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RheumNow Podcast – Systemic Sclerosis Pearls (2.19.2021)

d Jack Cush, MD

Dr. Jack Cush reviews nearly a dozen news and journal reports from the past 2 weeks on RheumNow.com, including the ACR's new COVID-19 vaccine guidance for patients with rheumatic disease.

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High Risk Cancer Profiling with Inflammatory Myositis

d Jack Cush, MD

A recent metanalysis of studies suggest you may be able to use certain clinical factors to stratify cancer risk in patients with idiopathic inflammatory myopathies (IIMs).

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Avacopan - Is it Really a Win for ANCA-Associated Vasculitis?

d Jack Cush, MD

The NEJM has reported the results of a study showing that avacopan, a C5a receptor inhibitor, is as effective as steroids at treating patients with antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV).

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Alveolar Hemorrhage and Mortality in Lupus

d Jack Cush, MD

Metanalysis of patients with diffuse alveolar hemorrhage (DAH), show this to be a rare and life-threatening complication of systemic lupus erythematosus (SLE), that is more apt to affect older, severe lupus patients with active infection.

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Checkpoint Inhibitor Use with Pre-existing Autoimmune Disease

d Jack Cush, MD

Annals of Internal Medicine reports treating advanced melanoma with immune checkpoint inhibitors (ICI) in patients with pre-existing autoimmune disease (AID) was as effective and safe in those with AID compared to those without AID, although severe colitis occurred more frequently among pati

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RheumNow Podcast is now up! Systemic Sclerosis Pearls Dr. Jack Cush reviews nearly a dozen news and journal reports from the past 2 weeks on https://t.co/fxtCOkxTER, https://t.co/nKRmKWR0Bd https://t.co/ESdycxLoCz

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High Risk Cancer Profiling with Inflammatory Myositis A recent metanalysis of studies suggest you may be able to use certain clinical factors to stratify cancer risk in patients with idiopathic inflammatory myopathies (IIMs). https://t.co/TjmdGtdDQG https://t.co/tlfVU031fY

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Dr. John Cush RheumNow ( View Tweet)
QD Clinics - Traveling to Medical Meetings during COVID Is it Safe to Travel? https://t.co/flELrZbjnw https://t.co/ixebtW71fx

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Dr. John Cush RheumNow ( View Tweet)
Avacopan - Is it Really a Win for ANCA-Associated Vasculitis? The NEJM has reported the results of a study showing that avacopan, a C5a receptor inhibitor, is as effective as steroids at treating patients with ANCA-AAV. https://t.co/vWmhEhX8Z3 https://t.co/omXpouPKoJ

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Dr. John Cush RheumNow ( View Tweet)
SF analysis usually confirms dx, but changes dx 14%. 264 SF samples showed MSU crystals in 89% gout, 9% of CPPD pts. CPP crystals found in 54% of CPPD, 43% of OA & 7% of gout pts. Ca hydroxyapatite seen 1/3 RA, 1/2 OA & 2/3 CPPD https://t.co/B8UkHagXK3 https://t.co/UTncLo6Fyu

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Dr. John Cush RheumNow ( View Tweet)
Alveolar Hemorrhage and Mortality in Lupus Metanalysis of patients with DA), show this to be a rare and life-threatening complication of SLE, that is more apt to affect older, severe lupus patients with active infection. https://t.co/EILQZTYYjk https://t.co/kDAFuYIJuH

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Dr. John Cush RheumNow ( View Tweet)
Email Survey study of HSS rheumatic pts 7,094 responded 1,547 were women (18-50yrs) & 61 (4%) were pregnant during COVID. COVID prevalence was similar in PREG vs nonPREG (8% vs.9% ), PREG COVID pts had shorter Sxs, more loss taste/smell. https://t.co/4HDuXbZVrs

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Dr. John Cush RheumNow ( View Tweet)

2021 RWCS Review podcast is now available- #RWCS Available on SoundCloud and Apple/Android https://t.co/eLk3vqoAT8 https://t.co/U8YjToQlIS

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Dr. John Cush RheumNow ( View Tweet)
QD Clinic - RA and DVT Counseling Patients on JAKs and Thrombotic Risk https://t.co/efQGtkrxHF https://t.co/mfhjZYMlUC

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Dr. John Cush RheumNow ( View Tweet)
Checkpoint Inhibitor Use with Pre-existing Autoimmune Disease https://t.co/S9SQVAKJ8q https://t.co/FOjp2Pk61a

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Dr. John Cush RheumNow ( View Tweet)
Very high levels of IL-18 IL-18 (> 10 000 pg/ml) is associated with Macrophage Activation syndrome (with systemic JIA) as well as primary and secondary Hemophagocytic lymphohistiocytosis (HLH) https://t.co/dotoaYbuPd

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Dr. John Cush RheumNow ( View Tweet)

On March 24, 2021 the FDA Arthritis Advisory Committee and Drug Safety .... Committees will meet online to will discuss biologics license application, for tanezumab, from Pfizer, for the proposed treatment of moderate to severe osteoarthritis in adults https://t.co/NSlutqdHzu

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Congratulations again to @Tuhina_Neogi, the newly installed Alan S. Cohen Professor of Rheumatology https://t.co/rxWhMOg7w0 https://t.co/vcErMRrvom

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BU/BMC Rheumatology BU_BMC_Rheum ( View Tweet)
Not sure how Lenny wins $50 chanting "Autoantigenomics" - read on anyway... https://t.co/rbghM0PPOl

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Dr. John Cush RheumNow ( View Tweet)

Italian IBD clinic with 90 IBD Vedolizumab Tx pts, 8%(11) developed severe enthesitis (4 Multifocal, 6 unifocal). Sxs after mean 46 wks, CRP=5.1 mg/dl, majority HLA-B27 negative; confirmed by PD/UA in 7 - 4/7 developed post-inflam entheseal calcifications https://t.co/uwAJM8giBX

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Dr. John Cush RheumNow ( View Tweet)

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