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COVID 19 Updates from RheumNow

RheumNow Podcast – Do More DMARDs Mean More Switching? (9.17.2021)

Dr. Jack Cush reviews the news and journal reports and takes cases and questions from rheumatologists.

Effect of Diet on COVID Outcomes

A smartphone-based symptom study of COVID-19 patients has shown that a healthy plant-based diet was associated with lower risk and severity of COVID-19, especially amongst those living in areas with higher socioeconomic deprivation.

RheumNow Podcast – High Science and Future Treatments (9.10.2021)

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com

COVID Breakthrough Infections in Rheumatic Patients

Analysis of records from the Mass General Brigham healthcare system in the Boston area, shows that breakthrough infections (after receiving SARS-CoV-2 vaccines) in patients with systemic autoimmune rheumatic diseases (SARDs) are not uncommon, and may be severe or fatal.

Not All Immunosuppression Alters Vaccine Immunogenicity

Chronic inflammatory disease (CID) patients are urged to receive the COVID-19 vaccines; but when a cohort of CID patients treated with immunosuppressive medications were given an mRNA-based SARS-CoV-2 vaccination, only those treated with glucocorticoids and B cell depleting therapies (BCDT) had l

RheumNow Podcast – COVID Marching Amidst the Madness (8.27.2021)

Dr. Jack Cush reviews the news, journal reports and cautions regarding COVID-19

Rare Risks Associated with BNT162b2 mRNA Covid-19 Vaccine

The current NEJM reports that the use of the Pfizer mRNA vaccine (BNT162b2) demonstrated a very low risk for certain serious adverse events, including the risk of myocarditis (1 to 5 events per 100,000 persons). 

ACR Guidance on Timing of 3rd Dose Booster with Immunomodulatory Drugs

ACR Press Release

The American College of Rheumatology has issued an updated version of its COVID-19 Vaccine Clinical Guidance for Patients with Rheumatic and Musculoskeletal Diseases following recent recommendations from the CDC that certain immunocompromised patients receive a third dose of an available mRNA vac

FDA Approves First COVID-19 Vaccine

Today, the U.S. Food and Drug Administration (FDA) approved the first COVID-19 vaccine, manufactured by Pfizer-BioNTech COVID-19 the vaccine, now marketed as Comirnaty (koe-mir’-na-tee), is approved for the prevention of COVID-19 disease in individuals 16 years of age and older.

RheumNow Podcast – Driving in Pain (8.20.2021)

Dr. Jack Cush reviews the news, journal articles and more from this past week on RheumNow.com.

Sustained Effectiveness of mRNA Vaccines Against COVID-19 Hospitalizations

MMWR

The CDC has reported that mRNA vaccine effectiveness against COVID-19–associated hospitalizations was sustained over 24 weeks; but there is evidence of waning protection amongst the immunosuppressed.

HHS, FDA & CDC Joint Recommendation on COVID Booster

FDA

Today, public health and medical experts from the U.S. Department of Health and Human Services (HHS) released the following statement on the Administration’s plan for COVID-19 booster shots for the American people.

Social

Differential Dx of immune-mediated necrotizing myopathies (IMNM) - HMGCR & Signal recognition particle Abs; checkpoint inhibitors, anti-Mi2 dermatomyositis, antisynthetase syndr. antimitochondrial Abs, GVHD, SARS-CoV-2 infection https://t.co/hhizx5gAet

Dr. John Cush @RheumNow ( View Tweet )

1 week 1 day ago
Analysis of records from the Mass General Brigham healthcare system in the Boston area, shows that breakthrough infections (after receiving SARS-CoV-2 vaccines) in patients with SARDs are not uncommon, and may be severe or fatal. https://t.co/Ri5QipR7YY https://t.co/TaTFTKfAzm
Dr. John Cush @RheumNow ( View Tweet )
1 week 2 days ago
Confused by all the different types of #COVID 19 tests? They are broken down in an easy-to-use tool here: https://t.co/P5jHhnzFej #Antigen #Antibody #PCR @CreakyJoints @IFAiArthritis @US_Pain @IAFaccess @colorofcci @patientaccess @aimedalliance @patientsrising @AARDATweets

Lupus Association @LADAOrg ( View Tweet )

1 week 2 days ago
3 of 4 COVID hospitalized in NJ are unvaccinated. - 5.6 mill fully Vax; 2.7 mill unvaccinated, - COVID hosp. rate of 4.33/100,000 fully vaccinated & 26.33/100,000 for unvaccinated. - Unvaccinated are nearly 6 times more likely to be COVID hospitalized https://t.co/nvDNODBlRW https://t.co/h3CcLXGLXG
Dr. John Cush @RheumNow ( View Tweet )
1 week 2 days ago
Telephone survey of 278 Rheumatic Pts during COVID (July 2020) showed 22% reduced/interrupted treatments, only 11 (4%) stopped. Decisions made by half (49%). Stop Reasons: anxiety (48%), IV Rx access (45%), Rx unavailability (6.5%) https://t.co/XgJ1TJsHJG

Dr. John Cush @RheumNow ( View Tweet )

1 week 2 days ago
What's your prediction when the Pandemic will end and we can travel, vacation, hug & handshake?

Dr. John Cush @RheumNow ( View Tweet )

1 week 3 days ago
JAMA: In women with spontaneous abortions, COVID-19 vaccine exposure was not increased compared with women without Spont Ab (ongoing pregnancy). COVID-19 vax given to 8.0% ongoing pregnancy vs 8.6% spont ab (adj OR 1.02) https://t.co/wEeaMR98Mf

Dr. John Cush @RheumNow ( View Tweet )

1 week 3 days ago
MMWR: COVID-19–hospitalization rates in kids & adolescents rose 5-fold late June–mid-Aug 2021 (w/ rise of Delta variant). Hospitalization rates were 10 times higher among unvaccinated than fully vaccinated adolescents. https://t.co/Qt5lj3Ycxb

Dr. John Cush @RheumNow ( View Tweet )

1 week 4 days ago
In case you missed it— Booster Shots for Rheumatology Patients on Immunosuppressive Medications https://t.co/dIzrv3B12u https://t.co/nGIUNcqNTf
Dr. John Cush @RheumNow ( View Tweet )
1 week 5 days ago
Our latest @MassGenBrigham rheumatology COVID collaboration with @zach_wallace_md #preprint to share quickly. 16 confirmed breakthrough infections in rheumatic patients since vaccine EUAs in US. 15 symptomatic, 6 hospitalized, 2 deaths https://t.co/atixfBcEbn

Jeffrey Sparks MD MMSc @jeffsparks ( View Tweet )

1 week 5 days ago
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