Weight Loss Improves Psoriasis

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Jennsen et al previously reported their findings regarding weight reductions ability to improve cutaneous psoriasis at the European Academy of Dermatology and Venereology (EADV) meeting in 2015, Now their results are published in The American Journal of Clinical Nutrition.

Pregnancy Outcomes in Psoriatic Arthritis

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Disease Activity Pre-pregnancy During Pregnancy Post-pregnancy
Mild 10 6 4
Moderate 2 6 8
Severe 2 2 2

Biopsy Proven Renal Involvement in Sjogren's Syndrome

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A French multicenter study of primary Sjogren's syndrome (pSS) patients fulfilling the American–European Consensus Group criteria or enlarged American–European Consensus Group criteria were retrospectively studied based on having biopsy-proven renal involvement.

DMARDs Under Study for Secondary Prevention of Cardiovascular Events

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Several important lines of population and large cohort research have shown that rheumatoid arthritis (RA) patients have a substantially higher risk for myocardial infarction and major cardiovascular events.

Cautious Optimism for Biosimilars in Rheumatology

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BEST-D Trial: Higher Doses of Vitamin D may be Required for Optimal Osteoporosis Prevention

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Osteoporosis is a major public health problems and is associated with a high burden of fractures and subsequent increased mortality.

Risk of GI Perforations on Biologics

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Gastrointestinal perforation is a rare but serious complication that RA patients may be at particular risk for.

Osteoporosis 2016 Year in Review - No new drug approvals, and a crisis in care

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No new osteoporosis drugs hit the market this year, but two are progressing through the development pipeline and are showing promise.

Female Physicians are Better in Death, Hospital Readmission Stats

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Do hospitalized Medicare beneficiaries treated by female internists have lower rates of 30-day mortality and hospital readmission than those patients treated by men? A new study published online by JAMA Internal Medicine suggests that they do.

EULAR 2016 Recommendations on Early Arthritis

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Combe and leading European rheumatologist have published an update to the 2007 European League Against Rheumatism (EULAR) recommendations for management of early arthritis.

Lupus May Be at Increased Risk for Dementia

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Neuropsychiatric manifestations of systemic lupus erythematosus (SLE) may occur in up to half of patients in their lifetime.

However, dementia is often not reported or studied in cohorts with neurologic disease in lupus. 

Rituximab May Reduce Mortality Risk in Rheumatoid Lung Disease

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While it is known that rheumatoid arthritis (RA) patients with interstitial lung involvement is associated with severe seropositive disease and is associated with an increased mortality.

CanVasc Recommendations for ANCA-Associated Vasculitis

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ANCA associated vasculitis (AAV) has undergone considerable study and advances in the last few years.

Nonsignificant CV Risk with Actemra vs Enbrel

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WASHINGTON -- Rheumatoid arthritis is a recognized risk factor for heart attacks and stroke, but a study comparing two leading biologics found only a non-significant increase in relative risk for patients treated with toclizimab (Actemra) vs etanercept (Enbrel), researchers reported here.

Key Lessons from the TNF Inhibitor Head-to-Head EXXELERATE Study

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The EXXELERATE study is featured prominently in Lancet this week. In some ways, this represents a landmark negative trial that rheumatologists should review and be aware of.

Is ABT-494 the Next JAK Inhibitor?

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Tofacitinib may well be joined by a new once daily JAK inhibitor, baricitinib in the next few months.

The RheumNow Week in Review – 2 December 2016

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Dr. Cush highlights reports from this week on RheumNow.com.

ASDAS Activity Correlates with Xray Progression in Spondyloarthritis

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Investigators analyzed a prospective study of patients with early axial spondyloarthritis (axSpA) to assess predictors of outcome.

Diffuse Cutaneous Systemic Sclerosis: Results of the SCOT Trial

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Diffuse cutaneous systemic sclerosis (dcSSc) is one of the most difficult autoimmune diseases to treat. In case of major organ involvement (lung, kidney), prognosis is poor and treatment options are limited.

Maintenance of Remission in ANCA-vasculitis: MAINRITSAN study.

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It is well known that ANCA-associated vasculitides can be hard to control and relapses are common. The choice of maintenance therapy is rather limited and therapies are not always effective.