270
Jiha Lee JihaRheum ( View Tweet)
#EULAR2026 Recommendations: Vasculitis
-Confirm diagnosis with imaging and biopsy
- Start GC early but with taper plan
- For major flare again confirm dx and restart GC
- Consider IL-6 or UPA
- MTX may be option if biologics not available
@RheumNow https://t.co/DqLZtW630y
Jiha Lee JihaRheum ( View Tweet)
#EULAR2026 POS1355 A cohort study in Japan identified 5-score predictors of GC-free remission in #lupusnephritis: HCQ, pulsed IV GC, Chronicity index=0, =>75% UPCR reduction by 6mo,& 12 mths CRR. Data cutoff 2024. Interested to see impact of current Combo tx from outset @RheumNow https://t.co/qmpgyEyOOV
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Core definitions when understanding vaccination.
@RheumNow #EULAR2026 https://t.co/wD0iTDxMEx
sheila RHEUMarampa ( View Tweet)
RheumNow’s expanded coverage of #EULAR2026 annual meeting is sponsored by Bristol Myers Squibb and UCB. RheumNow and its faculty independently select all coverage content.
Dr. John Cush RheumNow ( View Tweet)
Beyond the Scale: Do GLP-1RAs Offer More Than Weight Loss in PsA?
Over 70% of patients with psoriatic arthritis (PsA) struggle with excess weight, amplifying synovio-entheseal inflammation and blunting biologic response.
https://t.co/pAIXkdazci https://t.co/vQTn3BWv2r
Dr. John Cush RheumNow ( View Tweet)
CT imaging in RA
Body composition changes beyond BMI
489 RA vs 397 ctrl
RA asso w/
-increased subcutaneous fat
-increased intermuscular adipose tissue -poorer muscle quality
Looks like it represent “hidden obesity” with more by fat redistribution and myosteatosis
#OP0348
Aurelie Najm AurelieRheumo ( View Tweet)
And now does MRI do better than US at predicting RA progression in at risk pts?
Short answer: No likely too sensitive!
130 anti-CCP+ symptomatic pts
36.9% progressed
BL US positivity predicted progression HR 2.8
MRI showed prevalence of subclinical disease synovitis >80%
Aurelie Najm AurelieRheumo ( View Tweet)
Do probiotics help in #PsA? First RCT (MEDIPSA) says no. Multispecies probiotic vs placebo in 66 pts: 43% vs 65% achieved low disease activity at wk 12 (p=0.167). Gut-joint axis intriguing, but probiotics not the answer yet. @RheumNow #EULAR2026 POS0290
Jiha Lee JihaRheum ( View Tweet)
"It takes about a million dollars to get one AI algorithm approved"
So even after creating an Ai solution, its difficult to actually be able to use it in rheumatology.
@RheumNow #EULAR2026 https://t.co/yX6cT19Sdd
Bella Mehta bella_mehta ( View Tweet)
Detecting subclinica tenosynovitis in pts at risk for RA: who does it better US or DixonMRI?
65 pts RA CSA, US detected only ~23% of cases identified by Dixon
US misses most! But are they “real” tenosynovitis?
MRI (5-min, no contrast) higher sens
US higher spe
Shall we do https://t.co/stsMRdj9eY
Aurelie Najm AurelieRheumo ( View Tweet)
What does remission really mean to patients with #PsA? The RemiPPsA international qualitative study asked 123 patients across 11 countries. Pain-free + ability to resume daily life topped the list, not just composite scores. #EULAR2026 @RheumNow, POS0294 https://t.co/mEGpkewuTX
Jiha Lee JihaRheum ( View Tweet)
#EULAR2026 POS0172 #Lupus arthritis is the most common domain in RCTs but SLEDAI-MSK or BILAG-MSK isn’t satisfactory. Look out for the role out of LAMDA once externally validated using independent trial datasets. 4 candidates: SJC28, ESR, VAS Phy MSK, & VAS Pa Pain @RheumNow https://t.co/QJ51ETLSSN
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Emapalumab in MAS secondary to stills disease
39 pts, median age 12, 2 pooled prospective, open label, single arm studies.
Endpoint complete resolution at week 8-. Around 60% and partial resolution nearly 100%
67% had concomitant anakinra
@RheumNow ##EULAR2026 #EULARBest https://t.co/sGm43C3LfH
Links:
Bella Mehta bella_mehta ( View Tweet)
Lung US for RA-ILD screening
Comparison with diagnostic scores
147 RA pts (68 ILD on HRCT)
Asymptomatic cohort
Sens 95.4% Spe 77.7%
Risk scores alone performed poorly.
Combining US + risk scores boosted sensitivity to 100% → promising low-cost screening tool alongside HRCT. https://t.co/7C4zClaxry
Aurelie Najm AurelieRheumo ( View Tweet)
Can AI read 20 years of RA X-rays?
And how much faster/better than us?
20 years ESPOIR cohort 7500+ joints
RADAR algorithm
94–95% accuracy compared with expert readers
99% spe 93% sens
#OP0344 #EULAR2026 @RheumNow https://t.co/8hFHCY4SaY
Aurelie Najm AurelieRheumo ( View Tweet)
Diet as a DMARD? The Evidence Is Still Hard to Swallow
Dietary interventions are rarely taken as seriously as pharmacological therapies in rheumatology. Yet patients ask about them constantly, and an increasing number of studies suggest that nutrition may influence disease https://t.co/BLrr3CNZMg
Dr. John Cush RheumNow ( View Tweet)
