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A longitudinal observational cohort study of psoriatic arthritis (PsA) patients treated with biologic therapy finds relatively low persistence of selected biologic therapy in PsA patients
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Lancet Rheumatology has reported the results of a proof of concept trial, wherein vagal nerve stimulation was shown to ameliorate RA disease activity. The intervention involved non-invasive stimulation of the auricular branch of the vagus nerve using a wearable vagus nerve stimulation device for up to 30 min per day, delivering pulses of 20 kHz.
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Analysis of the NHANES (National Health and Nutrition Examination Survey) data suggests that one-third of the risk of developing rheumatoid arthritis (RA) in the USA is attributable smoking, obesity and alcohol intake.
Dr. John Cush
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Don’t Hold the Benlysta, Take the Vaccine
The RheumNow podcast is available on Soundcloud, https://t.co/fxtCOkxTER, and Apple/Android car play.
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Dr. John Cush
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Download Available-- Osteoarthritis vs. Rheumatoid Arthritis
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Dr. John Cush
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Consults in Cars--have telehealth consults gone too far?
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Dr. John Cush
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Vagal Nerve Stimulation in Rheumatoid Arthritis
Lancet Rheumatology has reported the results of a proof of concept trial, wherein vagal nerve stimulation was shown to ameliorate rheumatoid arthritis (RA) disease activity.
https://t.co/AuoeDLM5rF https://t.co/8Mv7EYlVWZ
Dr. John Cush
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Low Persistence of Biologics in Psoriatic Arthritis
A longitudinal observational cohort study of psoriatic arthritis (PsA) patients treated with biologic therapy finds relatively low persistence of selected biologic therapy in PsA patients.
https://t.co/CzQnpAnttW https://t.co/uYU778rwod
Dr. John Cush
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QD Clinic - "I Don't Know"--What to Say When you Don't Have a Diagnosis to Deliver
https://t.co/HcJAXRYTyc
Dr. John Cush
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One-Third Rheumatoid Risk from Lifestyle
Analysis of the NHANES data suggests that 1/3 of the risk of developing RA in the USA is attributable smoking, obesity and alcohol intake.
https://t.co/jLLmEvXg2O https://t.co/ZG1hcJ7QVJ
Dr. John Cush
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Download available--Maintaining a Healthy Immune System
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Dr. John Cush
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Abbvie has released data from KEEPsAKE-1 and KEEPsAKE-2 studies (1407 pts) showing Risankizumab (IL--23 inhibitor) is effective in Psoriatic arthritis; RIS Rx pts achieved ACR20 of 57% and 51% at week 24 (vs PBO 34% and 27%; p<0.001) https://t.co/wPQMqLnhOO
Dr. John Cush
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Metanalysis of 24 studies finds pregnant women, w/ inflammatory disease, exposed to biologics had NO increased risk of congenital anomalies (adj OR 1.18; 0.88, 1.57), but had increased preterm births (OR 1.61; 1.37, 1.89) & low birth weight (OR 1.68) https://t.co/KqTDmfFf9H
Dr. John Cush
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French study of 782 men (50-85 years) with DISH found DISH was associated with increased vertebral fractures (OR 2.89; 95% CI, 1.15-7.28; P <.05), but Nonvertebral fractures were not associated with DISH (HR 0.72; 0.33-1.56). https://t.co/YoQ8r62pns
Dr. John Cush
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British registry 801 axial SpA pts; 646 did not hve fibromyalgia at baseline & 46 (7%) developed FM over time. Of 115 axSpa w/ baseline FM, 77 (2/3) recovered. FM more likely with high Dz activity ((OR 1.27) & widespread pain (OR 1.14) https://t.co/4jOdaXIJuB https://t.co/ruOYj5HmMX
Dr. John Cush
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Our Top January Tweet:
Urate Lowering Therapy During Acute Gout
Acute gout has its well-defined protocols, and most state that urate lowering therapy should be continued; but does ULT affect outcomes in an acute gout attack?
https://t.co/aDHpU1qrlu https://t.co/6xDwyVjuyC
Dr. John Cush
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Multiple intraarticular steroid injxs NO better than placebo. Analysis of 6 RCTs show no diff in pain than PBO (−0.47, 95% CI −0.62, 0.31). 14 RCTs + 2 Observ. studies show IA steroids may cause mor cartilage loss or risk of joint replacement (HR 2.54) https://t.co/jCLq4jWn4Y
Dr. John Cush
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Everyone longs for normal. Normal may have changed, died, or been put off. But tomorrow morning, normal is waking up and looking to you for guidance
Dr. John Cush
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Sign up for RheumNow Live, March 20 and 21st. CME credits available.
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Dr. John Cush
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Download our latest resource--Televideo Joint Exam Checklist.
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