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Articles By Jack Cush, MD

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Want to Go Far, Go Together (4.21.2023)

This week on the podcast Dr. Jack Cush reviews the news, regulatory announcements and novel journal reports including a profile on pseudogout, the safety of immune checkpoint inhibitors in RA patients and the diagnostic importance of neutrophils.

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Sex-Specific Differences in Psoriatic Arthritis

A systematic review of published literature on psoriatic arthritis (PsA), clinical features, disease activity, and patient-reported outcomes (PROs) shows generally higher levels of disease activity in women, compared to men with PsA.

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Immune Checkpoint Inhibitor Safety with Pre-existing Rheumatoid Arthritis

Lancet Rheumatology has published a retrospective analysis showing patients receiving immune checkpoint inhibitors (ICI) for cancer have the same outcomes (mortality and severe immune-related adverse events (irAEs)) even when they have pre-existing rheumatoid arthritis (RA).

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The Match Game (4.14.2023)

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com, including Rheumatology success in the NRMP MATCH, Cocaine vasculitis and worrisome safety risks with Biologics and tsDMARDs.

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Why I Hire Women

Organizational psychologist Adam Grant points to a metanalysis of 63 studies, showing that women who assert their ideas, make direct requests, and advocate for themselves are liked less, AND they are also less likely to get hired. For me, these are exactly the attributes I am hiring - ideas, assertiveness, speaking up, advocating.

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Pain and Opioid Updates

Today, the CDC and FDA provided new updates on the scope of pain in the USA and guidance on the use of opioids. MMWR April 14, 2023

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RA Patients on Biologics and tsDMARDs are still High Risk

A new Swedish ARTIS registry study of key safety outcomes in rheumatoid arthritis (RA) patients receiving either targeted synthetic or biological disease-modifying antirheumatic drugs (b/ts DMARDs, including Janus Kinase inhibitors (JAKi)), has been updated and affirms previously held risks.

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Best Treatments for Immune Checkpoint Inhibitor-associated Arthritis

A retrospective study of cancer patients who developed immune checkpoint inhibitor-associated inflammatory arthritis (ICI-IA) shows that biologic DMARDs were more effective than conventional synthetic DMARDs (csDMARDs) in rapid control of arthritis.

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Clinical Profile of RA-associated Interstitial Lung Disease

A prospective, cross-sectional analysis of patients with rheumatoid arthritis (RA) shows those with interstitial lung disease (ILD) tend to be older, obese and have a smoking history.

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Rheumatologist - Work-Life Survey Results

During the week of April 3, 2023, registered Rheumatologists responded to an email survey regarding work-life balance. The following are the results from 190 respondents - 53% were male (47% female) and 94% were from the USA.

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