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myositis, polymyositis, wikipedia

Skin Involvement with HMGCR Necrotizing Myositis

d Jack Cush, MD

The Journal of Autoimmunity reports that anti-HMRCR antibody positive, necrotizing myositis patients frequently have cutaneous lesions, moreso than previously reported.

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covid vaccine

Rheumatic Flares Uncommon After COVID Vax

d MedPage Today

Post-vaccination disease flares were uncommon among patients with rheumatic and musculoskeletal diseases who were inoculated against COVID-19, researchers found.

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morbidity,covid,heart,lung,brain

Multimorbidity Impairs Responses in Rheumatoid Arthritis

d Jack Cush, MD

A retrospective analysis of the ACR RISE registry shows that multimorbidity is not only common in patients with active rheumatoid arthritis (RA), but also impacts treatment choices and outcomes.

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Mumps,Parotid

CRESS – A New Composite Measure for Primary Sjögren's Syndrome

d Jack Cush, MD

Randomized clinical trials in primary Sjögren's syndrome (pSS) are fraught with fault and inconclusive outcome measures, including the more recently developed EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI).  There's a new composite endpoint outcome for RCTs in pSS, called the Composite of Relevant Endpoints for Sjögren's Syndrome (CRESS).

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Serum adipokine CTRP9 levels may predict severe lung dz in Systemic Sclerosis (SSc-ILD): Retrospective longitudinal Registry/Biorepository study; 110 SSc pts - 31% had elevated CTRP9 assoc w/ lower FVC. Low CTRP9 assoc w/ FVC Stability. https://t.co/AY4U12kwPr

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54-year-old man with several weeks of diffuse abdominal pain/tenderness. Feet and hands showed diffuse petechia. CT scan - occult ileocecal perforation and segmented small bowel wall thickening in Intestinal skip lesions. Most likely diagnosis?https://t.co/DaeiC1gqln

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A retrospective analysis of the ACR RISE registry shows that multimorbidity is not only common in patients with active rheumatoid arthritis (RA), but also impacts treatment choices and outcomes. https://t.co/72Lcqxjoly

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Dr. John Cush RheumNow ( View Tweet)

Retrospective study of 80 kids w/ systemic JIA - 12 pts changed anakinra to cananinumab & continued w/ clinical inactive Dz (CID). 68 active sJIA Rx w/ CAN: 57% CID off GCs at 6 mos & 64% at 12 mos. NonResponse predicted by #active jts ≥5, hx of MAS https://t.co/QkmqzRrjp6

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Dr. John Cush RheumNow ( View Tweet)

CRESS – A New Composite Measure for Primary Sjögren's Syndrome https://t.co/7tvjBvP3g4

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Dr. John Cush RheumNow ( View Tweet)

A prospective, longitudinal study of the cognitive development of children born to mothers with rheumatoid arthritis (RA) demonstrates normal development as measured by comparative school test scores. https://t.co/6Dfdnin1aI

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Cohort study of 66 874 postmenopausal women older than 50 years finds fracture to predict a greater risk of subsequent fracture (regardless whether 1st fracture was traumatic or nontraumatic). All such pts need OP assessments https://t.co/EQtDdZb8Vz

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Systematic review of Kawasaki Dz treatment (4 RCTs, 456 pts) shows MAb & anti-cytokine biologic use does not reduce Coronary artery abnormalities (RR 0.93; [95%CI], 0.65 to 1.32) vs IVIG, but Abs did reduce Rx resistence (RR 0.60) https://t.co/FJkQfxCkjB

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Congrats to Deborah Veis, MD, PhD, appointed to be the next editor-in-chief of Journal of Bone & Mineral Research Plus (JBMR Plus). Dr Veis is a professor in the Division of Bone & Mineral Diseases at Washington University School of Medicine https://t.co/9aOibSdhqC

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JRheum review: 40–50% of psoriasis pts have psoriatic nail disease NP). NP is an important predictor of enthesitis, which is associated with the early stages of PsA https://t.co/sEuih3CSgX

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ICYMI: FDA Approves IVIG in Dermatomyositis https://t.co/PoHtzDYekk The FDA has approved Octagam 10% [Immune Globulin Intravenous (Human)], as the first and only intravenous immunoglobulin (IVIg) formulation to be approved for adult dermatomyositis (DM). https://t.co/eAQa2oPOOf

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Dr. John Cush RheumNow ( View Tweet)
Hands-Down Rheumatology - Sarcoidosis usually presents as a monarthritis or oligoarthritis. Late sarcoid arthritis affects knees, ankles, fingers (dactylitis). Bony lesions show honeycomb trabecular pattern). https://t.co/85zvhk4Poz https://t.co/pb9ABL5O8a

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ICYMI: Potential Birth Defects with Hydroxychloroquine HCQ is one of the safest meds used in rheumatology, but there is new claims data suggesting a small increase in the risk of malformations associated with first-trimester HCQ use. https://t.co/k1LOQvWlVm https://t.co/Ka96e733rp

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Dr. John Cush RheumNow ( View Tweet)
A prospective, longitudinal study of the cognitive development of children born to mothers with rheumatoid arthritis (RA) demonstrates normal development as measured by comparative school test scores. https://t.co/6Dfdnin1aI https://t.co/rJFn9WuCgO

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Dr. John Cush RheumNow ( View Tweet)
AstraZeneca announced today that anifrolumab (Saphnelo or anifrolumab-fnia) was approved by the FDA for that treatment of adult patients with moderate to severe systemic lupus erythematosus (SLE) who are receiving standard therapy. https://t.co/22HVA32IAh https://t.co/xZNfepcDLQ

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Don't forget to register for the ACR Virtual Townhall Wednesday 8/4/21: 7 PM ET Re: COVID vaccination effectiveness for rheum patients w/real world data @ACRheum @alhkim @rheum_cat https://t.co/CKAwSLMv8R

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k dao KDAO2011 ( View Tweet)

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