Article
T cells are known to play a key role in RA pathogenesis and the diversity of the T cell repertoire is known to be reduced in RA.
All News
Article
There is a clear unmet need for new and effective therapies in primary Sjogren’s Syndrome (pSS) patients, as there are no current licensed therapies.
Article
Day 3 was a sunny warm day in Milan at the 2023 EULAR Congress meeting. Here are a few of my favorite abstracts from today.
Article
The use of artificial intelligence to analyse large data sets using its subset component machine learning has taken centre stage recently in the management of rheumatic conditions, including rheumatoid arthritis. The use of AI is now starting to cross the various stages in patient care from detection, diagnosis, treatment and the prediction of long-term outcome.
David Liew
Tweet
Important from @cappelliMD @jhrheumatology irAE cohort on predictors of DMARD requirement in ICI-inflammatory arthritis, and persistent ICI-IA post-ICI cessation.
The better we can predict these patients, the more we can get the right therapy early
POS0951 #EULAR2023 @RheumNow https://t.co/YGTRl71505
Dr. Antoni Chan
Tweet
EULAR 2023 recommendations on the management of fatigue in IRMDs. 4 overarching principles and 4 recommendations for monitoring and assessment of fatigue, Dures E Abst#P0370 #EULAR2023 @RheumNow https://t.co/AirPlRLNjZ
Dr. John Cush
Tweet
The future of lupus treatment is oral therapies?
There has been an explosion of trials in SLE, including nonrenal and glomerulonephritis studies.
@Janetbirdope
https://t.co/IQ9bxbTSV4 https://t.co/jVYOphxpAE
Aurelie Najm
Tweet
Supervised 12 weeks High-intensity interval training program
Improves Vo2 peak in IA patients
But does not improve pain or fatigue
It is disappointing but it is also a small study w/ n=30 pts in each group.
It is unclear if the type of exercise has an impact on outcome https://t.co/Plk7sflrh5
Aurelie Najm
Tweet
What happens when an AI-based symptom checker & an online self-referral tool play Rheumatologists?
They don't seem to do great yet!
600 new pts, outw/ 36% dvlpd IA
IA Sens 62% Spe 47%
Tool Sens 66% Spe 54%
More work needed to implement these in practice
#EULAR23 @Rheumnow
Dr. John Cush
Tweet
AOSD: Young vs. Elderly Onset
AOSDis an autoinflammatory condition characterized by fevers, arthritis, and rash. It is considered an orphan disease because of its low prevalence - it is reported anywhere between 16 to 40 per ten million.
https://t.co/PPI1fvwLAf https://t.co/qMXMsbpwl3
Md Yuzaiful Md Yusof
Tweet
#EULAR2023 Clinical Highlights. Osteoarthritis. OP0071 Single centre Phase 2 RCT showed Denosumab halted erosion in Erosive OA at 24 weeks treatment, and the treatment effect enhances after 48 weeks vs PBO @RheumNow https://t.co/YWFUg3cp7P
Aurelie Najm
Tweet
Adherence to TNFi follows different trajectories
Cluster 1: “moderate then high” 51%
Cluster 2: “moderate then low” 20%
Cluster 3: “low adherence, to discontinuation” 18%
Cluster 4: “low then high adherence” 11%
Most demographic & clinical features CAN NOT predict trajectory! https://t.co/4wLg6b70Kl
Dr. Antoni Chan
Tweet
Late Breaker - EULAR 2023 update on imaging of large vessel vasculitis. Ultrasound is now recommended as first line imaging test in all patients with suspected GCA, and axillary arteries should be in the standard examination, Dejaco C et al, Abst#LB0009, #EULAR2023 @RheumNow https://t.co/ya41nJG6qK
Dr. Antoni Chan
Tweet
Late Breaker - Cardiorespiratory fitness increased in patients with IJD after 12 weeks of supervised
HIIT and effect maintained at 6 months. No significant differences in pain and fatigue vs control. HIIT is a viable intervention Norden K Abst#LB0007 #EULAR2023 @RheumNow
Aurelie Najm
Tweet
2023 update @EULAR recommendations imaging in GCA
What's new:
1. US = first line imaging test
2. Axillary arteries should be included in standard examination
3. Alternative imaging FDG-PET or MRI
4. Takayasu: MRI preferred CT or FDG-PET alternatives
@Rheumnow #EULAR23 LB0008 https://t.co/rGPfOPX1gI
Md Yuzaiful Md Yusof
Tweet
#EULAR2023 Clinical Highlights. CTD: OP0240 Open label study (N=26) showed stabilisation/improvement in FVC in patients with #ILD treated either Tacrolimus vs MMF. No efficacy difference between both therapies @RheumNow https://t.co/d3rCzNgYHK
Bella Mehta
Tweet
With the single cell RNA sequencing analysis being my more affordable (relatively) and widely used! Science is moving forward. Highlights in basic science and translational data #EULAR2023 @RheumNow https://t.co/sS7xLeNyLW
Janet Pope
Tweet
I hurt because the weather is COLD! Data from Rhumadata in 14000 pt encounters show higher pt GLOBAL in winter vs summer - NB cold in Quebec #EULAR2023 POS0324 @RheumNow Small differences but maybe a script to go south is the right Rx! https://t.co/tjd6FjEHij
David Liew
Tweet
Which bDMARD first in PsA?
2023 @eular_org recommendation: no preferred order. All are equal in its eyes
#EULAR2023 @RheumNow https://t.co/6HNNamAj1J
David Liew
Tweet
It might not be perfect, but it’s just great to have a dynamic poster floor back #EULAR2023. The heartbeat of the meeting!
(this was near the end on the last day - it’s been properly hectic throughout) @RheumNow https://t.co/jPGO5dylvg
