Arthritis & Rheumatology has published the results of a subanalysis from tocilizumab (TCZ) clinical trials showing that Il-6 inhibition was associated with preservation of lung function patients with early systemic sclerosis (SSc).
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Dr. Jack Cush reviews nearly a dozen news and journal reports from the past 2 weeks on RheumNow.com, including the ACR's new COVID-19 vaccine guidance for patients with rheumatic disease.
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A recent metanalysis of studies suggest you may be able to use certain clinical factors to stratify cancer risk in patients with idiopathic inflammatory myopathies (IIMs).
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The NEJM has reported the results of a study showing that avacopan, a C5a receptor inhibitor, is as effective as steroids at treating patients with antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV).
Analysis of incident #RA in UK Clinical Practice registry shows recent prednisone >=7.5mg/d is assoc w/ hypertension in RA. In 17760 RA pts, 42% were Rx steroids; recent GC yielded a 17% increase in HTN (HR 1.17); only >7.5mg/D implicated https://t.co/qUKs2oZZUV https://t.co/pWmD4nKs6U
QD Clinic - When to do Genetic Testing in Febrile Patients
Indications for Genetic testing for autoinflammatory disorders
https://t.co/1vnR1JQAxZ https://t.co/x2wyLHhjgN
QD Clinic - Hemoptysis and SLE
Key Features of Alveolar Hemorrhage in lupus
https://t.co/qNZYDYmn70 https://t.co/sitc7Tlf5V
RheumNow Podcast is now up! Systemic Sclerosis Pearls
Dr. Jack Cush reviews nearly a dozen news and journal reports from the past 2 weeks on https://t.co/fxtCOkxTER,
https://t.co/nKRmKWR0Bd https://t.co/ESdycxLoCz
High Risk Cancer Profiling with Inflammatory Myositis
A recent metanalysis of studies suggest you may be able to use certain clinical factors to stratify cancer risk in patients with idiopathic inflammatory myopathies (IIMs).
https://t.co/TjmdGtdDQG https://t.co/tlfVU031fY
QD Clinics - Traveling to Medical Meetings during COVID
Is it Safe to Travel?
https://t.co/flELrZbjnw https://t.co/ixebtW71fx
Avacopan - Is it Really a Win for ANCA-Associated Vasculitis?
The NEJM has reported the results of a study showing that avacopan, a C5a receptor inhibitor, is as effective as steroids at treating patients with ANCA-AAV.
https://t.co/vWmhEhX8Z3 https://t.co/omXpouPKoJ
SF analysis usually confirms dx, but changes dx 14%. 264 SF samples showed MSU crystals in 89% gout, 9% of CPPD pts. CPP crystals found in 54% of CPPD, 43% of OA & 7% of gout pts. Ca hydroxyapatite seen 1/3 RA, 1/2 OA & 2/3 CPPD https://t.co/B8UkHagXK3 https://t.co/UTncLo6Fyu
Alveolar Hemorrhage and Mortality in Lupus
Metanalysis of patients with DA), show this to be a rare and life-threatening complication of SLE, that is more apt to affect older, severe lupus patients with active infection.
https://t.co/EILQZTYYjk https://t.co/kDAFuYIJuH
Email Survey study of HSS rheumatic pts 7,094 responded 1,547 were women (18-50yrs) & 61 (4%) were pregnant during COVID. COVID prevalence was similar in PREG vs nonPREG (8% vs.9% ), PREG COVID pts had shorter Sxs, more loss taste/smell. https://t.co/4HDuXbZVrs
2021 RWCS Review podcast is now available- #RWCS Available on SoundCloud and Apple/Android https://t.co/eLk3vqoAT8 https://t.co/U8YjToQlIS
QD Clinic - RA and DVT
Counseling Patients on JAKs and Thrombotic Risk
https://t.co/efQGtkrxHF https://t.co/mfhjZYMlUC
Checkpoint Inhibitor Use with Pre-existing Autoimmune Disease
https://t.co/S9SQVAKJ8q https://t.co/FOjp2Pk61a
Very high levels of IL-18 IL-18 (> 10 000 pg/ml) is associated with Macrophage Activation syndrome (with systemic JIA) as well as primary and secondary Hemophagocytic lymphohistiocytosis (HLH) https://t.co/dotoaYbuPd
On March 24, 2021 the FDA Arthritis Advisory Committee and Drug Safety .... Committees will meet online to will discuss biologics license application, for tanezumab, from Pfizer, for the proposed treatment of moderate to severe osteoarthritis in adults https://t.co/NSlutqdHzu
BU/BMC Rheumatology
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Congratulations again to @Tuhina_Neogi, the newly installed Alan S. Cohen Professor of Rheumatology
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