Ustekinumab: A Novel Intervention in Giant Cell Arteritis
Treatment of refractory giant cell arteritis (GCA) with ustekinumab (Stelara) showed therapeutic promise as a steroid-sparing agent in a small, open-label study, Irish researchers reported.
News
High anti-TNF Failure Rates with Obesity
A meta-analysis has suggested that obesity is an under-reported predictor of inferior response to tumor necrosis factor blockade (anti-TNF) in a range of inflammatory immune-mediated inflammatory diseases (IMIDs), with the results showing a 60% risk of impaired response to anti-TNF across several
Increased Risk of Depression and Anxiety in Rheumatoid Arthritis
Canadian researchers have analyzed population data and shown that the incidence and prevalence of depression, anxiety and bipolar disorders are elevated in the rheumatoid arthritis (RA) patients compared to a matched population.
ACP Policy Calls for Increased Efforts in Women's Health Issues
The American College of Physicians have published a position paper in Annals of Internal Medicine calling for an examination of the challenges facing women in the U.S.
Cancer Risk Raised in Psoriatic Arthritis
Patients with psoriatic arthritis (PsA) were at increased risks for malignancy, and possibly more so if they were treated with conventional disease-modifying antirheumatic drugs (DMARDs), a meta-analysis found.
In nine cohort studies that included more than 43,000 PsA patients, the pooled relative risk for overall malignancy was 1.29 (95% CI 1.04-1.60) compared with the general population, according to Yunyun Fei, MD, and colleagues from Peking Union Medical College in Beijing.
Restless Sleep and Inactivity Intertwined in OA
Adults with osteoarthritis (OA) of the knee who frequently experienced restless sleep were less likely to engage in potentially beneficial moderate-to-vigorous physical activity, analysis of data from the Osteoarthritis Initiative found.
The RheumNow Week in Review – Methotrexate CIRT Study (5.25.18)
Dr. Jack Cush reviews this past week's news from RheumNow.com - the risk of Cutaneous and Systemic LE, increasing flu vaccination, higher risk of VTE, MPO predictions, new drug for GIOP and CIRT - MTX in cardiovascular risk patients.
Measures of Opioid Misuse Predict Future Opioid Overdose and Death
The current issue of Annals of Internal Medicine examines patterns of potential opioid misuse that are associated with subsequent adverse outcomes nationally.
MPO Antibodies Predict Relapses in MPO-ANCA-Associated Vasculitis
A study of MPO-ANCA positive patients followed serially over 2 years shows that reappearance of MPO‐ANCA may predict relapse in patients with MPO‐ANCA positive AAV and that routine MPO‐ANCA monitoring is warranted.
FDA Approves Denosumab for Glucocorticoid-Induced Osteoporosis
Amgen announced that the U.S.
ACR Leaders Lobby Capitol Hill for Help on Rising Costs and Access Barriers in Arthritis Care
Rheumatologists and rheumatology health professionals convened on Capitol Hill this week to urge legislative action on pressing policy issues affecting rheumatology care during the American College of Rheumatology’s Advocacy Leadership Conference, held May 16 -17, 2018 in Washington, D.C.
Autoinflammatory Syndromes Show Dramatic Response to Canakinumab
The New England Journal of Medicine reports that the anti-interleukin (IL)-1β monoclonal antibody canakinumab (Ilaris) was effective in the treatment of three distinct autoinflammatory recurrent fever syndromes (FMF, TRAPS, HIDS) with responses that were far superior to what was see
