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This week on the podcast we feature replay content from RNL 2023, cannabis effects on pain and sleep, and what drives PJP risk the most - steroids or RTX?
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A current review of the epidemiology of IgG4-related disease (IgG4-RD) in the USA shows a low prevalence with possibly increasing numbers, owing to increasing awareness of this unique immune-mediated condition.
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New research highlights potential safety concerns around women taking romosozumab, a new anti-osteoporosis drug available on the NHS.
Dr. John Cush
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Stop RA trail:
Plaquenil didn’t prevent RA in patient with pre clinical RA. Kevin Deane #RNL2023 @RheumNow https://t.co/gO9QKbAues https://t.co/gEpuBvDpj5
Dr. John Cush
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#RNL2023 @RheumNow
There are a lot of RA Rx on market now - do we need more?
Dr. Brenner: YES
Stromal targets like LIF/LIFR, Notch3, cadherin-11 offer upstream benefits for our difficult to treat RA patients that don't respond to tradition cs/bDMARDs https://t.co/Og1vvbTRO9 https://t.co/WyqPH0lgkd
Dr. John Cush
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JAKinib safety takeaways
- avoid in older population 65 yo, malignancy, CV risk, VTE risk
- appropriate in younger pts without VTE/CVD risk factors
#RNL2023 @RheumNow https://t.co/mFvvqJ9Jbp https://t.co/A76tR2S1Rb
Dr. John Cush
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#RNL2023 @RheumNow
Dr. Stanley Cohen: possible adverse effects of JAKi
-Herpes zoster, other infections
-Malignancy
-Occasional cytopenias
-LFTs (with DMARDs)
-Incr Cr or CPK
-Acne
-Incr lipids
-GI perf
-VTE
Which do you counsel with your patients? https://t.co/zncCw3jlK7 https://t.co/AHhDyxaumM
Dr. John Cush
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Dr. Stanley Cohen on JAKinibs:
Very concise and informative timeline on the multiple JAKinibs approved for multiple conditions
@RheumNow #RNL2023 https://t.co/ulLh2HikUt https://t.co/0kR8CNZvsV
Dr. John Cush
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How do you prevent RA in at-risk patient?
Smoking cessation! Healthy weight and exercise! Diet! Periodontal health! 🚭🏋️🥕🦷
Education follow-up!
Not robustly proven to prevent/delay RA, but may be more important than early DMARD intervention! Kevin Deane, MD
#RNL2023
Dr. John Cush
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STOP-RA study on HCQ preventing RA...
HCQ did NOT prevent RA development in pre-RA pts
@RheumNow #RNL2023 https://t.co/uZRqAxWyyo https://t.co/02qUN4Hhrc
Dr. John Cush
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Heart to Heart: Cardiovascular Risk in RA
Tune in to hear experts discuss cardiovascular risk assessment, patient education, and the importance of disease control in the latest therapeutic update sponsored by AbbVie US Medical Affairs.
https://t.co/qfnayksf3q https://t.co/7D62APLK4Z
Dr. John Cush
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Full Read comprehensive revie by Isenberg on what Rx work in SLE; they review RCT data on approved drugs and Rx in development:
- Obinutuzumab
- Dapirolizumab
- Deucravacitinib
- Litifilimab
- Atacicept
- Telitacicept https://t.co/WZQ3soseDB https://t.co/UdkmFYhbGv
Dr. John Cush
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COMING UP NEXT! Join us May 9th for our next Tuesday Night Rheumatology. We'll be focusing on Modern Management of Psoriatic Arthritis
Remission in Psoriatic Arthritis
JAK inhibitors in Psoriasis and PsA
Pregnancy in PsA
https://t.co/8HZZAO1qIX https://t.co/UPGYXqGGu6
Dr. John Cush
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New download available!
RA Flares: Management and Risks
https://t.co/Ct1FXEueE2 https://t.co/7dsrJvu7hK
Dr. John Cush
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Tuesday Night Rheumatology: Rheumatoid Arthritis: Revolutionary Advances in Therapy
Check out this week's Tuesday Night Rheumatalogy focusing on RA.
https://t.co/oNu4XCY0ez https://t.co/Gll5Uraqwy
Dr. John Cush
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Watch: Year of the JAKi
https://t.co/NaZn8w1YYY https://t.co/GzhQpz8ZfM
Dr. John Cush
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Lupus During Pregnancy Carries Higher Maternal, Fetal Morbidity Risks
Women with SLE had higher risks for maternal and fetal morbidity compared to those without the chronic autoimmune disorder, according to a nationwide analysis of U.S. data.
https://t.co/iD4pGZPzQm https://t.co/zl9lX7i8es
Dr. John Cush
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Pericarditis Management
Dr. Cremer, a cardiologist at the Cleveland Clinic Foundation, reviewed the questions patients ask about pericarditis including why the disease develops, will it recur, how is it treated, and what will their treatment duration be.
https://t.co/EiK3YDzXvT https://t.co/MrS9WeYn0r
Dr. John Cush
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Treatment and Management of Neuropsychiatric Lupus
On the first day of ACR State of the Art conference in Orlando, Florida, Dr. Michelle Petri reviewed the treatment and management of neuropsychiatric lupus.
https://t.co/csmOHMm8oZ https://t.co/EiWI2e7PF7
Dr. John Cush
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ACR 2023 Convergence Brings Back the Poster Hall and 4 Day Meeting
ACR Convergence 2023, the annual meeting of the ACR and the world’s premier rheumatology experience, will be held Nov. 10 – 15 at the San Diego Convention Center in San Diego, CA.
https://t.co/2yFL5m5Y4f https://t.co/rzTbvRv3nT
