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FDA issued Drug Safety Communication to statin manufacturers requesting they remove strong warnings against statin use during pregnancy. While statins appear in breast milk, they should not be contraindicated, if needed, during Pregnancy https://t.co/AeFwpsLMXT

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Dr. John Cush RheumNow ( View Tweet)

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RheumNow Podcast – Saphnelo (Anifrolumab) Approved for Lupus (8.6.2021)

d Jack Cush, MD

It was a banner week at the FDA; a new drug approval you should know about; a lot of information about pregnancy and safety; and an interesting case plus a question from one of our readers submitted via Back Talk. This and more in this week's podcast. Let's dive in.

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kids,learn,book

Rheumatoid Arthritis Offspring Show Normal School Performance

d Jack Cush, MD

A prospective, longitudinal study of the cognitive development of children born to mothers with rheumatoid arthritis (RA) demonstrates normal development as measured by comparative school test scores.

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CMAJ: nice full read review of biologic use during pregnancy. 1) autoimmune/arthritis pts may use biologics during pregnancy 2) mom/infant should avoid live vax 1st 6–12 mos 3) Minimal biologic transfer in breast milk 4) no risk of congenital anomalies https://t.co/mlZTrDjXSi

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Top Tweet Last Week: Potential Birth Defects with Hydroxychloroquine HCQ is one of the safest meds used in rheumatology, but there is new claims data suggesting a small increase in the risk of malformations associated with first-trimester HCQ use. https://t.co/IHNKjHVXaU https://t.co/Oay2ayVr9m

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Dr. John Cush RheumNow ( View Tweet)
Survey of women re: sex & reproduction (SRH) says women prefer 1) Rheums to initiate SRH discussions, 2) clear info on pregnancy & infertility risks w/ Dz & DMARDs, 3) holistic Rx approach, 4) not to be intermediaries betw Rheum & OB https://t.co/Orlh6gLO6P https://t.co/rS4r39Easx

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Dr. John Cush RheumNow ( View Tweet)
fetus,defect,baby,malformation

Potential Birth Defects with Hydroxychloroquine

d Jack Cush, MD

Hydroxychloroquine (HCQ) is one of the safest meds used in rheumatology, but there is new claims data suggesting a small increase in the risk of malformations associated with first-trimester HCQ use.

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ICYMI: RheumNow Podcast – Tofacitinib Safety Concerns

d Jack Cush, MD

Dr. Jack Cush reviews and discusses the news and journal reports from the past week on RheumNow.com.

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2020 Year Review

ICYMI: 2020 Rheumatology Year in Review

d Jack Cush, MD

2020 was historic, memorable and game-changing. Under the cloud of COVID-19, there were many significant and memorable advances and setbacks for the rheumatology world. In our accounting of most read articles for 2020, (not surprisingly) 17/20 were COVID-related.

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Metanalysis of 9 studies, and 1132 lupus pregnancies shows that hydroxychloroquine treatment significantly reduced the risk of preeclampsia (OR 0.35), pregnancy hypertension (OR0.41)and prematurity (OR 0.55), but no effect on rates of HELLP, DM, Ab https://t.co/P9MXjDpuiO https://t.co/DxVWiUAPpe

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Dr. John Cush RheumNow ( View Tweet)
With the expansion of knowledge regarding the safety of newer agents in pregnancy comes the PreCARA study showing that when pregnancy is planned and patients with RA are treated with a modified T2T approach, superior outcomes can be anticipated. Read on: https://t.co/sV5hJRzPJW https://t.co/ADppVd3CmZ

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Dr. John Cush RheumNow ( View Tweet)
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RheumNow Podcast – Modern Treatment of RA Pregnancy (6.25.2021)

d Jack Cush, MD

Dr. Jack Cush reviews this week’s news and journal reports featured on RheumNow.com.

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hands pregnant

Better Outcomes with Modern T2T in Pregnancy

d Jack Cush, MD

With the expansion of knowledge regarding the safety of newer agents in pregnancy comes the PreCARA study showing that when pregnancy is planned and patients with rheumatoid arthritis (RA) are treated with a modified treat-to-target (T2T) approach, superior outcomes can be anticipated.

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What's the impact of RA on male fertility? Dr. Aurelie Njam shares new data provided at #EULAR2021. https://t.co/AHwhyLiwD0 https://t.co/pFKoADZ2sh

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Dr. John Cush RheumNow ( View Tweet)
Rheumatoid arthritis in either partner can affect fertility and pregnancy outcomes. Dr. Kay discusses abstract OP0210, abstract OP0212 and abstract OP0211 presented at the virtual EULAR meeting. https://t.co/Y9uVBGmxcP https://t.co/YVz08q67gc

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Dr. John Cush RheumNow ( View Tweet)
What about Babies of Patients with Inflammatory Arthritis? Dr. Janet Pope ( @Janetbirdope) shares the results from study OP0211. #EULAR2021 https://t.co/odLknwNlMv https://t.co/AmsaSg9Gwe

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Dr. John Cush RheumNow ( View Tweet)
pregnant, pregnancy, mother, fertility

Current approach to lupus and pregnancy

d Robert Chao, MD

All of us are extremely cautious with lupus patients when it comes to pregnancy. Presentation 6888 (Common issues in pregnancy management in lupus and anti-phospholipid syndrome by Dr. Rebecca Fischer-Betz) was an excellent overview of our current approach to lupus and pregnancy. 

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This three minute video is a great watch-- is Cetrolizumab safe in pregnancy? Dr. Kathryn Dao ( @kdao2011) shares learnings from #EULAR2021. https://t.co/Tx4TLr4J1Y https://t.co/rOVBqX07hc

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Dr. John Cush RheumNow ( View Tweet)
Video: Impact of RA on Male Fertility: New Data: Dr. Aurelie Najm Dr. Aurelie Najm reviews abstracts OP0211 and OP0212 presented at the virtual #EULAR2021 meeting. https://t.co/AHwhyLiwD0 https://t.co/sm7cSBPIBV

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Dr. John Cush RheumNow ( View Tweet)
Current approach to lupus and pregnancy by Dr. Robert Chao ( @doctorRBC) #EULAR2021 https://t.co/eFd6j9YZo5 https://t.co/tW9tJIRpjm

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Dr. John Cush RheumNow ( View Tweet)

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