RheumNow Podcast – Steroids, IVIG & the Vaccine (1.15.2021) Save

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. How to handle COVID19 Vaccine issues, IL-6 inhibition in COVID, Comorbidites in RA, IVIG in dermatomyositis, & more...

1. Real good historic review of RA drug development wherein Dr Paul Emery interviews Dr. Mike Weinblatt - Good Listen from the Cytokine Signaling Forum podcast https://bit.ly/3qmWjFd
2. Long Term Safety and Efficacy of Tacrolimus in Lupus Nephritis—Takeuchi et al has published their extensive experience with long-term tacrolimus use in lupus nephritis patients showing its real-world safety and efficacy.  https://t.co/Xdxg3v3wMm
3. 2 yr Early RA cohort (CareRA) study found that RA patients with co-morbidities had over time lower chances of achieving remission (OR = 0.724; 95% CI: 0.604, 0.867) and a higher risk of hospitalization (OR = 3.725; 95% CI: 2.136, 6.494).https://t.co/B1um1iMSKu
4. Telemedicine study on accuracy of Pt reported swelling predicting inflamm arthritis. 1637 pts w/ 13 wks of Sxs. 76% pts reported swelling, but only found by 41% of Rheums. Pt reporting sensitivity was was 87%, but specificity only 31%; PPV=46%, NPV=77% https://t.co/oV3p06BHRj
5. National Psoriasis Foundation Task Force updated their COVID-19 guidance statements. Including Guidance 4.6, stating PsA pts who receive a mRNA-COVID vaccine should continue their biologic or oral therapies as they manage their psoriatic disease https://t.co/byujtDET33
6. After your 2 doses of COVID vaccine, YES you need to continue to wear a mask, cont. hand washing & social distancing - so as to continue to protect yourself and others. While vaccinated you can still become infected and spread infection.https://t.co/TkcSNx0hF1
7. A patient infected with COVID-19- Yes they should get vaccinated ~90days after infection has resolved.Antibody testing is not needed before you are vaccinated. Evidence suggests that reinfection is uncommon in the 90 days after initial infection. https://t.co/TkcSNx0hF1
8. QD Clinic - What to do After COVID Vaccination https://rheumnow.com/video/qd-clinic-what-do-after-covid-vaccination
9. Preprint results of the REMAP-CAP trial in the UK shows that IL-6 inhibitors, when given within 24 hrs of ICU entry for COVID-19, lowers mortality rate by 36%. Hosp mortality in 353 TCZ was 28%, 48 sarilumab was 22% in 402 controls was 36%.https://t.co/fkjOz99t0l
10. Adipose Transplants as a New Regulator of Osteoarthritis
11. Corticosteroid Use Hikes CV Risks in Rheumatic Patients
12. ProDERM Study: IVIG in Dermatomyositis
13. 2020 Rheumatology Year in Review