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Full read review and overview of Fibromyalgia - manifestations, pathophysiology, treatments and guidelines. Multidisciplinary, patient-centered treatment should includes a combination of pharmacological and nonpharmacological options. https://t.co/x4OVeQ5RJz https://t.co/i1fD6XQbnx

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Dr. John Cush @RheumNow (  View Tweet)
P2 Trial: DEU in PsA Encouraging results for DCV 6 and 12 mg qd. ACR20 63% for DCV 12 mg (p=0.0004) Not yet FDA approved for PsA, only PsO Pending P3 P2: DEU in SLE - PAISLEY Improved SRI(4), CLASI-50 at w32 Merola #RNL2025 @RheumNow https://t.co/RV7OPaZWjx

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Eric Dein @ericdeinmd (  View Tweet)
Combination therapy in PsA . Regulatory and reimbursement issues may inhibit such strategies (and potential adverse event concerns) but anecdotal evidence would suggest a role in difficult to treat cases. @RheumNow #RNL2025 https://t.co/IIoUiJyP95

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Richard Conway @RichardPAConway (  View Tweet)
MDA5 + Pts with #ILD in #dermatomyositis can improve! ⁦@RheumNow⁩ ⁦@ACRheum⁩ #RNL2025 Data from Christina Charles-Schoeman #ClinicalPearl Her pearls 👇 #DM is a #vascular #disease #CK is not reliable in chronic DM Neg Abs don’t r/o #myositis https://t.co/hxomz70aq5

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Janet Pope @Janetbirdope (  View Tweet)
#RNL2025 @RheumNow Dermatomyositis is VASCULAR disease -IVIG may help DM by blocking complement deposition on endomysial capillaries -CK levels not reliable Pruritus common in up to 86% of DM patients Dr. Charles-Schoeman, UCLA

Eric Dein @ericdeinmd (  View Tweet)

#RNL2025 @RheumNow JAKi in DM: @JuliePaikMD- 10 DM pts open label on JAKi. 7/10 improved from mod/severe to mild. In 96wk extension, 6 of 7 continued response 145 case reports for tofa, bari, ruxolitinib. Role in helping calcinosis? Pruritu? Brepocitinib (JAK1/TYK2i) study

Eric Dein @ericdeinmd (  View Tweet)

Pearls on Dermatomyositis: -Negative myomarker does not r/o DM -Pruritus can be a skin manifestation in DM🚨 -Combination therapy upfront =achieve faster remission -Evidence for JAK inhibitors in management -JAKis seem to have good effect in DM-calcinosis -In DM with rapidly… https://t.co/J3iiDa6ph7 https://t.co/0WTHKa97bt

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Adela Castro @AdelaCastro222 (  View Tweet)
Importance of not over-relying on lab tests. We can test for what we can test for, but this is not comprehensive. For me in clinical practice - Postive antibodies can confirm diagnosis of DM but negative cannot exclude it. @RheumNow #RNL2025 https://t.co/Kyfzne4BSD

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Richard Conway @RichardPAConway (  View Tweet)
Do you want to know a secret? @drcharitydean shares that doctors are wired in the same way that #AI is built. We understand the layers of complexity & are best equipped to partner with AI. @rheumnow #RNL2025

TheDaoIndex @KDAO2011 (  View Tweet)

"Treat for the most likely, mitigate for the catastrophic" @drcharitydean (my hero!). Read her story in "Premonition" by Michael Lewis. She served an impt role in the COVID19 pandemic as a public health officer for CA. Her lecture is on re-inventing yourself. @rheumnow #RNL2025 https://t.co/3ZWgClzez1

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TheDaoIndex @KDAO2011 (  View Tweet)
#HOT #topic Will #Rx of #PsO PREVENT onset of #PsA Well, maybe 🤔 Alexis R Ogdie ⁦@RheumNow⁩ #RNL2025 70% of #psoriatic #arthritis is preceded by #psoriasis Still a bit of a debate re prevention of PsA https://t.co/7bce8kcjdr

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Janet Pope @Janetbirdope (  View Tweet)
Risk factors for development of PsA in psoriasis. Psoriasis severity, obesity, and depression. @alexisogdie @RheumNow @RNL2025 https://t.co/obMDBvLLnx

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Richard Conway @RichardPAConway (  View Tweet)
Great graph from @AlexisOgdie on the effect of biologic treatment on PsA development in psoriasis. Obvious front-loading in those who need systemic therapy. But over time those who don't appear to develop more PsA @RheumNow @RNL2025 https://t.co/UxUZyKb0NA

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Richard Conway @RichardPAConway (  View Tweet)
Can treatment of PsO prevent PsA? -Severity of PsO and obesity->Risk fx for PsA -PRESTO scores: Predicts whether you will develop PsA in the next year vs next 5 years -Does ttx of PsO impact development of PsA? Trials are mostly observational (several confounders) TriNetX data:… https://t.co/TBv3Y2TLZv https://t.co/1K0MtMQ5gn

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Adela Castro @AdelaCastro222 (  View Tweet)
FDA has approved Journavx (suzetrigine) 50 mg tablets, 1st in-class non-opioid analgesic, to treat moderate to severe acute pain in adults. Journavx reduces pain by targeting a pain-signaling pathway involving sodium channels in the peripheral nervous system, before pain signals… https://t.co/qjtr4yz8Ot https://t.co/RUZmLgsmTv
Dr. John Cush @RheumNow (  View Tweet)
Break a leg! Or a #hip #AVN risk occurs even at 1 month of high / moderate dose #glucocorticoids Shown by Michelle Petri @RheumNow #RNL2025 Risk in SLE is likely 👇 #disease #activity And #steroids #SLE #systemic #lupus #erythematosus #steroids https://t.co/4EsQw9tY1u

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Janet Pope @Janetbirdope (  View Tweet)
Even a #SLE expert who wants all #lupus Pts on No #chronic #prednisone Realizes you can’t get everyone off #glucocorticoids 18% May be on chronic #steroids But she keeps trying to taper Michelle Petri #RNL2025 @RheumNow https://t.co/SNP6Eep731

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Janet Pope @Janetbirdope (  View Tweet)
M. Petri on Steroids in SLE👇 -Organ damage is higher in AA vs Caucasians-driven by CS -CV risk increase is dose dependent: >10 mg =2x risk >20mg =5x risk -Increase prednisone by 10mg =30% increased risk for organ damage! 🤯 -20mg/day >1m increases risk for… https://t.co/fZVjS7JQBL

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Adela Castro @AdelaCastro222 (  View Tweet)

QD Clinic - dsDNA without Lupus Insufficient Sxs to Dx SLE, but persistent dsDNA positivity - what to do? Features Dr. Jack Cush. QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025 Register at https://t.co/2dcFVgu8z6… https://t.co/hCXRhTJB7G https://t.co/y3Tzh5bRLJ

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Dr. John Cush @RheumNow (  View Tweet)
Wise person once said If you don’t take your medications, THEY DON’T WORK! Shocking 1 in 3 nonadherence with #hydroxychloroquine By drug levels In young Pts with #SLE #lupus Michelle Petri @RheumNow #RNL2025 https://t.co/H5izbnW0qU

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Janet Pope @Janetbirdope (  View Tweet)

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  • QD clinics - lessons from the Clinic brought to you by RheumNow Live 2025
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Therapeutic Updates

Autoimmune Myositis: The Role of the Laboratory in Diagnosis and Phenotyping

Sponsored by Labcorp
Labcorp
Hear from rheumatologist Stanley J. Naides MD, FACP, FACR, as he details the clinical features of autoimmune myositis, the associated phenotypes and autoantibodies, plus the methodologies and testing options to support a myositis diagnosis.
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