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COVID 19 Updates from RheumNow

Vaccine Efficacy in Patients with Seronegative Spondyloarthritis

Vaccine efficacy remains an important and highly discussed topic at this year’s annual meeting given the ongoing COVID-19 global health crisis, current influenza season, and recently published 2022 ACR guidelines for vaccinations in patients with rheumatic and musculoskeletal diseases.

Does Evusheld shield people living with rheumatic diseases?

Fast forward nearly 3 years since the first case of COVID-19 was reported, and I am amazed of the speed of response on how to keep our patients with rheumatic and musculoskeletal disease (RMD) safe from this infection.

Long COVID and Rheumatic Disease

The COVID-19 pandemic has had a significant impact worldwide particularly among those who are immunocompromised. Numerous studies have highlighted the increased risk of acute SARS-CoV-2 infection among patients with rheumatic diseases (RD).

Creaky Joints Presentations at ACR Convergence 2022

The patient advocacy organization CreakyJoints will present 13 scientific posters at this year's ACR Convergence 2022 and 8 posters as part of the patient perspectives track. Below is a sampling of these scientific posters. 

Women with Rheumatic Disease (11.4.2022)

Dr. Jack Cush reviews the news and journal articles from this past week on RheumNow.com.  New regulatory decisions about JAK inhibitors and why do women with rheumatic diseases have unfair outcomes?

Undiagnosed RA During the Pandemic

EurekAlert!

The number of new diagnoses of rheumatoid arthritis fell by 20% in the first year of the COVID-19 pandemic, new research suggests.

Infections & Lupus (10.28.2022)

Dr. Jack Cush discusses the news and journal reports from the past week on RheumNow. This week more lupus nephritis, more drug induced lupus and more lupus infections that may kill. 

ACR Award Winners (10.21.2022)

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. Highlighted discussion of implantable stimulators, urine proteomics and gut-immune responses to Prevotella in RA.

Vaccination Cut Long COVID Risk for Rheum Patients

MedPage Today

Patients with rheumatologic conditions who developed breakthrough COVID-19 infection after vaccination were less likely to suffer long-term symptoms than unvaccinated but otherwise similar patients, researchers said.

RheumNow Podcast – “That’s Not My Name” (10.7.2022)

Dr. Jack Cush goes off on "Untitling" (not using proper names/titles) in the clinic, in addition to reports on rheumatologist salaries, new drugs in phase 1-3 development and the range of COVID-19 MSK symptoms -- all from the past week on RheumNow.com.

Great and Not So Great (9.30.2022)

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.

COVID-19 Arthropathy and Myalgia

An online survey of random COVID-19 infected persons shows that arthralgia and myalgia are common consequences to COVID-19 infection.

Social

Recent CDC/MMWR report shows Paxlovid x 5days (including those w/ prior COVID or vaccination), had a 51% lower hospitalization rate within 30 days after diagnosis than those not prescribed Paxlovid. Use it irrespective of vaccination status https://t.co/CBc1VBSDFR https://t.co/EC8QGaFrb3
Dr. John Cush @RheumNow ( View Tweet )
3 days 19 hours ago
TIME Mag - "Why Masks Still Matter". 1) COVID is still out there; 2) Influenza on the rise. Authors write "With limited yet mixed data, we would be wise to ...err on the side of masking in high risk, indoor crowded public settings..." https://t.co/l8jiTwAdZz https://t.co/0QUKJDOhjs
Dr. John Cush @RheumNow ( View Tweet )
1 week ago
Does Evusheld shield people living with rheumatic diseases? Dr. Yuz Yusof ( @Yuz6Yusof) discusses three key abstracts from #ACR22 on Evusheld findings.https://t.co/wYl6Wpd5Fs https://t.co/7T7u4czNOX
Dr. John Cush @RheumNow ( View Tweet )
1 week 1 day ago
COVID Highlights Dr. Leonard Calabrese and Dr. Cassandra Calabrese share highlights on COVID data being presented at #ACR22 https://t.co/DEUykGt8pT https://t.co/sz8GRRGrPH
Dr. John Cush @RheumNow ( View Tweet )
1 week 5 days ago
Impact of COVID 19 on Pregnancies in Women with RMD Dr. Cassy Sims ( @DrCassySims) discusses abstract 0950 at #ACR22. https://t.co/qbFRV5P3eP https://t.co/cmS4n15L5e
Dr. John Cush @RheumNow ( View Tweet )
1 week 5 days ago
Vaccination +/- prior Covid-19, and with either mRNA or vectored DNA vaccines were not associated with AIRD flares. Negative association 21-days after 1st Covid-19 vaccination and no association after 2nd or 3rd doses. Nakafero G Abs#2194 https://t.co/vA8cMNQGkr #ACR22 @RheumNow https://t.co/SZnXejnmYt
Dr. Antoni Chan @synovialjoints ( View Tweet )
3 weeks ago
Problem w antibodies to prevent #COVID19 infection in rheumatic Pts is that they are not as good in variants that are more prominent ex Omicron strains. But should we use in high risk Pts ex long rituximab users? I do in this group. @RheumNow #ACR22 https://t.co/A8soYbg9ZD
3 weeks ago
L08 #ACR22 TIX/CIL (Evusheld) in Rheum Pts 157 pts, f/u 154 days 24 breakthrough COVID ifns (15%) 2 pts required hospitalization, rest had mild-mod symptoms No SAEs (CVD) @RheumNow
3 weeks ago
In a prospective cohort where MTX was withheld for 1 week post COVID vaccine, antibodies higher than other DMARDs which were continued (mostly RTX/MMF). Good to see more direct data rather than having to extrapolate from flu. @RheumNow ABST0913 #ACR22https://t.co/YphKywNJfA

Julian Segan @JulianSegan ( View Tweet )

3 weeks ago
Even young SLE patients are still at high risk of severe COVID: - in general pop, age is key factor - in SLE, risk is high across age groups (maybe due to both meds & disease) - vaccination makes a big diff but SLE pts still at high risk ABST1591 @CCalabreseDO #ACR22 @RheumNow https://t.co/ra1F79ITn3
3 weeks ago
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