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Blau Syndrome - the Prototypic Autoinflammatory Granulomatous Disorder
The defining triad of Blau's syndrome includes granulomatous polyarthritis, dermatitis and uveitis. This rare, monogenic, autosomal dominant disorder stems from a "gain in function" mutation of the pattern recognition receptor NOD2.
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The Risk of Listeriosis in RA
In the mid-1990s, our Rheumatology Division at the University of Texas Southwestern Medical School became involved with an early trial of a brand new TNF inhibitor.
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HLA-DRB1 Alleles Augment RA Severity and TNF Inhibitor Responses
The HLA-DRB1 haplotype is a known risk factor for RA.
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