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Abst0242 #ACR21 @RheumNow FROST: 1st line Rx of SJIA 73 pts. two study arms: biologics & GC/MTX arm. In biologic arm 14% IL-1i switched to IL-6i, 0% from IL-6i to IL-1i. 50%GC/MTX eventually initiated biologic therapy . 57% of pts d/cGC use, and 75% had cJADAS-10 score ≤ 2.5 https://t.co/vH0AnocTr2
Olga Petryna DrPetryna ( View Tweet)
Data science for the dumbs. Very informative talk from Dr Jamie Collins! Surely helpful for me. A good way to decide on the best supervised methods for data analysis in machine learning is to separate according to our goal: to explain or to predict? #ACR2021 @RheumNow https://t.co/J0j6VMkoTV
Aurelie Najm AurelieRheumo ( View Tweet)
#ACR21 2nd abstract #0381 from #DESIR cohort by @ElenaNikiUK: •High disease activity & decreased function assoc w/ greater #WorkDisability •Not enough to just treat the disease! Need holistic approaches to improve function, QoL & work outcomes. @RheumNow https://t.co/jIs3Oj7nbJ

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Mrinalini Dey DrMiniDey ( View Tweet)

Completely new one for me, Dr Taniguchi presenting on using ear ultrasound to diagnose and monitor disease activity in relapsing polychondritis. Appears useful, I suspect in clinical practice more so for diagnosis. Abstr#0169 #ACR21 @RheumNow https://t.co/PLJtkYkP3A
Richard Conway RichardPAConway ( View Tweet)
@jhrheumatology Dr. Petri at #ACR21 Great Debate. Safety issues with Voclosporin: 1) Nephrotoxicity 2) Infection 3) CV Risk Factors 4) Malignancy 5) Neurologic toxicity 6) Osteoporosis 7) Drug interactions 8) Deaths 9) Pregnancy contraindication @RheumNow https://t.co/wjluivmKNt
Eric Dein ericdeinmd ( View Tweet)
#ClinicalPearl. Pts have no preference btwn phone or video telemedicine. You can get calls more easily in PJs, technology of internet may be difficult for elderly, hearing impaired & rural with poor internet bandwidth so I would’ve guessed phone was preferred @RheumNow #abst0112 https://t.co/1F4HH9nXB8

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Janet Pope Janetbirdope ( View Tweet)

RheumNow’s expanded coverage of #ACR21 is sponsored in part by @Novartis. All content chosen by RheumNow & its Faculty.

Dr. John Cush RheumNow ( View Tweet)

Is holding MTX during breastfeeding overblown? @MotherToBaby data showed that infants get 0.4% of mom’s dose 24 hrs post-MTX dose. Skip breastfeeding 1 day post-MTX may be safe. Consider monitoring infant CBC. Studies needed to follow infants longitudinally #ACR21 @rheumnow https://t.co/ikJvkk5BjI
TheDaoIndex KDAO2011 ( View Tweet)
#ACR21 Abst#0170: ↑ epicardial adipose tissue volume predicts new coronary plaque development in the following RA patients: ⋆ <10 yrs dz (OR 5.75) ⋆ 1 cardiac risk (OR 3.4) ⋆ statin < 1 yr (OR 3.3) ⋆ w/o calcification at b/l (OR 2.65) @Rheumnow https://t.co/tnyWRVSger https://t.co/uhak4kdbll

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Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Interesting study on 5yr CV event risk in early #rheumatoidarthritis pts who received T2T mgt shows no difference in CVE risk in ERA grp vs control ERA cohort: > Longer remission = protective for CVE > ⬆ HAQ = predictive of CVE Tighter control, ⬇ CVEs @RheumNow #ACR21 abs0282 https://t.co/GG7HPvWd0r
sheila RHEUMarampa ( View Tweet)
Excited for the first full day of #ACR21, reporting for @RheumNow! Esp looking forward to: ⭐Posters: #Epidemiology, #PublicHealth, #COVID19, #SpA, #RheumatoidArthritis, #PatientOutcomes ⭐Plenary session ⭐Scientific sessions covering #axSpA, #PsA and more

Mrinalini Dey DrMiniDey ( View Tweet)

How much ritux for AAV maintenance? Ever since we started using it, no-one's been sure. If absolute B cell depletion is your goal, @VUMCRheum data suggest >3.3mg/d is safest for that 500mg q6m = 2.7 mg/d 500mg q4m = 4.1 mg/d 1000mg q6m = 5.5mg/d #ACR21 ABST0416 @RheumNow https://t.co/mYAgKhHT7j
David Liew drdavidliew ( View Tweet)
Dr. Chambers review @MotherToBaby prospective data on HCQ use in pregnancy (n=279): 👉no major defects (regardless of dose) 👉no oral clefts 👉SGA slightly lower in exposed group b/c of underlying dz 👉no case of retinopathy in babies after 1 year f/u @rheumnow #Pregnancy https://t.co/vw2eryFgro
TheDaoIndex KDAO2011 ( View Tweet)
Abst#271 #ACR21. RA activity predicts left ventricular mass change in pts without CVD ⭐️35% had abnormal LV geometry at baseline TTE ⭐️55% at f/u TTE 3-6 years later ⭐️Increase in concentric remodeling on LV @Rheumnow https://t.co/uHnqITcTy9 https://t.co/KmV8volVwd

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Eric Dein ericdeinmd ( View Tweet)
@DrDDRheum presents on uveitis in SpA. AxSpA>PsA, 30% vs 7.6%. PsA: B27+⬆️ risk, smoking ⁉️ and DMARDs protective. AxSpA: Elevated CRP⬆️ risk, biologics protective. Abstr#0064 #ACR21 @RheumNow https://t.co/psw20RGDst
Richard Conway RichardPAConway ( View Tweet)
Dr. Chambers reviewed @MotherToBaby data of pregnant rheum women during the pandemic noted: ⬆️EtOH use in pregnancy, ⬆️stress, anxiety, depression ⬆️obesity ⬇️likelihood to get prenatal care #ACR21 @rheumnow #RheumPregnancy https://t.co/GCYCIuiunS
TheDaoIndex KDAO2011 ( View Tweet)
#ACR21 Abst#0276: Pulse pressure (PP) = Systolic BP - Diastolic BP, measures arterial compliance ⭐️RA: higher PP than controls ⭐️PP was independent risk factor for subclinical atherosclerosis ▶️ Look at the vitals, we have this at every pt visit! @Rheumnow https://t.co/KZaf1AwO6Q https://t.co/kN4xGxWiV9

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Eric Dein ericdeinmd ( View Tweet)
It's what's below the surface that's most scary. see: RA & the heart - why do RA pts without cardiovasc dx/Sx get LV remodelling over time - why is it worse with worse RA control? RA goes deeper than the joints & our pts need to hear that! @Columbia #ACR21 ABST0272 @RheumNow https://t.co/NDHLZwoEjy
David Liew drdavidliew ( View Tweet)
Dr Springer on pharmacological response of RTX in ANCA-vasculitis. Suggest that 500mg every 6 months may not achieve sufficient B cell depletion in all. What are the clinical implications? Is anyone dosing 500mg as standard? Abstr#0416 #ACR21 @RheumNow https://t.co/w36hSYbW1B
Richard Conway RichardPAConway ( View Tweet)
Some great #SpA posters on #WorkParticipation #ACR21 Abs#0358 •~700 pts •379 (64.2%) took sick leave in last 12m •#Absenteeism in 23.7% & #presenteeism in 84.1% •Huge impact on work participation in SpA despite incr no. of therapeutic agents @RheumNow https://t.co/pwz4s8D1FU https://t.co/wpbjeXNpgm

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Mrinalini Dey DrMiniDey ( View Tweet)
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