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Heavy Metal Rheumatology (9.23.2022)

Sep 23, 2022

Below are this week’s highlights from RheumNow, as discussed by Dr. Jack Cush. Thanks to all of you for your kind comments and great reviews of our weekly podcast. Please let us know how we can improve by emailing me or recording your suggestion using the "Ask Cush Anything" link on our website

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USPSTF Recommends Screening for Anxiety and Depression

Sep 22, 2022

The U.S. Preventive Services Task Force has recommended that general practitioners actively screen and identify anxiety and depression in all adult patients under 65 yrs.



The USPSTF was appointed by the Department of Health and Human Services, and has been working on this guideline

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Insomnia,Sleep,bed,night

Melatonin Use Growing, Inappropriate & Potentially Unsafe

Aug 18, 2022

With nearly one-third of adults, adolescents and children having sleep difficulties, many resort to using melatonin. JAMA reports substantial increases in the use of over-the-counter (OTC) melatonin, in all age groups. But is it effective, safe and warranted?



The National Health

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Hit Parade Review (8.12.2022)

Aug 12, 2022

We've got a lot to discuss this week: psoriasis; fatigue; sleep; sural nerve biopsies; uveitis and SpA; diet and RA; tofacitinib and the ORAL surveillance study; what not to take with mycophenolate - and more. In what order should these items be discussed? This week the run down is based on

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Watch: Major Consequences of Depression In RAhttps://t.co/aVzIHDiRZ4 https://t.co/86RLXJKb64
Dr. John Cush @RheumNow( View Tweet )
Jun 08, 2022
RA & dementia - it's getting more damning RA dementia risk: HR 1.25 from Korean nationwide data: RA n=138,592 this follows @MyasoedovaElena's data RA systemic inflamm leading to dementia (AD, vascular)? Need to understand if any DMARD protective OP0271 #EULAR2022 @RheumNow https://t.co/4V7fOtVlnj
Jun 03, 2022
#EULAR2022 OP0067: Depression is a major risk factor (6X!) for mortality in RA. Study may show some bias in the methods, but critical findings for all rheumatologists to consider @RheumNow https://t.co/leeY9zAx4T
Jun 02, 2022
Watch: EULAR 2022 - Day 1 Faculty Recap Pane Drs. Jack Cush, Eric Dein and Kathryn Dao discuss highlights from day 1 at #EULAR2022 - Guidelines, Lupus, and more.https://t.co/OBLt7dOMa3 https://t.co/lHmEOIFIGa
Dr. John Cush @RheumNow( View Tweet )
Jun 02, 2022
Comorbidity in AS from @rheum_cat , Karmacharya et al. Clustering of comorbidities. Depression and hypertension clusters assoc worse disease activity and function @RheumNow #EULAR2022 OP0154 https://t.co/jGQXayAYs9 https://t.co/SnVDhVYQq5
Richard Conway @RichardPAConway( View Tweet )
Jun 02, 2022
#EULAR2022 OP0134: Active RA increases risk of dementia Olmsted County, MINN studying RA risk factors for dementia: ⭐️886 pts incident RA, mean age 65. 103 develop dementia Risk factors: Age, rheum nodules, large jt swelling, depression/anxiety, HTN, CVD events @Rheumnow https://t.co/bUFkzBovAy
Jun 02, 2022
Dementia in RA associated w/ ⚡️Large joint swelling HR 2 ⚡️Any CVD HR 2.25 ⚡️Anxiety HR 1.86 ⚡️Depression HR 2.63 at any time during disease course in retrospective cohort 800+ pts #EULAR2022 @RheumNow OP0134 @MyasoedovaElena https://t.co/MLweRMEZXE
Aurelie Najm @AurelieRheumo( View Tweet )
Jun 02, 2022
🚨 Depression = major comorbidity! DANBIO register 10000+ patients: ❗️10% prescription antidepressants💊 ❗️Cumulative mortality ⬆️ w/ OR>6 ❗️Particularly in age group <55 #OP0067 #EULAR2022 @RheumNow https://t.co/le8VWBFjPK
Aurelie Najm @AurelieRheumo( View Tweet )
Jun 01, 2022
Screen for depression in RA patients! From the #DANBIO registry of 11,000 pts, they found 6X ⬆️mortality in pts w/#RA and #depression . The mortality curve separates early. #Plenary OP0067 @rheumnow #EULAR2022 https://t.co/qfjyejGVzQ
TheDaoIndex @KDAO2011( View Tweet )
Jun 01, 2022
dementia,brain

Is Gout Protective Against Dementia?

May 25, 2022

People with gout appeared less likely to develop dementia than age- and sex-matched peers, a database study from Korea found.



The analysis of more than 5,000 gout patients and 25,000 controls in Korea's national healthcare system yielded adjusted hazard ratios of 0.79 for overall new-

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Long,covid

Long COVID Manifestations

May 24, 2022

The acute consequences of a SARS-CoV-2 infection may be bothersome or devastating, but the long-term consequences may lead to so-called "long COVID" syndrome.  Long COVID appears to affect up to 20% of those who survive COVID-19 infection. 

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Expansive (full read) review of CBD - legal and regulatory overview, availability, physiologic and pharmacologic effects, safety, & risks, standards, use in specific rheumatic disorders. https://t.co/hefwKTmPLK https://t.co/IZKZMOZ5ij
Dr. John Cush @RheumNow( View Tweet )
May 09, 2022
Depression was studied in 208 #PSA patients - Depression was found in 30%. Depression risk was higher in those with higher disease activity (DAPSA; P=.007) and functional impairment (HAQ-DI; p=-.02) https://t.co/0bZ2xPprTp https://t.co/Gdiic5iKCi
Dr. John Cush @RheumNow( View Tweet )
Apr 08, 2022
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RheumNow Podcast – What You Do For & What You Do To the Patient (4.8.2022)

Apr 08, 2022

Dr. Jack Cush reviews the news and journal articles from the past week and discusses the use of fibroscan in RA, steroid hip injections in OA and famous quotes from a famous cardiologist.




  1. CorEvitas Registry study of173 Axial #PsA pts showed 6 mos of bDMARD/tsDMARD resulted

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PsA All the Way – Unmet Needs

Apr 01, 2022

Throughout the month of April 2022, RheumNow is introducing a new approach to education and information sharing – a campaign devoted to a single disease. Our first campaign is entitled PsA All the Way: RheumNow will escalate awareness on this topic, its unmet needs, clarify advances and discuss

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Do you discuss/screen for depression with your patients when discussing pain and fatigue? #RNL2022 @RheumNow

Dr. Rachel Tate @uptoTate( View Tweet )

Mar 20, 2022
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Hand OA and Heroes in Rheumatology (2.11.2022)

Feb 11, 2022

Interesting reports this week about dementia, who gets hand OA and a great list of women Heroes and Pillars of Rheumatology. Tune in as Dr. Jack Cush reviews the news and journal articles from this past week in RheumNow.com.

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Tofacitinib 1st JAK Inhibitor Approved for Ankylosing Spondylitis The FDA approved tofacitinib (Xeljanz, Xeljanz XR) for treating active ankylosing spondylitis in adults, Pfizer announced.https://t.co/NczbrBXBl7 https://t.co/l93OM86qaX
Dr. John Cush @RheumNow( View Tweet )
Dec 17, 2021
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Indications Awaiting (12.17.21)

Dec 17, 2021

There's good news and bad news in rheumatology fellowship matching for 2022.  There's also new FDA approvals and indications, but a new serious safety warning has arisen from the CDC about the J&J COVID-19 vaccine. 

Dr. Jack Cush reviews the latest news, journal reports, regulatory

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Better assessment and management of multimorbidity

Nov 26, 2021

Appropriate assessment and management of comorbidities and multimorbidity in patients with RA is vital for overall health and well-being of the patient, as well as to encourage treatment adherence, and address social, psychological and quality of life factors. 

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Cognitive Impairment in Patients with Rheumatoid Arthritis

Nov 10, 2021

Evidence suggests that RA patients are at increased risk for cognitive impairment. This is likely mediated by certain factors, including chronic inflammation and accelerated atherosclerosis. In the clinical setting, it is important to identify RA patients at increased risk for cognitive

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