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Imaging

Can Targeting RANKL in RA Heal Erosions?

MedPage Today
Apr 07, 2021

Treatment with denosumab (Prolia) helped heal bone erosions over 2 years among patients with rheumatoid arthritis whose disease activity was well controlled, researchers reported.

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Aortic Calcification and Lumbar Fracture Risk in Older Men

Mar 30, 2021

Fractures of the spine and abdominal aortic calcification (AAC) can both be visualized with spinal imaging; a new report shows that finding both radiographic vertebral fracture and AAC on the same lateral spine images may predict the risk of future incident major osteoporotic fracture in

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Rituximab vs. JAK inhibitors in Rheumatoid Lung Disease

Mar 19, 2021

There are no current FDA approved therapies for rheumatoid arthritis associated interstitial lung disease (RA-ILD) or bronchiectasis, but a recent retrospective cohort study showed equivalent outcomes when RA-ILD patients were treated with either rituximab or janus kinase inhibitors.

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Potent Topical Corticosteroids and the Risk of Osteoporotic Fractures

Mar 17, 2021

JAMA Dermatology has published a Danish national cohort study showing that potent topical corticosteroid use was associated with an increased risk of osteoporosis and major osteoporotic fractures with a dose-response association for cumulative use.



Clearly systemic and inhaled

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Diagnosis & Treatment of Osteoarthritis Reviewed

Feb 22, 2021

Katz, Arant and Loeser have published a comprehensive open-read overview of osteoarthritis (OA) of the hip and knee in JAMA; underscoring the impact, advances, disappointments and guidelines put forth. 



OA affects an estimated more than 240 million people worldwide, and more

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Lung Preservation with Tocilizumab in Early Systemic Sclerosis

Feb 21, 2021

Arthritis & Rheumatology has published the results of a subanalysis from tocilizumab (TCZ) clinical trials showing that Il-6 inhibition was associated with preservation of lung function patients with early systemic sclerosis (SSc).

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Prospective study of 162 early RA pts looked at Xrays (baseline & 5 yrs). RF & ESR predicted erosion & JSN progression; CCP predicted erosions; Smoking & high DAS28 > 5.1 predicted progression of erosions. Obesity negatively predicted JSN progression https://t.co/fue121hHVw

Dr. John Cush @RheumNow( View Tweet )

Feb 15, 2021

NSAIDs in Osteoarthritis: Study Suggests Need for New Look

Feb 08, 2021

Knee osteoarthritis (OA) patients using nonsteroidal anti-inflammatory drugs (NSAIDs) showed greater loss of medial minimum joint space width than did others taking other drugs, registry data indicated.



Compared with current non-users of NSAIDs, those who were treated with these

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Several studies have shown that Xray progression has lessened in recent yrs - presumeably from more aggressive Rx by Rheums! Still - Predictors of Xray long term damage = high ESR/CRP, baseline xray damage, -CCP/RF positivity https://t.co/2iaMiaquEV https://t.co/cgEP4QBvL4

Dr. John Cush @RheumNow( View Tweet )

Jan 29, 2021

Delays in Diagnosis of Axial Spondyloarthritis

Jan 12, 2021

The diagnosis of axial spondyloarthritis (and anklylosing spondylitis) (axSpA) is often delayed and usually not diagnosed by rheumatologists; a recent metanalysis shows that longer delays were attributable to lower education levels, younger age at onset and absence of extra-articular

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Spinal Benefits Seen With Cosentyx in PsA

MedPage Today
Jan 05, 2021

Secukinumab (Cosentyx) was effective for axial manifestations of psoriatic arthritis in a 52-week multicenter phase III study, investigators reported.



The primary endpoint of a 20% response on the criteria of the Assessment of Spondyloarthritis International Society (ASAS20) at week

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Update on Polymyalgia Rheumatica and Giant Cell Arteritis (Best of 2020)

Dec 31, 2020

JAMA has published a clinical update of recent studies on GCA. While PET/CT scanning are novel means of demonstrating activity, they have not changed the diagnostic approach to GCA or PMR and although there are no new proven treatment strategies for PMR beyond glucocorticoids, the FDA has

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SpA: Etiology to Diagnosis to Treatment - An Abstract Roundup

Nov 25, 2020

Here's a review of ten abstracts and presentations on spondyloarthritis encompassing a wide range of topics from etiology to diagnosis to treatment.  

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#BestACR20Tweets RT @DrPetryna : @RheumNow #ACR20 abs1921 single center baseline & follow-up PET/CT scan study in pts w/ refractory LVV-GCA on TCZ: while 83.33%pts achieved clincial remission only 10% experiences normalization of Total vascular score. https://t.co/M97X8fLfLp

Dr. John Cush @RheumNow( View Tweet )

Nov 22, 2020
#BestACR20Tweets RT @Janetbirdope : Filgo decreased MRI inflammation of many structures early in Rx in SpA which seems novel says w Maksymowych 5M015 @RheumNow #ACR20 @CRASCRRheum #ACRbest https://t.co/5HQiIettjh https://t.co/NwFMkLIhWw
Dr. John Cush @RheumNow( View Tweet )
Nov 21, 2020
XRay Bone Erosions in CCP+ Patients with Dr Eric Dein ( @ejdein1) #ACR20 https://t.co/f6RnoExBgk https://t.co/MJCp3sR1UZ
Dr. John Cush @RheumNow( View Tweet )
Nov 21, 2020

Swollen Joints Associated with Ultrasound Synovitis in PsA 

Nov 18, 2020

Ultrasonography has been added to the rheumatologist’s toolbox in recent years as a sensitive imaging modality in assessment of inflammatory arthritis but its relationship with tender or swollen joints is not quite clear. A large study of early, DMARD naive PsA patients shows that swollen joints

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Our latest article is asking: "Erosions on X-ray: can we delegate this to the computers?" by David Liew ( @drdavidliew) #ACR20 https://t.co/YvKjAWebT9 https://t.co/mUCv8ycep2
Dr. John Cush @RheumNow( View Tweet )
Nov 18, 2020
Read our article titled: Best Imaging Techniques for non ANCA Vasculitis by Dr. Alexa Meara ( @lexmeara) as discussed at #ACR20 https://t.co/CyfC8bdq42 https://t.co/HrMGvqcNC4
Dr. John Cush @RheumNow( View Tweet )
Nov 16, 2020
HCQ Not Associated with QTc Length in SLE and RA Patients: Dr. Janet Pope ( @Janetbirdope) abstract #0431 presented Friday at the #ACR20 virtual meeting. https://t.co/zPIaFIiqr5 https://t.co/prJZXWnTVB
Dr. John Cush @RheumNow( View Tweet )
Nov 15, 2020

Erosions on X-ray: can we delegate this to the computers?

Nov 12, 2020

The prospect of automating hand x-ray scoring reliably has always been an enticing one, and data presented at the American College of Rheumatology (ACR) Convergence 2020 suggest this might be in reach in the near future – opening up the prospect of automatic x-ray scoring in real-word

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Filgo decreased MRI inflammation of many structures early in Rx in SpA which seems novel says w Maksymowych 5M015 @RheumNow #ACR20 @CRASCRRheum #ACRbest https://t.co/LOOOn7Hjvp
Janet Pope @Janetbirdope( View Tweet )
Nov 09, 2020
@rheumnow #ACR20 abs1535 retrospective study of SI MRI reveals 20% pts w/out spondyloarthritis have BME on an MRI, predominantly in the antero-middle quadrant. Erosions were seen in 31% of healthy patients and in 61% of patients with spondyloarthritis

Olga Petryna @DrPetryna( View Tweet )

Nov 09, 2020
COX2 inhibitors associated with inhibition of radiographic spinal progression in AxSpA pts compared to non-selective NSAIDs. ⬇️radiographic spinal progression over 2 yrs ⬇️mSASSS progression @RheumNow #ACR20 Abs#2030 https://t.co/p1CeNBm3ma
Robert B Chao, MD @doctorRBC( View Tweet )
Nov 09, 2020
Worth checking out the #ACR20 image competition. Here's an image of cerebral toxoplasmosis during ADA treatment for RA @RheumNow. https://t.co/APPlumeUtA
Eric Dein @ejdein1( View Tweet )
Nov 09, 2020
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