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Articles By Jack Cush, MD

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Burden of BMI on Costs of Musculoskeletal Diseases

A cross-sectional global study shows a substantial impact of obesity and BMI on the health and economic impact of patients with musculoskeletal (MSK) disorders.

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PsA Til Death Do Us Part (1.20.2023)

Dr. Jack Cush reviews the highlights from the past week on RheumNow.com.

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AS, but not PsA, has Increased Mortality Risk

Inflammatory disorders are often accompanied by an increased mortality risk, either from secondary malignancy, infection or cardiovascular disease.

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Hydroxychloroquine Dose and Risk for Incident Retinopathy

A cohort study in Annals of Internal Medicine shows that higher hydroxychloroquine doses was associated with progressively greater risk for incident retinopathy.

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Poorer health outcomes for at-risk patients with fractures

People at high risk of fracture who also have complex or multiple chronic medical conditions are less likely to receive treatment for the underlying osteoporosis and also have poorer health outcomes, according to a new study from the Garvan Institute of Medical Research.  

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Elevated Uric Acid Is Associated With New‐Onset Atrial Fibrillation

A Longitudinal Swedish study has shown that elevated serum uric acid (SUA) levels has cardiovascular implications and may predict the development of atrial fibrillation (AFib). 

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Rheum Believe it Or Not (1.13.2023)

Dr. Jack Cush reviews the notable standouts in the news since the 1st of January.  Surprising reports on ferritin, alcohol benefits, cannabis for pain and a lower dementia risk with hydroxychloroquine.  Here are the links below.

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RA Disease Activity and Alcohol Use

Despite its well known toxicities, alcohol is known to be antiinflammatory. The effects of alcohol use in rheumatoid arthritis (RA) is less known, but a recent study suggests that alcohol consumption was dose-dependently associated with lower disease activity and higher health-related quality of life in RA patients.

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Worse Birth Outcomes in RA and SLE

A population-based retrospective cohort study patients with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants demonstrated significant adverse pregnancy outcome, particularly the infants of women with SLE.

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Bimekizumab in Active Psoriatic Arthritis - BE COMPLETE study

BE COMPLETE is published, showing that bimekizumab (BMK), a selective dual inhibitor of interleukin (IL)-17F and IL-17A, results in superior improvement in both skin and joint outcomes in psoriatic arthritis (PsA) patients who have previously failed treatment with a tumour necrosis factor-α (TNFα) inhibitor.

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