Articles By Jack Cush, MD
Posterior Reversible Encephalopathy in Lupus
Posterior reversible encephalopathy syndrome (PRES) is a rare neurological disorder with many associations or causative factors that rarely includes autoimmune disorders and lupus.
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FDA Will Review Opioid Analgesic Use and REMS Programs for Pediatric Pain Patients
Amidst a stringent regulatory environment, and with the rising use and abuse of narcotics and increasing regulation limiting narcotic analgesic use, the FDA approved (August 2015) the use of extended-release oxycodone in children (11 to 16 years old) with severe, "around-the-clock" pain
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BeST Trial and 10-Year Outcomes of Four Treatment Strategies
Markusse and investigators from The Netherlands have reported their 10 year results of treating early rheumatoid arthritis (RA) patients using targeted treatment strategies.
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Osteoporotic Fractures at Higher Risk for Subsequent Fractures
Harvey and coworkers reported the results of subjects followed in the Reykjavik study, demonstrating that a first osteoporotic fracture was followed by an increased risk for a second fracture, both immediately and over time.
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HLA-B*5801 Testing Needed in Asians and Blacks with Gout
Choi and colleagues analyzed US hospitalizations (2009–2013) to assess the frequency and racial distribution of patients hospitalized with Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) related to the use of urate-lowering (ULT) therapy (predominantly allopurinol).
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Does Psoriasis Increase Risk of Abdominal Aneurysm?
Danish researchers studied a cohort of 59,423 mild psoriasis and 11,566 severe psoriasis patients over a 14 year period, and found 240 and 50 cases of abdominal aortic aneurysms (AAA), repectively. (Citation source http://buff.ly/1YxGpDA)
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RheumNow Week in Review - 15 April 2016
Video recap of highlights from this week at RheumNow.com.
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Surgical Management of Spinal Stenosis - To Fuse or Not To Fuse?
Three articles (2 studies, 1 commentary) in this week's issue of NEJM tackle the issue of whether fusion adds anything to long-term outcomes in those undergoing decompression for lumbar spinal fusion.
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Biosimilar Reports - April 2016
Major advances in biosimilars have occurred in the last three months, beginning with the FDA Arthritis Advisory Committee voting 21-3 to approve Celltrion’s Inflectra (CT-P13) and ending with the recent approval of Inflectra (generically referred to as infliximab dyyb).
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Lupus Patients Genomically Stratified to Explain Treatment Responses
Systemic lupus is a clinically heterogeneous disorder, unified by requisite clinical features and exuberant humoral response to unknown triggers. While the diagnosis is easy, the disease course and management can be complicated and challenging.
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