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RA,hand,elderly,active

Malnutrition and Quality of Life in Elderly RA Patients

d Jack Cush, MD

Rheumatoid arthritis (RA) imparts a significant disabilty and quality of life (QoL) limitations worsened by aging, but also by malnutrition.

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exhaustion,depression

Lupus Frailty Index Predicts Organ Damage

d MedPage Today

Patients with longstanding systemic lupus erythematosus (SLE) who were considered frail were more likely to accrue disease damage over time, a secondary analysis of data from a Chicago lupus cohort found.

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knee2_0.JPG (keep)

AAOS Clinical Practice Guideline for Knee Osteoarthritis

d Jack Cush, MD

The American Academy of Orthopaedic Surgeons has published their Clinical Practice Guideline for Management of Osteoarthritis of the Knee (Non-Arthroplasty); updating 19 of the 29 evidence-based recommendations and focuses on nonsurgical treatmentss to provide pain and patient function.

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Study of 380 nonintubated severe COVID-19 pneumonia patients showed that those with the highest tertiles of FERRITIN (1322-13 ,418) showed significant reduction in mortality (HR, 0.16; 0.06-0.45) if given methylprednisolone [120-240] mg https://t.co/Jr1aWlPpOk

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Secukinumab (IL-17 inhibitors) can be safely used in HIV spondyloarthritis patients. https://t.co/hpCRJkR9w7

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EHR record study: prevalence of Psoriatic arthritis (#PsA) was increased w/ psoriasis severity. PsA prevalence=2.9 per 100 PY; Based on severity - Mild 2.1/100PY; Moderate 9.9/100PY & severe PSO: PsA risk was 17.6/100PY https://t.co/hXeA773KN4 https://t.co/AUIYZiSq5k

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Novel study of Pain Reprocessing Therapy;PRT in Chronic Back Pain. 151 pts w/ 10 yrs of LBP: 4 wk results - better w/ PRT (66%) (were pain-or nearly pain-free) vs PBO (20%) vs Usual care (10%), with gains maintained through 1-year follow-up https://t.co/lioI99GP80

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NEJM Clinical Images: Sweets syndrome (Acute Febrile Neutrophilic Dermatosis) - 46F w/ raised painful lesions on extremities. https://t.co/up5PviNDeS)

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ICYMI: New data from the CDC shows that obesity rates have risen in the USA during the pandemic, with 16 states having obesity rates of 35% or higher - that's four more than last year, adding Delaware, Iowa, Ohio and Texas to the list. https://t.co/9nFuea2BOV https://t.co/XmsXmFXhzv

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POETYK PSO-1 and PSO-2 trial results seen at the EADV meeting, studying Tyk2 inhibitor, deucravacitinib vs PBO or apremilast in 666 & 1020 plaque psoriasis pts. Wk 16 PASI 75 higher in DEUC ((59%, 54%) vs Otezla (35%, 40%) vs PBO(13%,9%) https://t.co/qok68Kbb6J

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ASBMR meeting presented results of the ASTEROID trial in osteogenesis imperfecta; Setrusumab, investigational Mab inhibitor of sclerostin, failed to improve radial trabecular BMD (primary endpt), but did improve lumbar/hip/femoral BMD https://t.co/xSDIiffjb7

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RA patients had a higher 30-day rehospitalization than OA after TKR (OR 1.11) and THR (OR, 1.39). While infections, postoperative complications, cardiac did not differ, RA TKR had less VTE, but RA THR had higher VTE risk (OR, 2.41) https://t.co/QlOWngcEnJ

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Stills disease and SpA? 8 pts (5 AOSD, 3 systemic JIA) who met Stills and ASAS criteria, 7/8 developed SpA a meant of 6.2 yrs after Stills Dz. SpA types included 2 peripheral, 3 axial SpA, 4 PsA & 1 SAPHO. Amongst Stills pts 7-10% developed SpA https://t.co/RfeUxE7N7S

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ICYMI: Download today! “Jack of All Subspecialties”—find wherever you get your podcasts. https://t.co/UvQRiLOWsr #RheumNow https://t.co/IiFSBhWCcH

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New data from the CDC shows that obesity rates have risen in the USA during the pandemic, with 16 states having obesity rates of 35% or higher - that's four more than last year, adding Delaware, Iowa, Ohio and Texas to the list. https://t.co/9nFuea2BOV https://t.co/ZjloYnG5oQ

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ICYMI: Can I get the INFLUENZA and COVID Vaccines together? The CDC says: "YES...both vaccines can be given at the same visit, people should follow the recommended schedule for either vaccine.... ideally get a flu vaccine by the end of October." https://t.co/T49zm6kWGE https://t.co/WQMx3XhHmL

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What will happen after COVID - more panic and neglect of public health? An interesting read from The Atlantic. “Progress is always undone; promise, always unfulfilled. “ Is America Prepared for the Pandemic After COVID-19? https://t.co/AA9qIo0DMH

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ICYMI: JAK inhibitors as potential treatment for Juvenile Dermatomyositis: nice review of the biology of JAKi effects and the reports of JAKi success in adults and kids with IIM https://t.co/k3qunsCdBN https://t.co/nyqMo6vh88

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ICYMI: U.S. Preventive Services Task Force (USPSTF) reaffirmed its recommendations that pregnant women at a high risk of preeclampsia should take a daily aspirin regimen at the end of the first trimester https://t.co/DiV7p5YxEd https://t.co/FJu7BxEkkw

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In case you missed it— A longitudinal study from Iceland shows an increasing number of native joint infections (NJI), with iatrogenic, postarthroscopic infections being of particular concern. Read more… https://t.co/n82PpZ7a96 #RheumNow https://t.co/SmOBX0701N

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