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RheumNow Week in Review – I Wanna New Drug (9.28.18)

Dr. Jack Cush reviews the news from the past week on RheumNow.com, including news on inappropriate opioids, pre-clinical RA treatment, DMARDs in Gout, the decline of arthroscopy and a pain in the mouth.

ACR Releases State-by-State Rheumatic Disease Report Card

The American College of Rheumatology (ACR) today released the Rheumatic Disease Report Card: Raising the Grade on Rheumatology Care in America, a first-of-its-kind report that evaluates just how difficult it can be to live well with a rheumatic disease in the United States.

New BSR Guidelines on Biologic Safe Use with Inflammatory Arthritis

The British Society of Rheumatology has produced a set of NICE accredited guidelines for the use of biologic therapies in patients with inflammatory arthritis.

The Safety of Paternal Exposure to DMARDs and Biologics

Pregnancy and drug safety is a complex issue, often with limited informatoin about maternal drug exposure on the offspring. Greater uncertainty exists when considering whether paternal exposure may also influence fetal outcomes.

2018-2019 ACIP Recommendations for Seasonal Influenza Vaccination

The current issue of the CDC's MMWR reviews the new seasonal recommendations for vaccination against influenza. This is an update to the previous recommendations of the Advisory Committee on Immunization Practices (ACIP). 

ACR Meets With HHS Secretary Azar to Discuss Step Therapy Concerns

Yesterday, the American College of Rheumatology (ACR) met with U.S.

Maternal RA Increases Offspring Risk of Autoimmune Disorders

A Danish population study suggests that fetal exposure to maternal rheumatoid arthritis (RA) results in an increased offspring risk of thyroid disease, epilepsy and RA, compared to children born to mothers without RA.

IL-1 Suppression May Improve Dilated Cardiomyopathy

 

Interleukin-1 (IL-1) suppression helped reverse symptoms of dilated cardiomyopathy (DCM) for one patient in a case study that may implicate inflammation in the development of the condition.

The RheumNow Week in Review – Lupus in the News (7.27.18)

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.

The RheumNow Week in Review – Cocoon Therapy? (7.20.18)

Dr. Jack Cush reviews highlights from the news and social media on RheumNow.com in the past week. 

The RheumNow Week in Review –Fateful Outcomes in Rheumatology (7.13.18)

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.  Fateful outcomes in Rheumatology, what happens to Seronegatives, IL-23 fails, MRI progression, Not all inflammatory back pain becomes SpA:

Hydroxychloroquine Being Over-Dosed with New Guidelines?

Hydroxychloroquine (HCQ) retinopathy prevention guidelines have revised from ideal body weight (IBW)-based dosing to actual body weight (ABW)-based dosing; the question remains whether these have been adopted in clinical practice.

Social

Smartphone T2T management of RA & SLE is possible. With over 127,316 DAS28 & 42,593 SLEDAI assessments over 2 yrs. T2T was lowest in spring for both, correlating w/ holidays in China. #ACR20 Abstr#1018 https://t.co/bGJtSTDqzo https://t.co/34za6kokOp
Dr. John Cush @RheumNow ( View Tweet )
4 years 10 months ago
Dr Richard Furie-> Obinutuzumab for proliferative #lupus nephritis -Compared to rituximab, has more B-cell depletion in tissue and #SLE patients -Meaningful benefits over SOC alone on renal response through week 104. -Phase 3 REGENCY pending. #ACR20 #ACRambassador #Rheumatology https://t.co/aPi1yueAiV
Mohammad A. Ursani MD, RhMSUS @DrMAUrsani ( View Tweet )
4 years 10 months ago
@andreafava representing @jhrheumatology @HopkinsBayview at plenary session! Urine proteomic biomarkers can revolutionize the way we see LN, and decrease need for renal Bx #Acr20 @RheumNow Abst#0936 https://t.co/zGoqmBPddT
Eric Dein @ejdein1 ( View Tweet )
4 years 10 months ago
Can we use urine testing ( and all the cells, proteins, complements, DNA, rna) to predict LN response? Plenary II @SalemAlmaani @BradRovin @RheumNow #ACR20 @OSUWexMed

alexa meara @lexmeara ( View Tweet )

4 years 10 months ago
Dr. Aggarwal Abs#0955 showed efficacy of IVIG in tx of Dermatomyositis. How/when do you use IVIG for tx of DM? @RheumNow #ACR20

Robert B Chao, MD @doctorRBC ( View Tweet )

4 years 10 months ago
ProDERM study:10% IVIG is effective and safe in pts with DM. First large PBO-controlled, randomized ph 3 trial. @RheumNow #ACR20 abs0995 #ACRbest https://t.co/aJyASaAMlJ
4 years 10 months ago
#HCQ assoc. w/ ↓platelet activity & ↑vascular health in #SLE: - 132 patients, 108 on HCQ - Ex-vivo expts show ↓platelet aggregation & downregulation of platelet functional pathways - HCQ may improve vascular health in SLE Abs#0870 #ACR20 @RheumNow https://t.co/ST9n2HGyhM

Mrinalini Dey @DrMiniDey ( View Tweet )

4 years 10 months ago
HCQ Not Associated with QTc Length in SLE and RA Patients: Dr. Janet Pope @Janetbirdope #ACR20 https://t.co/zPIaFIiqr5 https://t.co/Wk8YQpIpo7
Dr. John Cush @RheumNow ( View Tweet )
4 years 10 months ago
Dr. C Mohan @UTSWNews #ACR20 @rheumnow reviews IFN in SLE: 👉Diff't IFN assc w/diff't lupus manifestions 👉⬆️stim endosomal DNA/RNA sensors RLR7,8,9 may drive SLE 👉TLR7 & 9 in B cells impt for germinal ctrs & Ab prod’n 👉TLR7 is X-linked 👉IFNsig not track w/dz activity https://t.co/3KK3UvH8Ka
4 years 10 months ago
#hydroxychloroquine is not a ‘cutie’ drug. E Park et al showed that HCQ does not increase QT interval in RA & SLE patients including if on other meds that may affect QT but known heart disease excluded from study #ACR20 #ACR2020 @RheumNow abstr#432 @CRASCRRheum https://t.co/FGVPknmj5q
4 years 10 months ago
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