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Articles By Jack Cush, MD

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Dr. K. Frank Austen (1928-2023)

Rheumatology mourns the loss of a historic leader in the field, Dr. K. Frank Austen, who died at his home in Maine on June 23, 2023, at the age of 95.

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Scary Outcomes with Systemic Sclerosis Sine Scleroderma

The hallmark of systemic sclerosis is scleroderma, but less than 10% of SSc patients have sine scleroderma (ssSSc). A EUSTAR database review compared the manifestations and outcomes of ssSSC to limited cutaneous SSc and diffuse cutaneous SSc.

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Predictors of Cardiovascular Events in ANCA-Associated Vasculitis

A large, retrospective, multinational study of patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) shows they may be at risk for cardiovascular events (CVEs).

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FDA Delays Bimekizumab Decision, Again

Editor's Note: please note the error in the original report has been corrected to read: UCB affirms there are no open information requests from the FDA regarding the BLA for bimekizumab or bimekizumab manufacturing.

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Paradoxical Psoriasis in Kids Taking TNF Inhibitors

A multicenter cohort study reported a large cohort of pediatric patients receiving TNF inhibitor therapy complicated by psoriasis, regardless of treatment indication or the specific TNF inhibitor.

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High BMI Increases Arthritis Risk

Obesity carries many risks, now a new study in Arthritis & Rheumatology shows that higher body mass index (BMI) increases the risk for several rheumatic diseases, especially in women for both gout and psoriatic arthropathy. 

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TitAIN Study: Secukinumab Efficacy in Giant Cell Arteritis

A phase 2 trial has demonstrated the efficacy of secukinumab, an anti-interleukin-17A monoclonal antibody, in patients with active giant cell arteritis (GCA).

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What is Colchicine Worth? (6.23.2023)

Dr. Jack Cush reviews the news and reports from the past week on RheumNow.com. This week a new colchicine FDA approval, rising rate of IgG4 related disease and what's the safest biologic?

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FDA Approves Colchicine for CV Prevention

The FDA has approved colchicine (Lodoco) for cardiovascular prevention in adults with established atherosclerotic disease or multiple risk factors, making it the first anti-inflammatory medicine with such an indication.

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A Card-Carrying Optimist

I may be a snarky, opinionated curmudgeon, but I'm an optimist when and where it counts. And I think you should join me.

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