Chronic Kidney Disease Augments Gout Risks Save
A population based cohort analysis shows that patients with incident gout and chronic kidney disease (CKD) have far worse outcomes than those without CKD.
A retrospective population-based cohort study of incident gout between 2006-2009 identified those with CKD; defined as a pre-existing diagnosis of chronic kidney disease, chronic renal failure, kidney transplantation, or dialysis at index date.
Among 12,940 incident adult gout patients, 64% with CKD and 36% without CKD, were followed for 55,206 person-years.
Overall, gout patients with CKD (vs those without CKD) had:
- Significantly more healthcare utilization; Hospital admissions were at least 3 times higher for Gout+CKD adults
- All-cause mortality was higher among those with CKD compared to those without CKD for both age groups (HR
Gout plus CKD constitutes a high risk population that merits focused efforts to better control their gout and optimize comorbidity management.