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COVID 19 Updates from RheumNow

TNR Grand Rounds - Cytokine Storm Syndromes

This week's Tuesday Nite Rheumatology featured Dr Randy Cron from the University of Alabama - Birmingham as he spoke and took questions on the immunology, immunopathogenesis and treatment of Cytokine Storm Syndrome, especially as they relate to COVID-19 and rheumatic disease patients.

Boston and Wuhan Report Rheum COVID Patients at Risk for Respiratory Failure

Two current reports from Boston and Wuhan describe cohorts of COVID-19 (+) rheumatic disease patients who generally do well but appear to have a higher risk of pulmonary involvement.

Hydroxychloroquine Improves Survival in Lupus

Hydroxychloroquine (HCQ) has dominated the news in recent weeks, because of poor outcomes reported when used in COVID patients.

Low Risk of COVID-19 Pneumonia in Rheumatic Patients

A current letter in the Annals of Rheumatic Disease details the rheumatic disease patient cohort outcomes from the University of Siena, Italy showing only 2 cases of COVID-19 among 859 patients treated with tsDMARDs and bDMARDs.

Again, Antimalarial Use Fails to Benefit COVID

Today Lancet reported the results of another retrospective trial showing that hydroxychloroquine or chloroquine, alone or with a macrolide antibioitic, offered no additional benefits to COVID-19 patients, but was associated with higher rates of mortality and arrhythmia.

Outcomes of Critically-Ill COVID Patients in NYC

Lancet has reported COVID outcomes from NewYork-Presbyterian hospitals in NYC during March 2020 showing high rates of hospitalization, ICU admission, mechanical ventilation and death. 

TNR - COVID-Rheumatology Registry & COVID in OZ

This week's Tuesday Nite Rheumatology features presentations and interviews with Drs. Peter Nash and Philip Robinson. Dr. Robinson presents latest data on the Rheum-Covid.org Registry, that he helped establish under the Global Rheumatology Alliance. Dr.

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High Dose Anakinra Effective in COVID-19

Anakinra was studied in 29 COVID(+) patients with respiratory distress and high inflammatory markers (CRP or ferritin) and compared to non-anakinra patients, those on anakinra had better survival (90% vs.

The Nine Lives of Hydroxychloroquine (Updated)

Hydroxychloroquine is one of many medications frequently used in rheumatology practice.

RheumNow Podcast - COVID Kids and Men (5.15.20)

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.

CDC on Pediatric Multi-System Inflammatory Syndrome

The latest hazardous spinoff to the coronavirus infection is an inflammatory, Kawasaki-like syndrome unique to children or adolescents with COVID-19. Sporadic reports from around the globe of this severe pediatric COVID syndrome have littered the news with brief mentions and little detail.

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Case report in Annals Internal Med shows efficacy of tocilizumab in Cytokine Storm Syndrome; 51-yo renal transplant COVID+ pt developed multiorgan failure, cytopenias, CRP 262 mg/L, ferritin 52005 - failed MMF, DEX, tacrolimus- turned around w/ TCZ 8mg/kg https://t.co/MMNQGB9SA7

Dr. John Cush RheumNow( View Tweet)

6 days 3 hours ago
Governor Cuomo cites NY study showing front line workers have lower rates of COVID positivity - Suggests that WEARING PPE's Works! (NY population 20% vs 14% transit workers & 12% healthcare workers & 10.5% NYPD and 17% FDNY/EMTs) https://t.co/pfC9rKHKVz

Dr. John Cush RheumNow( View Tweet)

6 days 23 hours ago
NEJM report shows that hospitalizations for acute MI are down ~-40% with the onset of the COVID Crisis (data from Kaiser N. California) - Will the shutdown/lockdown lead to other necessary services or hospital admissions? https://t.co/onpFhsDE9Z

Dr. John Cush RheumNow( View Tweet)

1 week ago
A patient service Video - How to Manage your Arthritis Medications (in the time of COVID) - View the video here: https://t.co/hWW0h8wCZn or listen to the podcast on iTunes or here>> https://t.co/8wV4V2pYY5 https://t.co/SldbyCBDeI
Dr. John Cush RheumNow( View Tweet)
1 week ago

BCG & COVID: 1) Israeli study shows BCG vaccination during childhood had no protective effect on getting COVID-19 infection later. 2) Bladder cancer pts on BCG therapy who get COVID infection, can safely take IL-6 or IL-1 inhibitors, Just not TNF inhib. https://t.co/TlOj6b8Taf

Dr. John Cush RheumNow( View Tweet)

2 weeks ago
New axioms in the time of #COVID-19 1. Always assume every patient may have COVID-19 2. Always assume your Zoom camera is on. 3. Always assume your microphone is live. 4. Always assume something will be fundamentaly different next week. @medicalaxioms #covid4MDs

T. Scott Diesing, M.D. diesing_t( View Tweet)

2 weeks ago
Tuesday Nite Rheumatology Grand Rounds by Dr. Joan Merrill (OMRF) on "What Does COVID-19 Have to do with LUPUS". Watch it here>>https://t.co/q5Om4CQAnP or listen on iTunes or here>> https://t.co/yJWsmds0cg

Dr. John Cush RheumNow( View Tweet)

2 weeks ago
Interview w/ Private Practice Rheums on Covid - Drs. Herb Baraf and Danny Ricciardi. DC & Brooklyn Docs wrangle technology, Telehealth, Return to normal, the future and more. Watch it here>> https://t.co/TaMbiF9MLC or listen on iTunes or here>> https://t.co/G7sR23bwLW

Dr. John Cush RheumNow( View Tweet)

2 weeks ago
Why are more MEN (severely?) affected in COVID-19? Men have higher levels of circulating ACE2 (unrelated to ACEi or ARB HTN meds) based on a Biobank study of 1485 men, 537 women. ACE2 is found in lungs, heart, kidneys, vessels & testes https://t.co/CWXevTNYWm

Dr. John Cush RheumNow( View Tweet)

2 weeks 2 days ago
A new feature of COVID-19; "Covid toes" manifest as multifocal, asymmetric, erythema, ecchymoses, ischemic changes that blister or appear vasculitic. The toes, heel and soles can be affected. Healing in 12-20 days. https://t.co/Isqn9ebnQj

Dr. John Cush RheumNow( View Tweet)

2 weeks 2 days ago
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