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#RNL2024
@RheumNow
ASCVD Risk Calculators underestimate risk in patients of RA
Inflammatory disease was added as a "risk enhancer" in 2019 update
"A low ASCVD and/or absence of symptoms may be not be reassuring" https://t.co/XjTuzvvO4v
Links:
Eric Dein ericdeinmd ( View Tweet)
Why is improved plaque identification important?
1. Most stress tests are normal!
2. Most events occur in pts with normal function studies
3. Plaque burden predicts risk, better than stenosis
Dr. B. Weber #RNL2024 @RheumNow https://t.co/Qs19qIYj5v
Dr. Rachel Tate uptoTate ( View Tweet)
ICYMI: new guidelines published in 2019 for CV prevention. It's important to assess CV risk in our patients because inflammatory diseases is now included as a risk factor (helps when deciding on starting pts on JAKi)- Dr. B Weber #RNL2024 @RheumNow https://t.co/nBQjs49avu https://t.co/apyDjaxudi
Links:
TheDaoIndex KDAO2011 ( View Tweet)
Primary ASCVD Prevention Guidelines for your reference from Dr. B. Weber. #RNL2024 @RheumNow https://t.co/erxIgeeLNU
Dr. Rachel Tate uptoTate ( View Tweet)
Dr. B. Weber's review of the 2019 ASCVD risk factors which now includes inflammatory diseases (RA, HIV, PsO).
She believes this will help us to better understand and grow our knowledge around patient risk. @RheumNow #RNL2024 https://t.co/9bV7VfExNf
Dr. Rachel Tate uptoTate ( View Tweet)
Nuclear imaging assesses cardiac function, anatomy & microvascular dysfunction (MD). MD is underrecognized but can be measured by coronary flow reserve. MD is associated with worse longterm outcomes in systemic inflammatory disease – Dr. Weber #RNL2024 @rheumnow https://t.co/Bv22UKi6mM
Links:
TheDaoIndex KDAO2011 ( View Tweet)
Coronary Microvascular Dysfunction is associated with poor prognosis/outcomes in our systemic inflammatory disease patients.
What is the gold standard for evaluating microvascular dysfunction?
Coronary Flow Reserve (CRF)
This is only one component to fully understand and assess… https://t.co/bMV5npkFwm https://t.co/ZYBXpQLPIF
Links:
Dr. Rachel Tate uptoTate ( View Tweet)
Link between inflammation and cardiovascular disease, increased 1.5x in RA and 2-3 in PsA, treating inflammation is important to reduce CV risk, Brittany Weber #RNL2024 @RheumNow https://t.co/FCrOxa3drZ
Dr. Antoni Chan synovialjoints ( View Tweet)
Dr. B Weber gave a wonderful review of inflammation and cardiac risk in SLE, PsO/PsA, and RA.
*SLE pts has a 50-fold increased risk of MI
*RA pts are a 1.5x risk of CVD
*PsO and PsA pts are also at increased risk for CVD
#RNL2024 @RheumNow https://t.co/Hy4TmLzhzO
Links:
Dr. Rachel Tate uptoTate ( View Tweet)
"The link between RA and CVD is the shared inflammatory pathways involving IL-1, IL-6 and TNF" -Dr. B Weber #RNL2024 @rheumnow https://t.co/aGPA8ZFNHj
TheDaoIndex KDAO2011 ( View Tweet)
CV disease risk is increased in patients with inflammatory rheumatic diseases. More data emerging in SLE, psoriasis, RA. – Dr. B Weber #RNL2024 @rheumnow https://t.co/wF9izGZug3
Links:
TheDaoIndex KDAO2011 ( View Tweet)
#RNL2024 @RheumNow
Weber:
Asymptomatic Lupus has higher rate of atherosclerosis at all age grps
35-44 yo F with SLE: 50X increased risk of MI compared to healthy pts in Framingham
RA pts at 1.5x risk of CVD https://t.co/TJ5dLXwvNc
Links:
Eric Dein ericdeinmd ( View Tweet)
#RNL2024 @RheumNow
Brittany Weber on Cardio-Rheumatology:
"Everything has changed" on inflammation and CVD
- Canakinumab 150 mg v PBO HR 0.85, p =0.02
- Colchicine v PBO HR 0.69, P<0.001
2023: FDA approval for colchicine as 1st anti-inflammatory for reducing CV events https://t.co/Tlv5Np2BHf
Eric Dein ericdeinmd ( View Tweet)
Check out some of the "newer" modalities available to us for evaluation of our rheumatology patients to better understand their cardiac risk. "Everything has changed in cardiac rheumatology." Dr. B. Weber #RNL2024 @RheumNow https://t.co/fki73W4Fk8
Dr. Rachel Tate uptoTate ( View Tweet)
Dr. B Weber discusses new CV Imaging Tools beyond the exercise EKG and ECHO to assess our rheum patients who are at higher risk for CV disease: coronary CT, Stress CMR, stress PET #RNL2024 @RheumNow https://t.co/DAuUptHMuF
TheDaoIndex KDAO2011 ( View Tweet)
Dr. Brittany Weber showcases the diverse manifestations that we can see in rheumatology and the increasing complexity and use of imaging in field. #RNL2024 @RheumNow https://t.co/0dOJdPazXL
Dr. Rachel Tate uptoTate ( View Tweet)
Ready to get your #GameOn at #RNL2024 @RheumNow https://t.co/joP1xcU0TH
Dr. Rachel Tate uptoTate ( View Tweet)
Starting now - #RNL2024 w @RichardPAConway @RheumNow
Today's Pods: RA - nutrition! prevention!
PsA -@AlexisOgdie on guidelines! Gender differences JAKs -@JointMD and Kevin Winthrop on use and safety SLE - @andreafava on biomarkers
Plus @BharatKumarMD on appreciative rheum
Eric Dein ericdeinmd ( View Tweet)
#RNL2024 has started- not too late to register:
https://t.co/esqYcqSvbP
@RheumNow and Dr A Kavanaugh https://t.co/d6EQFI9rTT
TheDaoIndex KDAO2011 ( View Tweet)
Starting now - #RNL24 w @RichardPAConway
@RheumNow
Today's Pods: RA - nutrition! prevention!
PsA -@AlexisOgdie on guidelines! Gender differences JAKs - @JointMD and Kevin Winthrop on use and safety SLE - @andreafava on biomarkers
Plus @BharatKumarMD on appreciative rheum
Eric Dein ericdeinmd ( View Tweet)