Mental Health

Would be helpful for us (and pts) to better understand rimmunotherapy agent specific risk on subsequent GCA/PMR AFTRER propensity matching of >7k pt on combo nivolumab/ipilimumab compared to pembrolizumab: - PMR RR 3.8x N/I vs. P - no diff in GCA risk @RheumNow #ACR24 https://t.co/IF4Gh7Cumd

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Brian Jaros, MD @Dr_Brian_MD( View Tweet )
Study on SLE treatments: Compared adverse events of anifrolumab vs. belimumab Similar risks for mortality, sepsis, herpes zoster, dialysis, MACE, PE/VTE, COVID-19, URI, pneumonia, and mental illness #ACR24 @RheumNow abst#1527

Bella Mehta @bella_mehta( View Tweet )

What is the impact of social connections on lupus? Abstract #1503: In an NYC SLE cohort, greater social integration and support correlated with less pain, depression, disability, and frailty, while loneliness was linked to worse outcomes. @RheumNow #ACR24 #SDoH https://t.co/5OCCExee06

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Akhil Sood MD @AkhilSoodMD( View Tweet )
❔Can rheum drugs have beneficial effects on cognition? 💊Possible benefits with MTX and TNFis but certainly an active area of research and more studies needed #ACR24 @RheumNow https://t.co/lCnIRLwNjK

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Mrinalini Dey @DrMiniDey( View Tweet )
Harkins @DrTrishHarkins et al. People with PMR exhibit an accelerated physical aging phenotype at baseline. High rates of frailty (41%), pre-frailty (28%), cognitive impairment (74%!), sarcopenia (23%), osteoporosis (21%) @RheumNow #ACR24 Abstr#0740 https://t.co/4ZT8VtGi1W https://t.co/xBQ5CLlb5A

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Richard Conway @RichardPAConway( View Tweet )
Characteristics of difficult-to-treat AS accdg to a retrospective study by @DaoudAnsaam @mmagrey1 et al ⬆️ BMI + comorbidities: HTN, CKD, depression + EAMs: IBD, Pso, iridocyclitis + HLA-B27 Interesting real world data. @RheumNow #ACR24 abs573 https://t.co/GlE4tFpsSz

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sheila @RHEUMarampa( View Tweet )
Are you pts using cannabis? In Canada - 20% reported using w/in past 2 years Use for pain, sleep, anxiety 78% noted efficacy Compare to another study said 57% stopped due to inefficacy, 28% AEs - very diff result 70% did not tell their doc 16S18 @BharatKumarMD #ACR24 @RheumNow https://t.co/6NAECW5MJK

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Eric Dein @ericdeinmd( View Tweet )
How to take cannabis? Do NOT rec inhaled - makes drug level go up high/fast, benefit for rec use but not for medicinal - bronchitis, ?oral cancer Other risks: psychosis - risk in youth, memory loss (poor studies), dependence, respiratory if inhaled Clauw 16S18 #ACR24 @RheumNow https://t.co/coYNl7VOT3

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Eric Dein @ericdeinmd( View Tweet )
Amazing review @NamrataRheum on the important role the rheumatologist can play to improve the care of our older patients! Don’t forget the 5Ms! 🧠Mind (cog/mood) 💊Medication (PIM) 🏃‍♀️Mobility 👉Multi-complexity 💪🏻Matters most (pt priority) @RheumNow #ACR24 #gerirheum https://t.co/0Iv4TdS8AX

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Patricia Harkins @DrTrishHarkins( View Tweet )
Anxiety and Depression Rising in Rheumatoid Arthritis A Mayo Clinic study shows that over three decades, anxiety and depression have become more common in individuals with rheumatoid arthritis (RA). https://t.co/sWawAgDgyS https://t.co/dVTb7QMFNj

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Dr. John Cush @RheumNow( View Tweet )
deperssion.woman

Anxiety and Depression Rising in Rheumatoid Arthritis

Jack Cush, MD

A Mayo Clinic study shows that over three decades, anxiety and depression have become more common in individuals with rheumatoid arthritis (RA).

Data drawn from the Rochester Epidemiology Project identified incident adult RA (age

Read Article
Economic and Mental Health Burden of Rheumatoid Arthritis A University of Mississippi-led comprehensive study of a disorder that affects 4.27 million Americans nationwide is revealing just how significant its burdens are on patients' financial well-being and quality of life.… https://t.co/UpxHJSG6BL https://t.co/luPp1gjlRA
Dr. John Cush @RheumNow( View Tweet )
Rheumatoid,RA,nodules,damage

Economic and Mental Health Burden of Rheumatoid Arthritis

EurekaAlert!

A University of Mississippi-led comprehensive study of a disorder that affects 4.27 million Americans nationwide is revealing just how significant its burdens are on patients' financial well-being and quality of life. Patients with rheumatoid arthritis pay an average of $3,383 more per year

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Mindfulness in Managing Chronic Pain JAMA reports that outpatient resource mindfulness-based interventions (MBIs) delivered via telehealth are effective in managing chronic pain amongst veterans. https://t.co/ytSb03h0Fd https://t.co/vWKvYW9Udb

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Dr. John Cush @RheumNow( View Tweet )
Fatigue, FM, fibromyalgia

2023 EULAR Recommendations on Management of Fatigue

Jack Cush, MD

A 2023 EULAR task force has made recommendations to the approach and management of fatigue in patients with inflammatory rheumatic and musculoskeletal diseases (I-RMDs).

Fatigue is a frequent symptom in rheumatic patients, yet its origins may vary.

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Danish cross-sectional survey 12 713 Inflam arthritis (RA, PsA, SpA) pts & found lonliness in one-third (RA 32%; 36% in PsA & SpA) and highest in SpA w/ depression (66%). Loneliness was correlated w/ disease activity. https://t.co/Q3IswbIwe6 https://t.co/GNohOkkmEw

Links:

Dr. John Cush @RheumNow( View Tweet )
RheumNow Podcast square

I Can't Treat Ugly (9.20.2024)

Jack Cush, MD

Dr. Jack Cush reviews the news, journal articles and a new FDA approval for EGPA, this week on the Podcast.

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Pain_Scale__Arvin61r58.png

Antidepressants for Pain are Weakly Effective

EurekAlert!

University of Sydney research has found people over 65 are being prescribed antidepressants as pain treatment based on international guidelines that use limited evidence. The study found that in the last 40 years there have been only 15 trials globally focusing on the benefit of antidepressants

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Study of 201 pts w/ chronic pain, prevalence of anxiety was 19%; higher in women (OR 7.94) longer pain (OR:1.3) & severe pain(OR:18.7) https://t.co/LD6pjH25qv https://t.co/mrlEo0UkEw

Links:

Dr. John Cush @RheumNow( View Tweet )
RA & OA: Nearly 40% have Anxiety, Depression or Fibromyalgia Researchers at Rush University analyzed clinic MDHAQ data and found between 36-40% of OA and RA patients screen positive comorbid anxiety (ANX), depression (DEP), or fibromyalgia (FM). https://t.co/ZElo9iPfA6 https://t.co/dcE0fAsp2N

Links:

Dr. John Cush @RheumNow( View Tweet )
RheumNow Podcast square

Location, Location, Location (7.26.2024)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. Location matters; Geo-rheumatology?

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reviews_0.jpg

RA & OA: Nearly 40% have Anxiety, Depression or Fibromyalgia

Jack Cush, MD

Researchers at Rush University analyzed clinic MDHAQ data and found between 36-40% of osteoarthritis and rheumatoid arthritis patients screen positive comorbid anxiety, depression, or fibromyalgia.

Read Article
EULAR24,Roundup

EULAR 2024 Rheumatology Roundup (6.21.2024)

Jack Cush, MD

Drs. Artie Kavanaugh and Jack Cush discuss highlights from the EULAR 2024 meeting in Vienna

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How good are we at picking up depression in RA patients? In this Polish registry: - 1.8% had depression diagnosis - 21% had low mood on HAQ & depression has real correlates with disease activity. Plenty to think about with truly holistic RA care! #EULAR2024 POS1045 @drdavidliew https://t.co/ArfqHCKxhz
Dr. John Cush @RheumNow( View Tweet )
Do we give enough attention to pts mental health? 2 cohort 400+ RA tREACH & DEPAR 500+ PsA RA 20% depression 30% anxiety PsA 19% depression 22% anxiety 2 yrs no remission RA OR 2.5 depression OR 1.7 anxiety PsA OR 6.10 depression OR 4.67 anxiety @RheumNow #EULAR2024 POS0946 https://t.co/ok4HRNJqgY

Links:

Aurelie Najm @AurelieRheumo( View Tweet )

Recent Blogs

Choice Overload (and the Way Out)

Jack Cush, MD
paint,choice,overload,color
I recently overheard a very good practicing rheumatologist complain, “why do I need yet another drug for psoriatic arthritis? I have more treatment choices than I have actual PsA patients who need a new or better drug”. Read Post

Comorbidities in RA: Focus on Difficult-to-Treat Disease

Elena Nikiphorou, MD, PhD
Puzzle pieces
The presence of comorbidities naturally complicates treatment choice, patient adherence to medication and patient outcomes, increasing also the risk of making RA ‘difficult-to-treat’. Read Post

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