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Articles By Jack Cush, MD

Vexas

ICYMI: VEXAS Syndrome - A Review

Beck et al has published a review of the VEXAS syndrome in The Lancet, focusing on the pathogenesis, spectrum, and treatment strategies.

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Knee,injection

ICYMI: Glucocorticoid Injections in Knee Osteoarthritis

A randomized clinical trial of 60 patients found that glucocorticoid injections into the infrapatellar fat pad (IPFP) did not significantly reduce pain scores in patients with inflammatory knee osteoarthritis (compared to placebo).

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Eosinophil

ICYMI: EGPA Review

A current review of eosinophilic granulomatosis with polyangiitis (EGPA) provides current recommendations on diagnosis and management.

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ICYMI: 2025 Update: EULAR Recommendations on Rheumatoid Arthritis Management

The European Alliance of Associations for Rheumatology (EULAR) has updated their rheumatoid arthritis (RA) management recommendations, notably with fewer recommendations (total of 9, down from 11 in 2022 version), by merging and removing previous recommendations.

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ICYMI: B Cells at the Brink in Sjögren Disease

A recent issue of Arthritis & Rheumatology reviews current understanding of the immunopathogenesis of Sjögren disease (SjD) and how that has influenced the quest for drug development for this most systemic autoimmune disorder.

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Brenda McShan: The Creative Heart of RheumNow

A pivotal member of the RheumNow family, Brenda McShan, will be retiring with honors.

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Generic Tofacitinib (6.26.2026)

Dr. Jack Cush reviews the news and journal articles from RheumNow.com. Updates on tofacitinib, CAR-T therapy and AI.

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Self-Directed Cognitive Behavioral Therapy for Chronic Pain

Is self-directed cognitive behavioral therapy (CBT) when augmented with asynchronous, personalized feedback for chronic pain (CBT-CP) superior to clinician-delivered CBT-CP?

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Blood labs

2-Gene Blood Test for Kawasaki Disease in Febrile Children

JAMA Network Open has publshed that a simple 2-gene blood test may aid the earlier diagnosis of Kawasaki disease in children with febrile illnesses. 

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pregnancy,embryo,fetal

No Fetal Risks with First Trimester NSAID Use

PLoS Medicine has published a population-based retrospective cohort study from the Southern Israeli Pregnancy Registry (siPREG) project showing that 1st trimester exposure to NSAIDs was not associated with major congenital malformatoin (MCM) risk. 

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