Gout | More than Flares
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Pragmatism in Gout: How therapeutic choices can have multiple benefits

Michael Toprover, MD

William James famously wrote in Pragmatism, “There can be no difference anywhere that doesn’t make a difference elsewhere.” Gout treatment offers a striking medical example of that idea. Drugs prescribed to calm flares or lower uric acid are designed with one primary goal in

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Gout in Minority Populations Recent research has revealed substantial racial and ethnic disparities in both who develops gout and the care patients receive. These differences reflect not only genetic susceptibility but also the substantial influence of social determinants of https://t.co/SKEsQVZPw6
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The Hidden Cost of Gout

Mrinalini Dey, MBBChir, MA(Hons) Cantab., MRCP, FHEA

For many people, gout is viewed as an episodic disease: a painful flare, a short course of treatment, and then life returns to normal. However, as rheumatologists, we know that recurrent attacks can lead to joint damage and tophi if left untreated. Furthermore, the true burden of gout extends

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Gout TRUST trial compared gout flares in 28 pts assessed biweekly electronically or by phone. Over 12 wk (109 flare periods, 108 electronic & 99 phone assessments) there were 23 flares on electronic surveys and 22 flares on phone surveys (96% agreement; strong concordance, ICC https://t.co/fugYIasf4G
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Why Do Gout Flares Start at Night? The striking propensity for gout flares to initiate at night has been recognized for centuries. More recent epidemiological research supports this observation, indicating that the risk of a gout flare is more than twice as high in the early https://t.co/FbCUmXEl2y
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Rheumatoid arthritis is found in 2-3.8% of gout patients. For more gout content, follow our Gout: More than Flares campaign at https://t.co/lQoiFjubZJ, https://t.co/moAOVUJjKZ

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QD Clinic: Allopurinol for All Gout? Not Quite Dr. Brian Jaros, Chicago, discusses the use of allopurinol. https://t.co/XENBDqZ2Z6 https://t.co/KFTZwuYVLI

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QD Clinic: When There's Doubt in Gout Dr. Eric Dein discusses how imaging was used in correctly diagnosing a mid-foot symptom in gout. https://t.co/FNI6rlOz1O https://t.co/Xpw98DiEvs

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Seronegative RA Disease Activity (7.17.2026)

Jack Cush, MD

Dr. Jack Cush reviews the news, journal articles and Gout features from this past week on RheumNow.com.

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Gout Imaging in Care Gout is all about the crystals and the consequences of the disease are due to the inflammation they cause. Getting rid of urate crystals is the ultimate goal in gout, as we now know that it leads to the risk zero of flares and it normalizes the https://t.co/DGuiTOtQFa
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Saliva and Uric Acid Testing A recent report from China reaffirms the potential utility of salivary uric acid (UA) testing delivers smartphone-guided, enzyme-free gout screening at home for pennies per test. https://t.co/VtvJuPNEWA https://t.co/pdBmy5JoQd

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Four Things About Allopurinol Hypersensitivity Syndrome Dr. Robert Terkeltaub discusses allopurinol hypersensitivity syndrome in gout patients. https://t.co/5seiyfVLW1 https://t.co/0A1Rtk9hzS

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The Marriage between Gout and the Kidney

Richard J. Johnson, MD

While the link between uric acid and gout was first described by Alfred Baring Garrod in the 1800s, the proof that uric acid might actually be the cause had to await the self-experimentation of two rheumatologists from the University of Pennsylvania. Given some comments that the presence of

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many heads

Gout in Minority Populations

Hyon K. Choi, MD, DrPH

Gout is the most common inflammatory arthritis, but its burden is not shared equally across populations. Recent research has revealed substantial racial and ethnic disparities in both who develops gout and the care patients receive. These differences reflect not only genetic susceptibility but

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In 2010 Colchicine fell under patent protection and price increased 16 fold, & out-of-pocket price increased 4.4-fold, colchicine use decreased 27%, while allopurinol, steroid & gout visits (ER, Rheum) increased. https://t.co/xyOxsnoM5z https://t.co/yoXehV0mPa

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Premenopausal women can get gout, if they are post-transplant, taking cyclosporin or tacrolimus. For more gout content, follow our Gout: More than Flares campaign at https://t.co/lQoiFjubZJ, https://t.co/kawSlJ2tb6

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Less than 10% of gout patients have crystal-proven gout. For more gout content, follow our Gout: More than Flares campaign at https://t.co/lQoiFjubZJ,

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Gout Cavalcade (7.10.2026) Dr. Jack Cush reviews the news, journal articles and regulatory decisions from the past week. July is Gout: More than Flares month. https://t.co/I1zWdx9fzU https://t.co/EYQ3D9Z42t

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Why Do Gout Flares Start at Night?

Dr. Raewyn Poulsen

The striking propensity for gout flares to initiate at night has been recognised for centuries. In 1683, Thomas Sydenham famously observed that the typical patient "goes to bed and sleeps in good health" only to be awakened around 2:00 AM by excruciating pain. More recent

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While not a validated Dx tool for gout, AI retinal scanning of digital fundus photography was tested on 107730 pts & showed high ROC - f NIDDM 0.833, Gout 0.832, OP 0.787, HTN 0.740, hyperlipidemia 0.736 & thyroid Dz 0.699 https://t.co/1yrlR04z4g https://t.co/c04YtVVERY

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Gout Imaging in Care

Prof. Tristan Pascart

Gout is all about the crystals and the consequences of the disease are due to the inflammation they cause. Getting rid of urate crystals is the ultimate goal in gout, as we now know that it leads to the risk zero of flares and it normalizes the cardiovascular risk level of patients

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"People wish their enemies dead—but I do not; I say give them the gout, give them the stone!" — Mary Wortley Montagu

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Uric Acid: Is Lower Better? There is good evidence that a serum urate less than 6 mg/dL is required to meaningfully reduce urate crystal and gout flare burden, but is even lower better and are there any tradeoffs? https://t.co/W5FsDC5FG0 https://t.co/7mRgkg00uV

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The mortality gap in gout has not improved in 20 years – CV disease is the leading cause of death (2-fold increase). For more gout content, follow our Gout: More than Flares campaign at https://t.co/xnBVBN5IXZ, https://t.co/c12GmMaatt

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QD Clinic: Cellulitis Paradoxes Dr. Richard Conway, Dublin, discusses a case of cellulitis and gout. Presented as part of RheumNow's "Gout: More than Flares" campaign during the month of July 2026. https://t.co/ZeYyISJrrE https://t.co/2Ih4QRa7FK

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Therapeutic Updates

Systemic Burden of Gout

Dr. Mark Fisher
Watch our 'Systemic Burden of Gout' series as part of this month's Gout More than Flares campaign. Videos include: Gout Management in Patients with CKD, Gout and CVD, and Gout & Obesity.
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Podcasts

  • TU: Systemic Burden of Gout Part 2 (24 plus)
  • Gout Lessons from the Clinic Part 3
  • Systemic Burden of Gout Part 1
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