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Drug-Induced Lupus is Rare with TNF inhibitor Therapy
Drug-induced lupus (DIL) has been associated with all TNF inhibitors. Early rates suggested this may be between 0.04 - 0.06 events per 100 patient-years or roughtly 5 per 1000 patient-years.
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Real World Biologic Success in Systemic JIA
A retrospective review of 77 SoJIA patients revealed that 50-70% achieved inactive disease or remission when treated with IL-1 inhibitors (anakinra, canakinumab). Good responses were seen with tocilizumab or abatacept, but only 8% responded to etanercept.
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