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C5orf30 Gene is a Negative Regulator of Tissue Damage in Rheumatoid Arthritis

PNAS has reported the work of an international team of scientists from the University College Dublin and the University of Sheffield, who have studied DNA samples and biopsy samples from joints of over 1,000 rheumatoid arthritis patients in the UK and Ireland and determined the C5orf30 gene to be

DSB: Drug Shortages August 2015

RheumNow is committed to reporting safety issues in our monthly Drug Safety Bulletins. Each month we will update you with reports of new, ongoing and resolved Drug Shortages that will affect the practicing rheumatologist.

Increased Vascular Mortality in Ankylosing Spondylitis

Haroon et al has analyzed administrative claims data from Ontario, Canada and compared 21473 AS patients with 86606 normal comparators matched for age, sex, and location of residence.

Growth Hormone Protects Against Osteoporotic Fractures

This article was sourced from sciencedaily.com

In a decade-long study of the effects of growth hormone (GH), 80 women with osteoporosis on HRT, between ages of 50-70 yrs were randomized to receive GH 1.0 U or GH 2.5 U recombinant human GH or placebo sc daily during 3 years and compared to an age-matched populatoin sample of (n=120).

Hyperuricemia, Death & Kidney Disease

In a recent study published in the Journal of the American Geriatrics SocietyTaiwan investigators examined the Annual Geriatric Health Examination Program database (2006 to 2010) to estimate the all-cause, cardiovascular, and cancer mortality risks associated with serum uric acid le

Female "Viagra Pill" Controversy - Grandstanding or Equal Rights?

The FDA is under pressure over the recent approval of the "female viagra" pill.  On August 18th, the FDA announced its approval for Addyi (flibanserin) to treat acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women.

Early RA and the Chance of DMARD-Free Remission

Early and aggressive treatment of rheumatoid arthritis has become the mantra for most who manage the disease and hope to achieve optimal outcomes - including remission.

BMI at Age 20 Influences Future Risk of Low Back Pain

A nationwide, cross-sectional study of men aged 30–50 years (n=1385) examined the relationship between weight and back pain over time.

Fasenmyer Grant to Calabrese and Lederman Will Further the Interface Between Rheumatology and Virology

Two longtime collaborators studying HIV/AIDS at the Cleveland Clinic and Case Western Reserve University have received an $18.5 million grant from the Richard J. Fasenmyer Foundation.

Epidural Steroid Injections Ineffective

A meta-analysis of 30 placebo-controlled trials evaluated epidural corticosteroid injections for radiculopathy, and 8 trials were done for spinal stenosis.

Colon Cancer Risk Cut by Aspirin and NSAIDs

A population-based study from Northern Denmark studied the effects of aspirin and NSAIDs on colorectal cancer rates (Citation source http://buff.ly/1KJQ6H3).

Secukinumab Bests Ustekinumab in Psoriasis CLEAR Study

The CLEAR study was a one-year, randomized, double-blind trial compared subcutaneous standard doses of secukinumab (anti-IL17) and ustekinumab (anti-IL12/23) in patients with moderate-severe plaque psoriasis.  

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