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I have entered more patients with #COVID19 in the @rheum_covid registry in the last 3 days than I have in the last 3 months. Come on Texas- we can do better! Wear your mask, watch your distance, and help each other stay healthy #July4th @RheumNow
k dao @KDAO2011 ( View Tweet )
3 years 9 months ago
Series of 11 severe COVID-19 pts Rx w/ Anakinra. 7/11 recv anakinra w/in 36 hrs - none required ventilation. 4 got anakinra after 4days of Resp Sx & required ventilation; 1 died. Pts were SARS‐CoV‐2+, w/ fever, ferritin >1,000 ng/mL & acute resp failure. https://t.co/vegsJPrSGp
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Dr. John Cush @RheumNow ( View Tweet )
3 years 9 months ago
66 critically ill & 13 non‐critically ill COVID‐19 were tested for multiple anti‐phospholipid (aPL)Abs. APL common (47%) in critically ill, may be transient (35‐39d post onset). Multiple medium/high levels aPLs may identify at risk for CVA or APS
Dr. John Cush @RheumNow ( View Tweet )
3 years 9 months ago
Schulz-Koops reports 2 #RA patients Rx with RTX who died from COVID pneumonia and ARDS. Both were older, had comorbidities (COPD, HTN, OP) and had received last RTX either 2 wks and 6 mos before COVID infection onset; both had nl IgG levels https://t.co/j043Tggdbg
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Dr. John Cush @RheumNow ( View Tweet )
3 years 9 months ago
Increased rate of hospital #COVID-19 cases associated with some but not all chronic #inflammatory or #autoimmune conditions compared with reference population.
The risks seem to depend on age, the specific disease and previous therapies.
https://t.co/8j6R0oO99y https://t.co/n3cEXFx9Kk
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ARD & RMD Open @ARD_BMJ ( View Tweet )
3 years 9 months ago
Now with ~1,000 children and adolescents with multi-inflammatory syndrome in children (MIS-C), it can be considered a new disease. Today new @NEJM reports and an editorial on its status. I've made a summary of some key points to start https://t.co/1HSWSvumpv
Eric Topol @EricTopol ( View Tweet )
3 years 9 months ago
RECOVERY RCT, dexamethasone vs usual care in COVID19
⬇️28d mortality in pts on O2 (21.5% vs 25%, NNT ~22) or IMV (29% vs 41%, NNT~8)... ?⬆️ for pts w/out O2
1. Preprint*️⃣
2. No blinding, but hard outcome & meaningful benefit
Will likely be adopted, kudos 🇬🇧 for a useful RCT! https://t.co/m5OAYMIvZy
Mike Putman @EBRheum ( View Tweet )
3 years 9 months ago
Early COVID 1255 patients In Wuhan, China - median age 64 yrs; 53 male: 63% w/ chronic comorbidities. There were 17 autoimmune pts w/ COVID () - median age 64; 83% female; only 1 admitted to ICU and one died. 10 stopped DMARDS & 5 their Dz worsened https://t.co/1KgU9tYUqV
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Dr. John Cush @RheumNow ( View Tweet )
3 years 9 months ago
The 5 states with the highest slope of case increasing, per million population, June 20th
1. Arizona (way out in front)
2. South Carolina
3. Florida
4. Texas
5. Oklahoma (pre-rally) https://t.co/M1PsBgmhJb
Eric Topol @EricTopol ( View Tweet )
3 years 9 months ago
RheumNow Podcast is Up! New FDA approvals for secuminumab, canakinumab, risk of GI perforations, tocilizumab in COVID, Weaning DMARDs/Biologics and Blacks with AS. Watch here>> https://t.co/2fTQPJ5iSr Listen to the podcast on Soundcloud>> https://t.co/uPklKQEauE
Dr. John Cush @RheumNow ( View Tweet )
3 years 9 months ago
