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A Closer Look at Psoriatic Arthritis Outcome Measures and Disease Control

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A Closer Look at Psoriatic Arthritis Outcome Measures and Disease ControlSlide 2 - Measures of Disease Activity in PsA

Dr. Alexis Ogdie

“...because of the heterogeneous nature of psoriatic arthritis, measuring disease activity is a challenge – there is no single instrument that reflects activity across all disease manifestations.” – Dr. Alexis Ogdie

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Dr. Philip Mease

“There are generally two approaches when measuring disease activity in psoriatic arthritis – a unidimensional approach and a multidimensional approach.”
– Dr. Philip Mease

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Slide 3- Disease Domains Affected in Patients With PsASlide 4 - unidimensional and multidimensional composite measures

Dr. Alexis Ogdie

“The DAS28 or CDAI equivalent in PsA is the DAPSA, an arthritis-focused disease activity measure.” – Dr. Alexis Ogdie

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Dr. Philip Mease

“Data from clinical trials indicate that PASDAS is better at distinguishing treatment effect than DAPSA or DAS28.” – Dr. Philip Mease

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Dr. Alexis Ogdie

"In my clinical practice, we commonly use both cDAPSA and MDA, since cDAPSA can be calculated from a subset of the MDA elements.”
– Dr. Alexis Ogdie

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Dr. Philip Mease

“When setting treatment targets for my patients with PsA, I typically evaluate the items that constitute the MDA and VLDA criteria and strive for VLDA if possible.” – Dr. Philip Mease

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Approval Date: 09/2020 v1.0