Autoimmune Disease Clustering at ENDO 2019

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A twin registry database study was presented at the Endocrine Society's annual meeting (ENDO 2019) in New Orleans, showed that that having autoimmune disease significantly increases the risk of other autoimmune disorders and that autoimmune clustering was highest in Addison's disease and vit

Resistant Hypertension Common in SLE

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Rates of resistant hypertension were doubled among patients with systemic lupus erythematosus (SLE), significantly increasing their mortality risks, a retrospective single-center study found.

Improved Mortality Trends in Lupus Nephritis

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The mortality rate from end- stage renal disease (ESRD) in lupus nephritis (LN) patients has significantly decreased in the last decade.

Risky Painkillers Commonly Prescribed for Osteoarthritis

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Published guidelines warn that treating osteoarthritis (OA) with opioids and benzodiazepines can boost patients' risk of falling.

CRA Position Statement on Medical Cannabis Use

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Courtesy of the Canadian Rheumatology Association (CRA) website, here are consensus guidelines on medical cannabis use.

Rheumatology patients experience prevalent pain that is only modestly controlled with current treatment strategies.

RheumNow Podcast – You Owe Me a DEXA (3.15.19)

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Dr. Jack Cush reviews this week's news and highlights from RheumNow.com.

Lower TNF Inhibitor Persistence in Spondylitis

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A claims data analysis shows that only one-third of ankylosing spondylitis (AS) treated with tumor necrosis factor inhibitors (TNFi) therapy remain on their initial drug in the 2 years post initiation.

First Line IL-1 Inhibition in Systemic JIA

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First-line treatment of systemic juvenile idiopathic arthritis (JIA) with anakinra (Kineret) was highly effective as monotherapy, minimizing the need for glucocorticoids, a single-center prospective study found.

2018 Swedish Guidelines for Giant Cell Arteritis Treatment

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The Swedish Society of Rheumatology has developed evidence-based guidelines for the management of giant cell arteritis (GCA) with a focus on the appropriate use of corticosteroids and tocilizumab. 

Multiple Delays in Referral of New RA Patients

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A UK study of early onset arthritis or new rheumatoid arthritis patients shows multiple sources of delayed referral to the first rheumatology consultation.

Biologic Agents have Equal Efficacy in Enthesitis and Dactylitis

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A systematic review has shown that TNF inhibitors (TNFi) are equaled in efficacy by other biologic agents (ustekinumab, secukinumab, and ixekizumab) in psoriatic arthritis (PsA) patients with in dactylitis and enthesitis.

Lower Mortality Results from Lower Activity in Lupus

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Data from the longitudinal Tromsø Lupus Cohort study has shown that lupus patients who achieve a Lupus Low Disease Activity State (LLDAS‐50) were shown to have significantly less severe damage, and a reduction in mortality.

This was a population‐based study of SLE patients in the northern‐most counties of Norway.

Dual IL-17 Inhibitor in Psoriasis Succeeds

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Patients with moderate-to-severe plaque psoriasis attained durable complete and near-complete responses for more than a year with a dual inhibitor of interleukin (IL)-17, data from a randomized trial showed. 

AAD/NPF Guidelines on Biologic Use in Psoriasis

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Menter and colleagues from the American Academy of Dermatology (AAD) and National Psoriasis Foundation (NPF) have published their expert consensus guidelines for the use of biologics in psoriasis.

Dermatology Guidelines for Psoriatic Comorbidities

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The JAAD has published joint guidelines from the American Academy of Dermatology (AAD) and National Psoriasis Foundation (NPF) on the approach, management and dermatolgist roles for select comorbid conditions. 

RheumNow Podcast – Scleroderma and the Lung (3.1.19)

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Dr. Jack Cush Reviews the news and journal articles from the past week on RheumNow.com

Early TNF inhibition in Early Psoriatic Arthritis

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A small, double-blind, randomised, placebo-controlled trial in early psoriatic arthritis (PsA) has shown that first-line use of golimumab and methotrexate (MTX) is superior to MTX alone in inducing remission in PsA.

Allopurinol Reduces Cardiovascular Outcomes in Diabetes

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A Canadian study has shown that elderly diabetics who take allopurinol have a significant reduction in cardiovascular outcomes.  

Does Smoking Cessation Reduce RA Risk?

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Individuals who quit smoking and maintained their nonsmoking status over a long duration of time had a decreased risk of developing seropositive rheumatoid arthritis (RA), an analysis of two large prospective cohorts found. 

RheumNow Podcast - Death and Surgery (2-22-19)

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Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com: