Periodontal disease (PD) is more common in rheumatoid arthritis (RA), especially those with anti-citrullinated protein antibodies (ACPAs). RA activity has been linked to the severity of PD and mucosal inflammation.
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Which Meds are Best for Acute Low Back Pain?
EurekAlert!
Acute low back pain (LBP) is a common cause of disability. An analysis in the Journal of Orthopaedic Research examined which non-opioid drugs are best for treating this condition.
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Wang et al., in a JAMA Network Research Letter, recently reviewed Medicaid expenditures on adalimumab (ADA), sold under the brand name HUMIRA®. They noted that the introduction of the citrate-free formulation cost an extra $4.4B to Medicaid between 2014 and 2021.
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The etiology of arthritis was studied using US National Health and Nutrition Examination Survey (NHANES) data and suggested that elevated concentrations of trace elements (TE: Pb, Cd, and Cu) were associated with increased risk of arthritis.
New Drug Formulations – For Patients or Profits?
Wang et al in JAMA Network Research Letter, reviewed Medicaid expenditures on ADA, noted that the introduction of the citrate-free formulation cost an extra $4.4B to Medicaid from 2014-2021.
https://t.co/W1sst12GJK https://t.co/OYLkSHEQ2X
32 men w/ B27+ #AS (Rx NSAIDs, BASDAI ~5.3) underwent exercise training (10d, 60min) w/ or w/o Pre-Rx w/ whole-body cryotherapy (WBC). WBC had significant drops in hsCRP, sP-Selectin, sVCAM-1, neopterin & signif decreases in BASDAI, BASFI, pain intensity https://t.co/8bmjTS4VOk https://t.co/ajrD8Z7C8v
Overview of Juvenile idiopathic arthritis (JIA) assoc uveitis (JIA-U) seen in 10–15% ofJIA pts, higher risk w/ ANA+, oligo-JIA, f& onset ≤6 yrs age. Rx options: topical steroids, MTX, ADA, INFLX, RTX and TCZ (review of TCZ in JIA-U) https://t.co/DIccOVLrmR https://t.co/6QD6g6orkp
A retrospective study from a Taiwan health insurance claims data analysis looked at the association between Hashimoto's thyroiditis and lupus.
https://t.co/159JNLY6tf https://t.co/JxR88a84MN
Chest Pain & Fever
Lessons from the clinic,
brought to you by https://t.co/4UQlqwujiR March 18 &19, 2023 - Dallas, TX
https://t.co/k98wmxxG2k
Raynaud's Phenomenon: Now You See Me, Now You Don't
Manmeet Kaur, MD, presents at RWCS 2023.
https://t.co/VsRZmzycXH https://t.co/ysWaHABKoP
Heavy Metals and the Risk of Arthritis
The etiology of arthritis was studied using US NHANES data and suggested that elevated concentrations of trace elements (TE: Pb, Cd, and Cu) were associated with increased risk of arthritis.
https://t.co/z8bzOorqTz https://t.co/u5cQqXDId2
Have a chance to listen to last week's podcast?
Check out our sneak peek and see what Dr. Cush finds surprising.
https://t.co/zQIyVWwA8k https://t.co/I3PEUGUx2L
Survey of 300 Rheums, GI, Derms - concerns w/ new biosimilars
- majority say economics arent favorable to switch to biosimilar
- Yet majority "very to somewhat” comfortable w/ biosimilars
- US: Slow biosimilar uptake due to disappointing costs https://t.co/6dUR4gA3I5 https://t.co/2bLzE70h6y
Im not sure this was necessary but - a metanalysis of 10 RCTs w/ 847 OA patients shows colchicine use in osteoarthritis had no efficacy as far as pain reduction (vs control; SMD= 0.17) & no improvement in function (SMD, - 0.37) https://t.co/67d1ouJyQR https://t.co/6xBJcQCYZt
Metanalysis of 25 studies, betw 1985 - 2021, showed US average annual visits for RA=5.25 for US rheums (vs 3.3 ex-US) & 4.8 US non-rheums. SLE=3.24 & 12.3 for US non-Rheums. FM=1.8 for US rheums & 0.4 vs ex-US Rheums. Rheum Visits Decreased 1982 to 2019 https://t.co/5ugk34MJ3b https://t.co/NDMYZT7pil
Toxic Epiderman Necrolysis vs Acute Cutaneous Lupus Erythematosus
https://t.co/wKX3v01RUb https://t.co/SWwnH7ph04
Specific ACPAs and Autoantibodies Lead to RA-Associated ILD
https://t.co/KLq3CYc20P https://t.co/G7u36CWOTn
EHR study of UK Clinical Practice Research Datalink studied 318 hospitalized gout pts showing there is a 30d increased risk of VTE after gout flare aIRR 2.31 (1.39-3.82), that disappeared 31-90d after. https://t.co/h2v8KbiSwX https://t.co/gsfnR50gTD
Vision Loss with ANCA-Associated Vasculitis
Shelley K. Dhillon, MD, presents her poster at RWCS 2023.
https://t.co/e25SFDXk7O https://t.co/J1AsdE3b0Y
Danish Pop. study of frequency of TMJ and oro-facial Dz in 613 pts w/ #JIA followed 4 yrs. Cumulative incidence of TMJ dz was 30%; 21% had arthritis-induced dentofacial deformity & dentofacial dysfunction (52%). TMJ predicted by younger onset, F, ANA+ https://t.co/M39q3snO3n https://t.co/ajPz27lmvt



