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Imaging

Intracellular vs extracellular Calcium Pyrophosphate Crystals in 134 pts - 108 w/ intracellular & 26 w/ extracellular CPP crystals. Having Acute/chronic CPP crystal arthritis - 97% had intracellular and 62 extracellular crystals (p<0.001). Arthritis more likely to be asso w/… https://t.co/oRVNKptLfx https://t.co/06oGP4EyVJ
Dr. John Cush @RheumNow( View Tweet )
Artificial Intelligence in Diagnosing Sacroiliac Inflammation in axSpA A so-called deep learning artificial intelligence (AI) algorithm for analyzing MRI scans showed "acceptable" agreement with expert human readers for detecting sacroiliac joint (SIJ) inflammation in patients… https://t.co/nKbYF603ut https://t.co/Y5IzVIG2l3
Dr. John Cush @RheumNow( View Tweet )
Intracellular vs extracellular Calcium Pyrophosphate Crystals in 134 pts - 108 w/ intracellular & 26 w/ extracellular CPP crystals. Having Acute/chronic CPP crystal arthritis - 97% had intracellular and 62 extracellular crystals (p<0.001). Arthritis more likely to be asso w/… https://t.co/LY32oLJQv3 https://t.co/jSm4dkBICF
Dr. John Cush @RheumNow( View Tweet )

Artificial Intelligence in Diagnosing Sacroiliac Inflammation in axSpA

MedPage Today

A so-called deep learning artificial intelligence (AI) algorithm for analyzing MRI scans showed "acceptable" agreement with expert human readers for detecting sacroiliac joint (SIJ) inflammation in patients with axial spondyloarthritis (axSpA), researchers said.

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Medscapes Diagnostic evaluation of inflammatory myositis patients Labs Imaging EMG/NCV Muscle Bx https://t.co/jDNlqypoq8 https://t.co/dBgMgex4Cw
Dr. John Cush @RheumNow( View Tweet )
Korean population study shows RA was linked to a higher migraine risk, regardless of seropositivity. Comparison of 42,644 RA vs 213,370 controls - found higher risk of migraine (adj HR 1.21; 1.17–1.26). https://t.co/8jlJ4oV95Z https://t.co/r7hsQpt3u7
Dr. John Cush @RheumNow( View Tweet )
ASAS Imaging Recommendations for Suspected Spondyloarthritis ASAS (Assessment of Spondyloarthritis International Society) has convened specialized task force to guide imaging request on patients with suspected/known axial spondyloarthritis (axSpA). https://t.co/snSKDtToHh https://t.co/wpGSHkTwCD
Dr. John Cush @RheumNow( View Tweet )
Hand-Held Imaging Could Transform Arthritis Care A new hand-held scanner developed by UCL researchers can generate highly detailed 3D photoacoustic images in just seconds, paving the way for their use in a clinical setting for the first time and offering the potential for… https://t.co/YSCfoWCXpr https://t.co/du6cruFfRQ
Dr. John Cush @RheumNow( View Tweet )

Stop Counting Bugs (10.4.2024)

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.This week’s rants include the microbiome, PsA treatment choices and fishing for P-values in research.

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Using MRI to Evaluate Knee Pain Interim results from a randomized trial show that middle-aged patients with knee pain and suspected meniscal tears can benefit from MRI scans even in relatively simple cases. https://t.co/xAVA07LcqD https://t.co/YRrZgiMQjs
Dr. John Cush @RheumNow( View Tweet )

Hand-Held Imaging Could Transform Arthritis Care

EurekAlert!

A new hand-held scanner developed by UCL researchers can generate highly detailed 3D photoacoustic images in just seconds, paving the way for their use in a clinical setting for the first time and offering the potential for earlier disease diagnosis.

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Using MRI to Evaluate Knee Pain

MedPage Today

Interim results from a randomized trial show that middle-aged patients with knee pain and suspected meniscal tears can benefit from MRI scans even in relatively simple cases.

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ASAS Imaging Recommendations for Suspected Spondyloarthritis

ASAS (Assessment of Spondyloarthritis International Society) has convened specialized task force to guide imaging request on patients with suspected/known axial spondyloarthritis (axSpA).

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Stratified Cancer Screening in Dermatomyositis

The International Myositis Assessment and Clinical Studies Group (IMACS) have published  evidence and consensus based cancer screening guidelines for patients with idiopathic inflammatory myopathies, including dermatomyositis. 

They proposed 18 final recommendations - 13 were

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Analysis of 5 Nordic registries & 29,478 RA & 10,919 PsA pts initiating 1st bDMARD,s (& 362,087 pop controls). Incident ILD was higher in RA (HR 9.7) & PsA (4.4). but MTX co-use (vs non-use) did not incr ILD in RA (HR 0.9; 0.7, 1.2) or PsA (HR 1.0) https://t.co/xY8COh85Bw https://t.co/weJGirfhDX
Dr. John Cush @RheumNow( View Tweet )

TREAT EARLIER - Methotrexate in Clinically Suspect Arthralgia Patients

Lancet Rheumatology has published the results of the TREAT EARLIER trial, showing the prevention of rheumatoid arthritis may be enhanced by risk stratification, particularly in anti-citrullinated protein antibody (ACPA)-negative people with clinically suspect arthralgia.

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Systemic Sclerosis Insights (9.13.2024) https://t.co/fRbKdSAqxG https://t.co/PMbYDXPHMd
Dr. John Cush @RheumNow( View Tweet )

Systemic Sclerosis Insights (9.13.2024)

Dr. Jack Cush reviews the news and journal articles from this past week on RheumNow.com.

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UK Biobank study of 34209 pts w/ Abdominal MRIs found a dose response assoc. between visceral & subcutaneous fat and chronic MSK pain, moreso in women. Is adiposity causal or casual in the pathogenesis of chronic pain? https://t.co/w4ziJf7FQD https://t.co/SyUfCPOnHX
Dr. John Cush @RheumNow( View Tweet )
CA-125 & PET/CT screening in 1432 myositis. 125 pts had CA-125 w/in 5yrs of onset - 3.1% false-positives (fibroids, endometriosis) & 14.3% false-negatives. 139 had PET done- 5.5% false-positives (LN, lung nodules), 28.6% false-negatives (missed melanoma, breast or prostate CA)… https://t.co/16KSDmp9Kz https://t.co/6QFl4jhDxp
Dr. John Cush @RheumNow( View Tweet )

Conservative Treatment of Acute Vertebral Fractures

A network meta-analysis of pain outcomes in patients with acute osteoporotic vertebral compression fractures (VCFs) showed short-term success with calcitonin and NSAIDs in decreasing pain during activity, but long-term benefits were superior for teriparatide compared to bisphosphonates.

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Linger on the Fingers (9.6.2024)

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. This week with a focus on fingers and better prescriptive follow through.

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IV Methylprednisolone in Giant Cell Arteritis

A retrospective study in giant cell arteritis (GCA) patients suggests there is no added value using higher dose, intravenous methylprednisolone (IVMP) in early GCA.

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Among spondyloarthritis patients with clinical enthesitis, 68% had no ‘active enthesitis’ on ultrasound. Conversely, of those without signs of clinical enthesitis, 15% showed subclinical enthesitis on ultrasound ↓ https://t.co/aVEvOmcEHK
ACR_Journals @ACR_Journals( View Tweet )
IgG4-related disease Nearly any organ can be affected ▶️Salivary glands ▶️Lacrimal glands ▶️Orbit ▶️Pancreatobiliary system ▶️Lung ▶️Kidney ▶️Retroperitoneum 👉🏽https://t.co/758F5iuYwT via @RheumJnl https://t.co/ipONrygHmc
Dr Ai Lyn Tan @DrAiLynTan( View Tweet )