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Social Media Questions (7.29.2022)

d Jack Cush, MD

Dr. Jack Cush reviews the news, journal reports and rheumatologist cases from the past week on RheumNow.com. This podcast is brought to you by StillsNow.com - be sure to sign up for our monthly StillsNow email and Monthly StillsNow Podcast.

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Lungs ILD

Approach to ILD in Myositis Syndromes

d Jack Cush, MD

Mehta et al have published a full read review of managing interstitial lung disease (ILD) in patients with inflammatory myopathies, a heterogeneous group of syndromes connected by ILD and and increased morbidity and mortality risk.

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Fever,temp,man,HA,thermometer

Rheumatic Causes for Fever of Unknown Origin

d Jack Cush, MD

Fever of unknown origin (FUO) represents a diagnostic challenge to many physicians and while cancer and infectious causes need to be excluded, rheumatic disorders are amongst the most common causes of FUO.

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blood, level, numbers, data, calculation

Best Labs for Still’s Disease

d Jack Cush, MD

There is no “test” (blood or other) that is solely diagnostic of Still’s disease, but labs can help make a diagnosis or manage disease, and affirm the safety of drugs in use. ​​​​​​​ 

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I had the chance to discuss intrinsic protection from Covid with my friend @ASlavitt https://t.co/dI993XBoXr https://t.co/lidQnzgjJg

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Eric Topol EricTopol ( View Tweet)

Have the trends started to change in awards for more junior people in rheumatology? https://t.co/0UC9BvXfsY

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Rheum Cat rheum_cat ( View Tweet)

15 Powerful Visuals About Psychology & Life 1. https://t.co/ZY6QwhA9bK
Philosophy Pathfinder PhilosophyPath ( View Tweet)
Our commentary on the SELECT-AXIS 2 trial is also available: https://t.co/dkB2h6OeKJ @Spondy_MD https://t.co/GIDXVnhHcz

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Rheum Cat rheum_cat ( View Tweet)

Get insights to difficult to treat rheumatoid arthritis #D2T from the experts👉 This report summarizes what we know and what we still need to know! https://t.co/Qdkcu0Z2sk https://t.co/FW5rvSK1vi

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ARD & RMD Open ARD_BMJ ( View Tweet)
Best Labs for Still’s Disease There is no “test” (blood or other) that is solely diagnostic of Still’s disease, but labs can help make a diagnosis or manage disease, and affirm the safety of drugs in use. What tests should you be ordering? https://t.co/24QSfEEVwG https://t.co/bdrvSBd652

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Dr. John Cush RheumNow ( View Tweet)
The Johns Hopkins Hospital has repeated its top rank among US Rheumatology centers - ranking #1 for the 18th year in a row, according to U.S. News & World Report’s 2022–23 Best Hospitals list. https://t.co/dC5vVEhCrC https://t.co/skXbg1fAve

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Dr. John Cush RheumNow ( View Tweet)
Study of 63 Thalassemia pts (50 transfusion dep) w/ 22% α-, 73% β-, 5% α- & β-thal. 23 had inflammatory rheumatic Dz (IRD: RA 9, gout 6, SLE 3, SpA 2). ANA+ in 10% w/o IRD & Transfusion Dep had more + tests for direct Coombs & ANA https://t.co/QW6ecv98F1 https://t.co/GO3xC86hLc

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Dr. John Cush RheumNow ( View Tweet)
TREAT EARLIER Study - Is MTX Intevention in Pre-Clinical RA Warranted? https://t.co/rGcm1DSwJk https://t.co/paBrJVMXdP

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Dr. John Cush RheumNow ( View Tweet)
Belimumab (Benlysta) has been FDA approved for use in pediatric patients with active lupus nephritis who are receiving standard lupus therapy. The approval in kids is for the IV formulation only; SC belimumab is for SLE and LN in adults https://t.co/LCUFDpZM6j https://t.co/R2kA2DbxKy

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Dr. John Cush RheumNow ( View Tweet)
Metanalysis of cardiovascular effects of Colchicine: 21 RCTs (15,569 pts shows colchicine was superior to placebo reducing CV events; with lower risk recurrent pericarditis (RR 0.50), MACE (RR 0.67), & AFib recurrence (RR 0.68) https://t.co/oQEF7dmkH8 https://t.co/P7IKeZpcUB

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Dr. John Cush RheumNow ( View Tweet)
Single center, retrospective chart study shows that in 168 PsA patients, 26% were assessed within 6wks of referral. Median wait time = 78.5 d. The most common cause of delay was the lack of available spots in the PsA clinic. https://t.co/FDfFgxHhLD https://t.co/CYoT1PBp8l

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Dr. John Cush RheumNow ( View Tweet)
No Risk of RA w/ coffee consumption -- Swedish EIRA study, included 2184 early RA pts. High Coffee (>6 cups/day) was assoc w/ increased RA risk (OR 1.50;1.20–1.88) that was lost after adjusting for smoking (OR 1.14;0.89–1.45). https://t.co/3SIeHD4fII https://t.co/NqkjmuzSaV

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Dr. John Cush RheumNow ( View Tweet)
Nintedinib’s Durable Efficacy in Systemic Sclerosis Patients with interstitial lung disease (ILD) related to systemic sclerosis continued to see less progression when treated with nintedanib (Ofev) in the pivotal 100-week SENSCIS trial, researchers said. https://t.co/7rUuB6RRow https://t.co/MqBjOj1myW

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Dr. John Cush RheumNow ( View Tweet)
Metanalysis of 13 trials of corticosteroids (CS) in hand #OA shows no significant effect of intra-articular CS for CMC1 OA (pain or function); but medium effect of oral CS on pain & stiffness & functional improvement at 4-6 weeks. https://t.co/u30bPuQOOr https://t.co/4Z1ZpiOcvX

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Dr. John Cush RheumNow ( View Tweet)
EMA in Europe has approved Rinvoq (upadacitinib 45 mg and 15 mg and 30 mg) for the treatment of adult patients with moderately to severely active ulcerative colitis who are DMARD-IR or biologic-IR. Based on 3 phase III trials. https://t.co/BjvUm0wPNk https://t.co/IVisAgD1wZ

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Dr. John Cush RheumNow ( View Tweet)
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