Genetic blood tests indicated that Bruton's tyrosine kinase (BTK) and a cytokine called APRIL were overexpressed in patients with primary Sjögren's syndrome who subsequently developed lymphoma, French researchers reported, suggesting that BTK inhibitors might be useful in this population.
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Dr. Christina Chambers, an epidemiologist at the University of California San Diego and the principal investigator of MotherToBaby Pregnancy Studies, reviewed the available data on psoriatic arthritis and pregnancy. There is little evidence at this time that pregnancy affects PsA, though studies reliably demonstrate increase in disease activity in the post-partum period in both skin and joint disease.
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A UK population-based study suggests that autoimmune diseases affect approximately one in ten individuals.
ICYMI: Psoriatic Arthritis and Pregnancy
Christina Chambers, PhD, MPH delivered a standout lecture on psoriatic arthritis and pregnancy on Saturday, the first day of RheumNow Live 2023.
Check out the summary from Dr Eric Dein ( @ericdeinmd )
https://t.co/Lo8FpewC4V https://t.co/ntp47kwKbK
One in Ten has Autoimmune Disease
A UK population-based study suggests that autoimmune diseases affect approximately one in ten individuals.
https://t.co/WpsnDGiNHt https://t.co/llGcOFQMmx
Watch: Insights into the Future of Osteoarthritis
RheumNow Live 2023: Philip Conaghan, MBBS, PhD, University of Leeds, Biomedical Research Centre
https://t.co/xjccnULOBn https://t.co/inIDFDN7GA
RNL23 Replays (5.6.2023)
This week on the podcast we feature replay content from RNL 2023, cannabis effects on pain and sleep, and what drives PJP risk the most - steroids or RTX?
https://t.co/hmJQBq3krb https://t.co/xeh0gOqoTf
Downs Syndrome (1/700) & autoimmune mechanisms - Downs has a 4-6 fold higher risk of JIA, type 1 diabetes, autoimmune thyroid disease and coeliac disease. https://t.co/wVUDRCS96I https://t.co/RosPAkRnPA
Thanks to these Rheumatology Influencers who were tweeting & teaching from RheumNow Live 2023!
Look for all the RNL23 Replays this month- videos, podcasts, articles, & tweets
@ericdeinmd @doctorRBC @NoufAhmedAlham2 @Janetbirdope @uptoTate @anisha_dua @DrLauraCoates https://t.co/AgvQ06dp3Z
in 2022 COVID slid from the #3 to the #4 cause of death in USA, accounting for nearly a quarter million deaths, a 47 percent decrease from the 462,193 Covid-related deaths in 2021. Most COVID deaths occured in the first few mos of 2022 https://t.co/qervCp0P87 https://t.co/WN7DvsFhNC
Does King Charles have Sausage Digits (dactylitis) or OA? https://t.co/mRis21OWKH https://t.co/mRis21OWKH https://t.co/TmPDKu6ARh
Prevalence and Mortality of IgG4-related disease in the USA
A review of the epidemiology of IgG4-RD in the USA shows a low prevalence with possibly increasing numbers, owing to increasing awareness of this unique immune-mediated condition.
https://t.co/umWCPX4ing https://t.co/ZIButYrtp0
Romosuzumab and Low Sclerostin Levels Underlie CV Risk
New research highlights potential safety concerns around women taking romosozumab, a new anti-osteoporosis drug available on the NHS.
https://t.co/tRGOXrm0Fk https://t.co/ebiRpCC81p
Contratulations to Dr Germain Honvo (Univ. of Abomey-Calavi, Univ. Liège/Belgium) in receiving the 2023 Pierre Meunier Young Scientist Award from ESCEO & the International Osteoporosis Foundation (IOF) for his work in osteoarthritis, aging & locomotion https://t.co/gOB6VfP9vn https://t.co/SBbexkty4F
Clinical overview of subacromial pain syndr (SAPS) Brit J Sports Med. SAPS has heterogeneous causes; Dx by physical examination and imaging. Need to exclude glenohumeral OA, frozen shoulder, GH instability, rotator cuff tears, neuro & cervical disorders https://t.co/d77kXa2qSi https://t.co/vBF0692huh
DDW 2023 study claims microscopic colitis (MC) pts had a 2fold higher risk of #RA. 11,293 MC pts matched 1:5 w/ population controls. With 8 yrs of F/U, RA was found in 1.1% of MC vs 0.6% controls (adj HR 1.92 (95% CI = 1.56-2.34). https://t.co/R5faYDoaAq https://t.co/qiaOMgOyLR
REMIT-UC: Tofacitinib study 334 w/ Ulcerative Colitis:Clinical remission in 35%, Endoscopic remission in ~24%; & low risk (per/100PY) of serious infections (2.1), H zoster (0.5), & VTE (1.1). Loss of response in 45%, but recaptured 55% w/ dose escalation https://t.co/OgQYcq9pQk https://t.co/1KtLDvkQGT
BMJ Systematic review of OP trials (69 RCTs, >80k pts) & Fx rates in postmenopausal F shows protective effect of bisphosphonates, PTH receptor agonists, & romosozumab vs PBO. Most effective PTHra > ROMO > Denosumab > bisphosphonates > PBO https://t.co/wKVCUnjmNT MJ
715 women w/ infertility from recurrent implantation failure were randomized to either placebo or prednisone 10 mg/d. Live birth rates were unaffected by pred (37.8% 38.8% w/ PBO; NS), but pred did increase rate of preterm deliveries (11.8% vs 5.5%; P=.04) https://t.co/ey5JDk2Xi5 https://t.co/Rcgphj147r
Treatment and Management of Neuropsychiatric Lupus
On the first day of ACR State of the Art conference in Orlando, Florida, Dr. Michelle Petri reviewed the treatment and management of neuropsychiatric lupus.
https://t.co/99GXxyIjLl https://t.co/Bor7R2qVtN


