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ACR20 - Day 4 Report
Here are my highlights from day four, Monday, of the ACR 2020 Convergence.
Vaccine Immunogenicity with Tofacitinib
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New podcast out now on our site #ACR20
Mid-Meeting Recap: Psoriatic Arthritis, Gout Patient Outcomes on Low-Dose Steroids, Giant Cell Arteritis Panel Vaccination w/ Shingrix: Does it work for patients on JAKi? Is it safe?
https://t.co/roc1Qjec5R https://t.co/gSkkj2Kl0m
Links:
Dr. John Cush RheumNow ( View Tweet)
📌 #ACR20 Checkpoint Inhibitors: Past, Present and Future
👉close surveillance ➡️ early detection of iRAEs➡️ early treatment➡️ reversibility or ⬇️severity
#ACRAmbassador https://t.co/AM2mfYmAtI
Elizabeth Graef SituationRheum ( View Tweet)
"The goal of a vaccine is not just to protect a (vaccinated) individual, but to end the pandemic." Dr. Dan Barouch #ACR20 @RheumNow
Dr. Rachel Tate uptoTate ( View Tweet)
Interesting Swedish abstract 1997 at #ACR20. Adjuvant #herpeszoster vaccine (Shingrix) not effective for 25% of JAKi-treated RA pts (n=40) for antibody response (T cell response usually worse, not reported). Is better than nothing good enough? Maybe we need to hold JAKi briefly?
Jeffrey Curtis RADoctor ( View Tweet)
Just watched David Beck’s talk on somatic mutations in VEXAS. Genotyping to link phenotypically diverse disease. Such an exciting strategy to identify additional unknown diseases!!! #ACR https://t.co/gU9HEZyjRP
Adam J Brown AdamJBrownMD ( View Tweet)
Prelim. results: Immunogenicity of adjuvanted #HerpesZoster subunit #vaccine in #RheumatoidArthritis patients taking #JAKinhibitors
- Most RA pts on JAKi have sufficient antibody response to HZ vaccine
- Acceptable safety profile
Abs#1997 #ACR20 @RheumNow
https://t.co/8HWAIwOATD
Mrinalini Dey DrMiniDey ( View Tweet)
Just a reminder:
inflammatory arthritis irAEs can occur at almost any time after immune checkpoint inhibitor cancer immunotherapy is commenced.
@LoyolaChicago #ACR20 ABST1566 @RheumNow https://t.co/qdEpNpzdNs
David Liew drdavidliew ( View Tweet)
Dr Kaellmark reports on immunogenicity of adjuvant herpes zoster subunit vaccine in RA patients treated with JAKi. 40 RA patients and 20 controls. Satisfactory serological responses and tolerability seen. @rheumnow #ACR20 Abstr#1997 https://t.co/UlDe4NllU0
Richard Conway RichardPAConway ( View Tweet)
Dr Winthrop reports on rates of influenza in RA in tofactinib clinical programme over 14-15 seasons. No significant differences in rates between tofa, ADA, MTX, and placebo. @rheumnow #ACR20 Abstr#L04 https://t.co/8RrG0I2Zwm
Richard Conway RichardPAConway ( View Tweet)
Retrosp study in France compared MRIs of 96 pts w/ SpA (65% w/ IBP) vs 104 w/o (25% w/ IBP):
- 65% of pts w/ SpA had bone marrow edema (BME) mainly in the iliac quad of intermed middle segment
- 20% w/o SpA had BME mainly in antero-middle quad. #Abst1535 #ACR2020 @RheumNow https://t.co/1ptGGUbUS4
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
How often do you perform NFC in suspected SSc patients? @RheumNow #ACR20
sheila RHEUMarampa ( View Tweet)
Our RA patients are susceptible to a dangerous virus which runs rampant, but won't take the vaccine.
Why won't patients have their flu shot? @McGillMed 40% hesitant despite public funding. Multiple levels influence; if we don't address, our pts suffer!
#ACR20 ABST1740 @RheumNow https://t.co/1Yhr6I2L30
David Liew drdavidliew ( View Tweet)
I just reviewed the #ACR20 talk regarding vaccination. Highly recommended/timely given data released from Pfizer today regarding the COVID-19 vaccine trial. @RheumNow
Pfizer’s Early Data Shows Vaccine Is More Than 90% Effective - The New York Times https://t.co/Fb5ZepCBeJ
Dr. Rachel Tate uptoTate ( View Tweet)
Why care about Sleep? Sleep & Its Immune implications
#ACR20 https://t.co/hUXPiKc1Kg
Dr Irwin Lim _connectedcare ( View Tweet)
Are you talking RA patients about vaccination? Abst#1465 shows S pneumonia vaccinations decreases pna by nearly half in <65 yo, as well as effectiveness in elderly. Theme of day: approach ifn and CV risk are best rheum interventions! @Rheumnow #ACR20 https://t.co/ZilXfFWTUM
Eric Dein ejdein1 ( View Tweet)
Congrats @sdlcrodriguez on a great presentation!
Abs#1465: Combined #vaccination scheme leads to decreased incidence of Strep pneumoniae #infection in #rheumatoidarthritis patients taking b/tsDMARD.
#ACR20 @RheumNow
https://t.co/EwIj0PYbgI https://t.co/cqg8xtcB48
Mrinalini Dey DrMiniDey ( View Tweet)
Learning about the autosomal dominant genetic disease COPA syndrome, a mimic of various rheumatic diseases. Also having the chance to view some fascinating radiological imaging!
#ACR20 @RheumNow https://t.co/sNEGBA6Dbd
Mrinalini Dey DrMiniDey ( View Tweet)
The country/world is in crisis surrounding #COVID19 and today we will ask the tough questions re the what ifs of COVID vaccines - join us at #ACR20 @AWIRGROUP @UnitedRheum @rheum_covid @DrSwamyV @CCalabreseDO @VickiShanmugam @HealioRheum @RheumNow https://t.co/t6s3SHz6K9
Leonard Calabrese LCalabreseDO ( View Tweet)
Be sure to visit https://t.co/70dpxhNDQg to get more information regarding vaccine trials and other science updates! Dr. Fauci #ACR20 @RheumNow https://t.co/ZQUApywGe6
Dr. Rachel Tate uptoTate ( View Tweet)
