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Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com. How good (or not) are rheumatologists and what to do about MTX nodulosis?
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SPACE study of adults referred to rheumatology with less than 2 years of chronic back pain (CBP), shows that only one-third can be reliably diagnosed with axial spondyloarthritis (axSpA).
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The original randomized controlled, prospective MAINRITSAN study of 115 patients (87 with granulomatosis with polyangiitis, 23 with microscopic polyangiitis, and 5 with renal-limited ANCA-associated vasculitis [AAV]) demonstrated superiority of rituximab (RTX) over azathioprine (AZA) for maintenance of remission at 22 months in ANCA-associated vasculitis patients after CYC remission induction.
Dr. John Cush
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IL-17 pathway as a target in giant cell arteritis - full read review of pathogenic role of IL-17 and Th17 cells, in #GCA; backed up by the phase II proof-of-principle TiTAIN study showing potential efficacy of secukinumab in GCA pts https://t.co/MThzw2joGO https://t.co/PmrJjf9C3a
Dr. John Cush
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2023 EULAR Non-pharmacological Management of Hip and Knee Osteoarthritis: 2023 update
EULAR has published the 2023 updated recommendations for the optimal non-pharmacological management of hip and knee osteoarthritis (OA).
https://t.co/OjmdAnRWtl https://t.co/gfWYopEgtt
Dr. John Cush
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Japanese retrospective study compared RA pts on JAK inhib vs bDMARDs (n=62 ea) having orthopedic surgery; JAKi- pts had more postoperative flares (29% v 12%, P=.01), esp if JAKi held >11d (p.04). No diff in other postop complications https://t.co/NVY1Oajdve https://t.co/fwc9KWYZ9l
Dr. John Cush
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Retrospective cohort compared 6147 new PsA pts vs 23,999 contros PsA. The uveitis risk was significantly higher in PsA (adj HR 2.38). Uveitis risk in PsA higher with prior uveitis (adj OR 136.4) and etanercept Rx (aOR 2.57). 106/107 Rx w/ topical steroids https://t.co/YVzIzSOaiB https://t.co/YORU8cQrAx
Dr. John Cush
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Increased CV Comorbidity in Dermatomyositis
A cohort study suggest that patients with dermatomyositis (DM) are at an increased risk for multiple comorbidities, including chronic kidney and cardiovascular disease,
https://t.co/bYvd5AhqSl https://t.co/4y4kjYhTm3
Dr. John Cush
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Hepatitis B Virus Reactivation is possible w/ immunosuppression- most (>10%) w/ w/ Rituximab & stem cell transplants. If HBsAg positive, pts should recv anti-viral prophylaxis; HBsAg− individuals should be evaluated on a case-by-case basis https://t.co/7JKorgWbYr https://t.co/RdW65u5KDR
Dr. John Cush
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Metanlysis of 49 studies, 10 RCTs examined the relationship between RA and non-surgical Rx of periodontitis (NSRT) and in general short term studies show that NSPT benefits RA patients; and DMARD therapy benefits periodontitis https://t.co/Bw66VrIMp2 https://t.co/v9SG3sdeni
Dr. John Cush
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You can still attend RheumNow Live!
This 1.5-day long meeting offers pre-learning modules, shorter, concise lectures with clinical context and audience input, more discussion time, and sessions that are relaxed and comprehensive.
Register: https://t.co/8jzvDmjVek https://t.co/U10B7zyQdR
Dr. John Cush
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QD Clinic - RA, SSZ, & MI
RA with a myocardial inflarction - which DMARD?
https://t.co/FqnouGylMN https://t.co/KzmLctKZBI
Dr. John Cush
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QD Clinic - GCA & Steroid Weaning
Weaning steroids in chronic GCA patient
https://t.co/HtrzP43Ivr https://t.co/xZZlNmeqP1
Dr. John Cush
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CMS Final Rule on Prior Authorization Reforms
Prior authorizations and paperwork are killing medical providers; the good news is that a new CMS rule may lessen the burden.
https://t.co/bw4Mt06Zgz https://t.co/6B2TXSZuZO
Dr. John Cush
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Fertility and Rheumatoid Onset
British women whose capability of bearing children either started late or ended early -- were at increased risk for developing RA, compared with women with earlier menarche or later menopause, researchers found.
https://t.co/SwxTvntqY2 https://t.co/bmwrLWwtke
Dr. John Cush
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Network meta-analyses of 153 trials & 8713 patients w/ chronic pain from TMJ disorders; Most effective (pain & function) were CBT, PT-assisted jaw mobilisation, trigger point injx, jaw exercise/stretching, manipulation, & acupuncture https://t.co/b4kTuWg9QH https://t.co/7SJs0sLtK2
Dr. John Cush
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You can still attend RheumNow Live!
This 1.5-day long meeting offers pre-learning modules, shorter, concise lectures with clinical context and audience input, more discussion time, and sessions that are relaxed and comprehensive.
Register: https://t.co/iWiFunwbNH https://t.co/3HmR7qqTMT
Dr. John Cush
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Data from the American Rheumatology Network (2014–2021) shows that among 15182 new TNFi initiations, only 45% had a dz activity measure (CDAI/RAPID3); and of these, only 47% had a TJC, SJC or pain score. Can you treat HTN without measuring BP? https://t.co/SsnF7Taky1 https://t.co/LN72IAWs8n
Dr. John Cush
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Tic-Borne Disorders Causing Chronic Arthritis?
Findings from a population based cross-sectional study suggests that while up to 20% of patients have antibodies to tick-borne exposures, only a minority reported musculoskeletal symptoms.
https://t.co/FWhCl3v8oH https://t.co/NDgvKYva11
Dr. John Cush
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New download available!
Seasonal Flu Vaccination in RA Patients
https://t.co/pLz8yo28QM https://t.co/7rKymy79jI
